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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NRAGE
Full Name:
Melanoma-associated antigen D1
Alias:
Dlxin-1; MAGD1; MAGED1; MAGE-D1 antigen; Melanoma antigen family D, 1; Melanoma-associated antigen D1; MGD1; Neurotrophin receptor-interacting MAGE; PP2250; PRO2292
Type:
Adapter/scaffold protein
Mass (Da):
86161
Number AA:
778
UniProt ID:
Q9Y5V3
International Prot ID:
IPI00328354
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0019898
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0008624
GO:0050680
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T42
Q
I
S
E
A
P
P
T
N
Q
A
T
A
A
A
Site 2
T46
A
P
P
T
N
Q
A
T
A
A
A
S
P
Q
S
Site 3
S50
N
Q
A
T
A
A
A
S
P
Q
S
S
Q
P
P
Site 4
S53
T
A
A
A
S
P
Q
S
S
Q
P
P
T
A
N
Site 5
S54
A
A
A
S
P
Q
S
S
Q
P
P
T
A
N
E
Site 6
T58
P
Q
S
S
Q
P
P
T
A
N
E
M
A
D
I
Site 7
S76
A
A
A
A
R
P
K
S
A
F
K
V
Q
N
A
Site 8
T85
F
K
V
Q
N
A
T
T
K
G
P
N
G
V
Y
Site 9
Y92
T
K
G
P
N
G
V
Y
D
F
S
Q
A
H
N
Site 10
S95
P
N
G
V
Y
D
F
S
Q
A
H
N
A
K
D
Site 11
S114
Q
P
K
A
A
F
K
S
Q
N
A
T
P
K
G
Site 12
T118
A
F
K
S
Q
N
A
T
P
K
G
P
N
A
A
Site 13
Y126
P
K
G
P
N
A
A
Y
D
F
S
Q
A
A
T
Site 14
S129
P
N
A
A
Y
D
F
S
Q
A
A
T
T
G
E
Site 15
S142
G
E
L
A
A
N
K
S
E
M
A
F
K
A
Q
Site 16
T160
T
K
V
G
P
N
A
T
Y
N
F
S
Q
S
L
Site 17
Y161
K
V
G
P
N
A
T
Y
N
F
S
Q
S
L
N
Site 18
S164
P
N
A
T
Y
N
F
S
Q
S
L
N
A
N
D
Site 19
S166
A
T
Y
N
F
S
Q
S
L
N
A
N
D
L
A
Site 20
T179
L
A
N
S
R
P
K
T
P
F
K
A
W
N
D
Site 21
T188
F
K
A
W
N
D
T
T
K
A
P
T
A
D
T
Site 22
T197
A
P
T
A
D
T
Q
T
Q
N
V
N
Q
A
K
Site 23
S208
N
Q
A
K
M
A
T
S
Q
A
D
I
E
T
D
Site 24
T214
T
S
Q
A
D
I
E
T
D
P
G
I
S
E
P
Site 25
S229
D
G
A
T
A
Q
T
S
A
D
G
S
Q
A
Q
Site 26
S233
A
Q
T
S
A
D
G
S
Q
A
Q
N
L
E
S
Site 27
T274
R
A
P
L
A
A
G
T
W
R
S
A
P
V
P
Site 28
T283
R
S
A
P
V
P
V
T
T
Q
N
P
P
G
A
Site 29
T284
S
A
P
V
P
V
T
T
Q
N
P
P
G
A
P
Site 30
T298
P
P
N
V
L
W
Q
T
P
L
A
W
Q
N
P
Site 31
T312
P
S
G
W
Q
N
Q
T
A
R
Q
T
P
P
A
Site 32
T316
Q
N
Q
T
A
R
Q
T
P
P
A
R
Q
S
P
Site 33
S322
Q
T
P
P
A
R
Q
S
P
P
A
R
Q
T
P
Site 34
T328
Q
S
P
P
A
R
Q
T
P
P
A
W
Q
N
P
Site 35
T382
Q
N
P
P
G
W
Q
T
P
P
G
W
Q
T
P
Site 36
T388
Q
T
P
P
G
W
Q
T
P
P
G
W
Q
G
P
Site 37
T420
P
P
D
W
P
L
P
T
D
W
P
L
P
P
D
Site 38
S445
D
W
Q
N
L
R
P
S
P
N
L
R
P
S
P
Site 39
S451
P
S
P
N
L
R
P
S
P
N
S
R
A
S
Q
Site 40
S454
N
L
R
P
S
P
N
S
R
A
S
Q
N
P
G
Site 41
S457
P
S
P
N
S
R
A
S
Q
N
P
G
A
A
Q
Site 42
Y481
R
A
N
K
L
V
K
Y
L
M
L
K
D
Y
T
Site 43
Y487
K
Y
L
M
L
K
D
Y
T
K
V
P
I
K
R
Site 44
T488
Y
L
M
L
K
D
Y
T
K
V
P
I
K
R
S
Site 45
Y505
L
R
D
I
I
R
E
Y
T
D
V
Y
P
E
I
Site 46
T506
R
D
I
I
R
E
Y
T
D
V
Y
P
E
I
I
Site 47
Y509
I
R
E
Y
T
D
V
Y
P
E
I
I
E
R
A
Site 48
Y538
I
D
K
E
E
H
L
Y
I
L
I
S
T
P
E
Site 49
T543
H
L
Y
I
L
I
S
T
P
E
S
L
A
G
I
Site 50
S578
F
M
N
G
N
R
A
S
E
A
V
L
W
E
A
Site 51
T608
G
D
L
R
K
L
L
T
Y
E
F
V
K
Q
K
Site 52
Y609
D
L
R
K
L
L
T
Y
E
F
V
K
Q
K
Y
Site 53
Y616
Y
E
F
V
K
Q
K
Y
L
D
Y
R
R
V
P
Site 54
Y619
V
K
Q
K
Y
L
D
Y
R
R
V
P
N
S
N
Site 55
S625
D
Y
R
R
V
P
N
S
N
P
P
E
Y
E
F
Site 56
Y630
P
N
S
N
P
P
E
Y
E
F
L
W
G
L
R
Site 57
S638
E
F
L
W
G
L
R
S
Y
H
E
T
S
K
M
Site 58
Y639
F
L
W
G
L
R
S
Y
H
E
T
S
K
M
K
Site 59
T642
G
L
R
S
Y
H
E
T
S
K
M
K
V
L
R
Site 60
S643
L
R
S
Y
H
E
T
S
K
M
K
V
L
R
F
Site 61
T663
K
R
D
P
R
D
W
T
A
Q
F
M
E
A
A
Site 62
S702
G
I
G
D
E
A
V
S
G
P
W
S
W
D
D
Site 63
S706
E
A
V
S
G
P
W
S
W
D
D
I
E
F
E
Site 64
Y738
P
F
T
F
W
A
R
Y
H
Q
N
A
R
S
R
Site 65
T749
A
R
S
R
F
P
Q
T
F
A
G
P
I
I
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation