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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NOX1
Full Name:
NADPH oxidase 1
Alias:
Mitogenic oxidase 1;NADH/NADPH mitogenic oxidase subunit P65-MOX;NOH-1
Type:
Mass (Da):
64871
Number AA:
564
UniProt ID:
Q9Y5S8
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y33
F
V
D
A
F
L
K
Y
E
K
A
D
K
Y
Y
Site 2
Y39
K
Y
E
K
A
D
K
Y
Y
Y
T
R
K
I
L
Site 3
Y40
Y
E
K
A
D
K
Y
Y
Y
T
R
K
I
L
G
Site 4
Y41
E
K
A
D
K
Y
Y
Y
T
R
K
I
L
G
S
Site 5
T49
T
R
K
I
L
G
S
T
L
A
C
A
R
A
S
Site 6
S84
S
F
L
R
G
T
C
S
F
C
S
R
T
L
R
Site 7
T89
T
C
S
F
C
S
R
T
L
R
K
Q
L
D
H
Site 8
T99
K
Q
L
D
H
N
L
T
F
H
K
L
V
A
Y
Site 9
Y126
H
L
F
N
F
D
C
Y
S
R
S
R
Q
A
T
Site 10
S127
L
F
N
F
D
C
Y
S
R
S
R
Q
A
T
D
Site 11
S129
N
F
D
C
Y
S
R
S
R
Q
A
T
D
G
S
Site 12
T133
Y
S
R
S
R
Q
A
T
D
G
S
L
A
S
I
Site 13
S136
S
R
Q
A
T
D
G
S
L
A
S
I
L
S
S
Site 14
S142
G
S
L
A
S
I
L
S
S
L
S
H
D
E
K
Site 15
S143
S
L
A
S
I
L
S
S
L
S
H
D
E
K
K
Site 16
S145
A
S
I
L
S
S
L
S
H
D
E
K
K
G
G
Site 17
T163
N
P
I
Q
S
R
N
T
T
V
E
Y
V
T
F
Site 18
T164
P
I
Q
S
R
N
T
T
V
E
Y
V
T
F
T
Site 19
Y167
S
R
N
T
T
V
E
Y
V
T
F
T
S
I
A
Site 20
Y200
T
E
F
I
R
R
S
Y
F
E
V
F
W
Y
T
Site 21
T231
G
G
I
V
R
G
Q
T
E
E
S
M
N
E
S
Site 22
S238
T
E
E
S
M
N
E
S
H
P
R
K
C
A
E
Site 23
Y280
I
L
A
P
V
I
L
Y
I
C
E
R
I
L
R
Site 24
Y289
C
E
R
I
L
R
F
Y
R
S
Q
Q
K
V
V
Site 25
S291
R
I
L
R
F
Y
R
S
Q
Q
K
V
V
I
T
Site 26
T341
L
L
E
W
H
P
F
T
L
T
S
A
P
E
E
Site 27
T343
E
W
H
P
F
T
L
T
S
A
P
E
E
D
F
Site 28
S352
A
P
E
E
D
F
F
S
I
H
I
R
A
A
G
Site 29
T362
I
R
A
A
G
D
W
T
E
N
L
I
R
A
F
Site 30
Y373
I
R
A
F
E
Q
Q
Y
S
P
I
P
R
I
E
Site 31
S374
R
A
F
E
Q
Q
Y
S
P
I
P
R
I
E
V
Site 32
S389
D
G
P
F
G
T
A
S
E
D
V
F
Q
Y
E
Site 33
Y434
N
L
K
T
K
K
I
Y
F
Y
W
I
C
R
E
Site 34
Y436
K
T
K
K
I
Y
F
Y
W
I
C
R
E
T
G
Site 35
S454
W
F
N
N
L
L
T
S
L
E
Q
E
M
E
E
Site 36
T503
V
T
G
L
K
Q
K
T
S
F
G
R
P
M
W
Site 37
S504
T
G
L
K
Q
K
T
S
F
G
R
P
M
W
D
Site 38
T519
N
E
F
S
T
I
A
T
S
H
P
K
S
V
V
Site 39
S520
E
F
S
T
I
A
T
S
H
P
K
S
V
V
G
Site 40
S539
G
P
R
T
L
A
K
S
L
R
K
C
C
H
R
Site 41
Y547
L
R
K
C
C
H
R
Y
S
S
L
D
P
R
K
Site 42
S548
R
K
C
C
H
R
Y
S
S
L
D
P
R
K
V
Site 43
S549
K
C
C
H
R
Y
S
S
L
D
P
R
K
V
Q
Site 44
Y558
D
P
R
K
V
Q
F
Y
F
N
K
E
N
F
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation