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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
HEBP2
Full Name:
Heme-binding protein 2
Alias:
Placental 23; PP23; SOUL
Type:
Mass (Da):
22875
Number AA:
205
UniProt ID:
Q9Y5Z4
International Prot ID:
IPI00644697
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005739
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T22
A
A
A
Q
A
V
E
T
P
G
W
K
A
P
E
Site 2
S37
D
A
G
P
Q
P
G
S
Y
E
I
R
H
Y
G
Site 3
Y38
A
G
P
Q
P
G
S
Y
E
I
R
H
Y
G
P
Site 4
Y43
G
S
Y
E
I
R
H
Y
G
P
A
K
W
V
S
Site 5
S50
Y
G
P
A
K
W
V
S
T
S
V
E
S
M
D
Site 6
T51
G
P
A
K
W
V
S
T
S
V
E
S
M
D
W
Site 7
S52
P
A
K
W
V
S
T
S
V
E
S
M
D
W
D
Site 8
T64
D
W
D
S
A
I
Q
T
G
F
T
K
L
N
S
Site 9
S71
T
G
F
T
K
L
N
S
Y
I
Q
G
K
N
E
Site 10
T86
K
E
M
K
I
K
M
T
A
P
V
T
S
Y
V
Site 11
T90
I
K
M
T
A
P
V
T
S
Y
V
E
P
G
S
Site 12
S91
K
M
T
A
P
V
T
S
Y
V
E
P
G
S
G
Site 13
Y92
M
T
A
P
V
T
S
Y
V
E
P
G
S
G
P
Site 14
S97
T
S
Y
V
E
P
G
S
G
P
F
S
E
S
T
Site 15
S101
E
P
G
S
G
P
F
S
E
S
T
I
T
I
S
Site 16
S108
S
E
S
T
I
T
I
S
L
Y
I
P
S
E
Q
Site 17
Y110
S
T
I
T
I
S
L
Y
I
P
S
E
Q
Q
F
Site 18
S125
D
P
P
R
P
L
E
S
D
V
F
I
E
D
R
Site 19
T136
I
E
D
R
A
E
M
T
V
F
V
R
S
F
D
Site 20
S141
E
M
T
V
F
V
R
S
F
D
G
F
S
S
A
Site 21
S146
V
R
S
F
D
G
F
S
S
A
Q
K
N
Q
E
Site 22
S147
R
S
F
D
G
F
S
S
A
Q
K
N
Q
E
Q
Site 23
T157
K
N
Q
E
Q
L
L
T
L
A
S
I
L
R
E
Site 24
S160
E
Q
L
L
T
L
A
S
I
L
R
E
D
G
K
Site 25
Y174
K
V
F
D
E
K
V
Y
Y
T
A
G
Y
N
S
Site 26
Y175
V
F
D
E
K
V
Y
Y
T
A
G
Y
N
S
P
Site 27
Y179
K
V
Y
Y
T
A
G
Y
N
S
P
V
K
L
L
Site 28
S181
Y
Y
T
A
G
Y
N
S
P
V
K
L
L
N
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation