PhosphoNET

           
Protein Info 
   
Short Name:  IL4R
Full Name:  Interleukin-4 receptor subunit alpha
Alias:  582J2.1; CD124; CD124 antigen; IL4RA; IL-4R-alpha; Interleukin 4 receptor; Interleukin-4 receptor alpha chain precursor; Soluble interleukin-4 receptor alpha chain
Type:  Receptor, cytokine
Mass (Da):  89658
Number AA:  825
UniProt ID:  P24394
International Prot ID:  IPI00444383
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005576  GO:0005887   Uniprot OncoNet
Molecular Function:  GO:0004913  GO:0005057   PhosphoSite+ KinaseNET
Biological Process:  GO:0006955  GO:0007165   Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S285IIQDAQGSQWEKRSR
Site 2S336KEMPFQGSGKSAWCP
Site 3S383EVEEEKGSFCASPES
Site 4S387EKGSFCASPESSRDD
Site 5S390SFCASPESSRDDFQE
Site 6S391FCASPESSRDDFQEG
Site 7S436ESCLLPPSGSTSAHM
Site 8S438CLLPPSGSTSAHMPW
Site 9S440LPPSGSTSAHMPWDE
Site 10S470QPLHLEPSPPASPTQ
Site 11S474LEPSPPASPTQSPDN
Site 12T476PSPPASPTQSPDNLT
Site 13S478PPASPTQSPDNLTCT
Site 14T483TQSPDNLTCTETPLV
Site 15Y497VIAGNPAYRSFSNSL
Site 16S499AGNPAYRSFSNSLSQ
Site 17S501NPAYRSFSNSLSQSP
Site 18S503AYRSFSNSLSQSPCP
Site 19S505RSFSNSLSQSPCPRE
Site 20S507FSNSLSQSPCPRELG
Site 21S537MPCVPQLSEPTTVPQ
Site 22T541PQLSEPTTVPQPEPE
Site 23T549VPQPEPETWEQILRR
Site 24S569GAAAAPVSAPTSGYQ
Site 25S573APVSAPTSGYQEFVH
Site 26Y575VSAPTSGYQEFVHAV
Site 27S590EQGGTQASAVVGLGP
Site 28Y603GPPGEAGYKAFSSLL
Site 29S625EKCGFGASSGEEGYK
Site 30Y631ASSGEEGYKPFQDLI
Site 31S664LDREPPRSPQSSHLP
Site 32S667EPPRSPQSSHLPSSS
Site 33S668PPRSPQSSHLPSSSP
Site 34S672PQSSHLPSSSPEHLG
Site 35S673QSSHLPSSSPEHLGL
Site 36S674SSHLPSSSPEHLGLE
Site 37Y713SLGSGIVYSALTCHL
Site 38T736GQEDGGQTPVMASPC
Site 39S752GCCCGDRSSPPTTPL
Site 40S753CCCGDRSSPPTTPLR
Site 41T756GDRSSPPTTPLRAPD
Site 42T757DRSSPPTTPLRAPDP
Site 43S765PLRAPDPSPGGVPLE
Site 44S783CPASLAPSGISEKSK
Site 45S786SLAPSGISEKSKSSS
Site 46S789PSGISEKSKSSSSFH
Site 47S791GISEKSKSSSSFHPA
Site 48S792ISEKSKSSSSFHPAP
Site 49S793SEKSKSSSSFHPAPG
Site 50S794EKSKSSSSFHPAPGN
Site 51S804PAPGNAQSSSQTPKI
Site 52S806PGNAQSSSQTPKIVN
Site 53T808NAQSSSQTPKIVNFV
Site 54Y821FVSVGPTYMRVS___
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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