KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
SNX8
Full Name:
Sorting nexin-8
Alias:
Type:
Mass (Da):
52569
Number AA:
465
UniProt ID:
Q9Y5X2
International Prot ID:
IPI00001885
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
GO:0035091
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0007154
GO:0015031
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S31
E
E
A
D
P
P
A
S
D
L
P
T
P
Q
A
Site 2
T35
P
P
A
S
D
L
P
T
P
Q
A
I
E
P
Q
Site 3
S52
V
Q
Q
V
P
A
P
S
R
M
Q
M
P
Q
G
Site 4
Y95
L
F
L
K
H
V
E
Y
E
V
S
S
Q
R
F
Site 5
S98
K
H
V
E
Y
E
V
S
S
Q
R
F
K
S
S
Site 6
S99
H
V
E
Y
E
V
S
S
Q
R
F
K
S
S
V
Site 7
S104
V
S
S
Q
R
F
K
S
S
V
Y
R
R
Y
N
Site 8
S105
S
S
Q
R
F
K
S
S
V
Y
R
R
Y
N
D
Site 9
Y107
Q
R
F
K
S
S
V
Y
R
R
Y
N
D
F
V
Site 10
Y110
K
S
S
V
Y
R
R
Y
N
D
F
V
V
F
Q
Site 11
S178
L
K
L
F
L
S
F
S
G
S
D
V
Q
N
K
Site 12
S180
L
F
L
S
F
S
G
S
D
V
Q
N
K
L
K
Site 13
Y229
R
E
L
I
R
N
I
Y
N
S
F
H
K
L
R
Site 14
S231
L
I
R
N
I
Y
N
S
F
H
K
L
R
D
R
Site 15
S244
D
R
A
E
R
I
A
S
R
A
I
D
N
A
A
Site 16
S265
K
E
L
S
A
I
G
S
D
T
T
P
L
P
S
Site 17
T268
S
A
I
G
S
D
T
T
P
L
P
S
W
A
A
Site 18
S272
S
D
T
T
P
L
P
S
W
A
A
L
N
S
S
Site 19
S278
P
S
W
A
A
L
N
S
S
T
W
G
S
L
K
Site 20
S279
S
W
A
A
L
N
S
S
T
W
G
S
L
K
Q
Site 21
S283
L
N
S
S
T
W
G
S
L
K
Q
A
L
K
G
Site 22
S326
L
F
L
D
L
L
Q
S
Y
K
D
L
C
E
R
Site 23
Y349
H
Q
R
A
L
H
K
Y
S
L
M
K
R
Q
M
Site 24
S368
A
Q
N
R
E
P
E
S
V
E
Q
L
E
S
R
Site 25
S374
E
S
V
E
Q
L
E
S
R
I
V
E
Q
E
N
Site 26
Y391
Q
T
M
E
L
R
N
Y
F
S
L
Y
C
L
H
Site 27
Y395
L
R
N
Y
F
S
L
Y
C
L
H
Q
E
T
Q
Site 28
S421
I
L
R
A
F
V
N
S
Q
I
Q
G
H
K
E
Site 29
S441
N
D
L
R
P
K
L
S
C
L
F
A
G
P
H
Site 30
T450
L
F
A
G
P
H
S
T
L
T
P
P
C
S
P
Site 31
T452
A
G
P
H
S
T
L
T
P
P
C
S
P
P
E
Site 32
S456
S
T
L
T
P
P
C
S
P
P
E
D
G
L
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation