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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AP1M2
Full Name:
AP-1 complex subunit mu-2
Alias:
Adaptor-related protein complex 1 mu-2; Clathrin assembly protein assembly protein complex 1 medium chain 2; Golgi adaptor HA1/AP1 adaptin mu-2; HSMU1B; MU1B; MU-1B; Mu1B-adaptin; Mu-adaptin 2
Type:
Membrane, Clathrin adaptor complex, Cytoplasmic vesicle, Golgi apparatus protein
Mass (Da):
48108
Number AA:
423
UniProt ID:
Q9Y6Q5
International Prot ID:
IPI00002552
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0030131
GO:0031410
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0016044
GO:0006892
GO:0006605
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S2
_
_
_
_
_
_
M
S
A
S
A
V
F
I
L
Site 2
S4
_
_
_
_
M
S
A
S
A
V
F
I
L
D
V
Site 3
S18
V
K
G
K
P
L
I
S
R
N
Y
K
G
D
V
Site 4
Y21
K
P
L
I
S
R
N
Y
K
G
D
V
A
M
S
Site 5
Y66
W
I
K
H
S
N
L
Y
L
V
A
T
T
S
K
Site 6
S78
T
S
K
N
A
N
A
S
L
V
Y
S
F
L
Y
Site 7
Y94
T
I
E
V
F
C
E
Y
F
K
E
L
E
E
E
Site 8
S102
F
K
E
L
E
E
E
S
I
R
D
N
F
V
I
Site 9
Y134
D
S
K
I
L
Q
E
Y
I
T
Q
Q
S
N
K
Site 10
S147
N
K
L
E
T
G
K
S
R
V
P
P
T
V
T
Site 11
T152
G
K
S
R
V
P
P
T
V
T
N
A
V
S
W
Site 12
T154
S
R
V
P
P
T
V
T
N
A
V
S
W
R
S
Site 13
S158
P
T
V
T
N
A
V
S
W
R
S
E
G
I
K
Site 14
Y166
W
R
S
E
G
I
K
Y
K
K
N
E
V
F
I
Site 15
T223
D
R
V
L
F
E
L
T
G
R
S
K
N
K
S
Site 16
S226
L
F
E
L
T
G
R
S
K
N
K
S
V
E
L
Site 17
S230
T
G
R
S
K
N
K
S
V
E
L
E
D
V
K
Site 18
T252
S
R
F
D
N
D
R
T
I
S
F
I
P
P
D
Site 19
S254
F
D
N
D
R
T
I
S
F
I
P
P
D
G
D
Site 20
S266
D
G
D
F
E
L
M
S
Y
R
L
S
T
Q
V
Site 21
Y267
G
D
F
E
L
M
S
Y
R
L
S
T
Q
V
K
Site 22
S270
E
L
M
S
Y
R
L
S
T
Q
V
K
P
L
I
Site 23
S287
E
S
V
I
E
K
F
S
H
S
R
V
E
I
M
Site 24
S305
K
G
Q
F
K
K
Q
S
V
A
N
G
V
E
I
Site 25
S318
E
I
S
V
P
V
P
S
D
A
D
S
P
R
F
Site 26
S322
P
V
P
S
D
A
D
S
P
R
F
K
T
S
V
Site 27
T327
A
D
S
P
R
F
K
T
S
V
G
S
A
K
Y
Site 28
S328
D
S
P
R
F
K
T
S
V
G
S
A
K
Y
V
Site 29
S331
R
F
K
T
S
V
G
S
A
K
Y
V
P
E
R
Site 30
Y334
T
S
V
G
S
A
K
Y
V
P
E
R
N
V
V
Site 31
S344
E
R
N
V
V
I
W
S
I
K
S
F
P
G
G
Site 32
Y354
S
F
P
G
G
K
E
Y
L
M
R
A
H
F
G
Site 33
S364
R
A
H
F
G
L
P
S
V
E
K
E
E
V
E
Site 34
Y403
K
I
I
E
K
S
G
Y
Q
A
L
P
W
V
R
Site 35
Y411
Q
A
L
P
W
V
R
Y
I
T
Q
S
G
D
Y
Site 36
T413
L
P
W
V
R
Y
I
T
Q
S
G
D
Y
Q
L
Site 37
Y418
Y
I
T
Q
S
G
D
Y
Q
L
R
T
S
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation