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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AP4B1
Full Name:
AP-4 complex subunit beta-1
Alias:
Adapter-related protein complex 4 beta 1; Adaptor-related protein complex 4, beta 1; Adaptor-related protein complex 4, beta 1 subunit; AP-4 adapter complex beta; AP-4 complex beta-1; Beta 4 subunit of AP-4; Beta subunit of AP-4; BETA-4
Type:
Adaptor/scaffold
Mass (Da):
83260
Number AA:
739
UniProt ID:
Q9Y6B7
International Prot ID:
IPI00002150
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030131
GO:0005625
GO:0005802
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008565
PhosphoSite+
KinaseNET
Biological Process:
GO:0006886
GO:0016192
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y29
I
Q
A
D
R
L
R
Y
R
N
V
I
Q
R
V
Site 2
Y39
V
I
Q
R
V
I
R
Y
M
T
Q
G
L
D
M
Site 3
T41
Q
R
V
I
R
Y
M
T
Q
G
L
D
M
S
G
Site 4
Y71
Q
K
K
L
V
Y
L
Y
M
C
T
Y
A
P
L
Site 5
T74
L
V
Y
L
Y
M
C
T
Y
A
P
L
K
P
D
Site 6
T89
L
A
L
L
A
I
N
T
L
C
K
D
C
S
D
Site 7
S134
N
G
L
R
D
K
A
S
Y
V
R
R
V
A
V
Site 8
Y135
G
L
R
D
K
A
S
Y
V
R
R
V
A
V
L
Site 9
Y165
G
A
L
V
N
E
L
Y
S
L
L
R
D
Q
D
Site 10
Y225
V
L
N
F
L
L
R
Y
Q
P
R
S
E
E
E
Site 11
S229
L
L
R
Y
Q
P
R
S
E
E
E
L
F
D
I
Site 12
S242
D
I
L
N
L
L
D
S
F
L
K
S
S
S
P
Site 13
S306
H
V
R
Q
I
L
H
S
L
P
G
H
F
S
S
Site 14
Y315
P
G
H
F
S
S
H
Y
K
K
F
F
C
S
Y
Site 15
Y322
Y
K
K
F
F
C
S
Y
S
E
P
H
Y
I
K
Site 16
Y327
C
S
Y
S
E
P
H
Y
I
K
L
Q
K
V
E
Site 17
Y355
V
L
E
E
L
R
G
Y
C
T
D
V
S
A
D
Site 18
S360
R
G
Y
C
T
D
V
S
A
D
F
A
Q
A
A
Site 19
T399
L
R
Q
E
H
I
T
T
V
V
V
Q
T
F
R
Site 20
Y455
E
R
I
P
N
A
P
Y
V
L
E
D
F
V
E
Site 21
S466
D
F
V
E
N
V
K
S
E
T
F
P
A
V
K
Site 22
Y500
D
M
L
G
R
L
L
Y
Y
C
I
E
E
E
K
Site 23
Y501
M
L
G
R
L
L
Y
Y
C
I
E
E
E
K
D
Site 24
S535
E
V
K
R
I
L
C
S
P
K
S
D
P
T
L
Site 25
T562
S
W
A
S
D
F
N
T
L
V
P
V
Y
G
K
Site 26
T591
C
D
P
E
L
P
K
T
S
S
F
A
A
S
G
Site 27
S593
P
E
L
P
K
T
S
S
F
A
A
S
G
P
L
Site 28
S597
K
T
S
S
F
A
A
S
G
P
L
I
P
E
E
Site 29
T627
L
V
P
N
R
Q
L
T
A
D
Y
F
E
K
T
Site 30
Y630
N
R
Q
L
T
A
D
Y
F
E
K
T
W
L
S
Site 31
T656
R
G
E
F
H
P
D
T
L
Q
M
A
L
Q
V
Site 32
S672
N
I
Q
T
I
A
M
S
R
A
G
S
R
P
W
Site 33
S676
I
A
M
S
R
A
G
S
R
P
W
K
A
Y
L
Site 34
Y682
G
S
R
P
W
K
A
Y
L
S
A
Q
D
D
T
Site 35
S684
R
P
W
K
A
Y
L
S
A
Q
D
D
T
G
C
Site 36
T689
Y
L
S
A
Q
D
D
T
G
C
L
F
L
T
E
Site 37
S704
L
L
L
E
P
G
N
S
E
M
Q
I
S
V
K
Site 38
S709
G
N
S
E
M
Q
I
S
V
K
Q
N
E
A
R
Site 39
T719
Q
N
E
A
R
T
E
T
L
N
S
F
I
S
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation