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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TRPV2
Full Name:
Transient receptor potential cation channel subfamily V member 2
Alias:
Osm-9-like TRP channel 2; OTRPC2; Transient receptor potential cation channel, subfamily V, member 2; Vanilloid receptor-like protein 1; VRL; VRL1; VRL-1
Type:
Intracellular, Cytoplasm, Plasma membrane, Integral plasma membrane, Melanosome protein
Mass (Da):
85981
Number AA:
764
UniProt ID:
Q9Y5S1
International Prot ID:
IPI00784451
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005887
GO:0042470
Uniprot
OncoNet
Molecular Function:
GO:0005262
GO:0005509
PhosphoSite+
KinaseNET
Biological Process:
GO:0006816
GO:0007600
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
T
S
P
S
S
S
P
V
F
R
L
Site 2
S6
_
_
M
T
S
P
S
S
S
P
V
F
R
L
E
Site 3
S7
_
M
T
S
P
S
S
S
P
V
F
R
L
E
T
Site 4
T14
S
P
V
F
R
L
E
T
L
D
G
G
Q
E
D
Site 5
S23
D
G
G
Q
E
D
G
S
E
A
D
R
G
K
L
Site 6
S34
R
G
K
L
D
F
G
S
G
L
P
P
M
E
S
Site 7
S41
S
G
L
P
P
M
E
S
Q
F
Q
G
E
D
R
Site 8
Y60
Q
I
R
V
N
L
N
Y
R
K
G
T
G
A
S
Site 9
T64
N
L
N
Y
R
K
G
T
G
A
S
Q
P
D
P
Site 10
S84
D
R
L
F
N
A
V
S
R
G
V
P
E
D
L
Site 11
Y97
D
L
A
G
L
P
E
Y
L
S
K
T
S
K
Y
Site 12
S99
A
G
L
P
E
Y
L
S
K
T
S
K
Y
L
T
Site 13
Y104
Y
L
S
K
T
S
K
Y
L
T
D
S
E
Y
T
Site 14
T106
S
K
T
S
K
Y
L
T
D
S
E
Y
T
E
G
Site 15
S108
T
S
K
Y
L
T
D
S
E
Y
T
E
G
S
T
Site 16
Y110
K
Y
L
T
D
S
E
Y
T
E
G
S
T
G
K
Site 17
S145
L
L
Q
I
D
R
D
S
G
N
P
Q
P
L
V
Site 18
Y160
N
A
Q
C
T
D
D
Y
Y
R
G
H
S
A
L
Site 19
Y161
A
Q
C
T
D
D
Y
Y
R
G
H
S
A
L
H
Site 20
S165
D
D
Y
Y
R
G
H
S
A
L
H
I
A
I
E
Site 21
Y207
K
G
Q
G
T
C
F
Y
F
G
E
L
P
L
S
Site 22
Y227
K
Q
W
D
V
V
S
Y
L
L
E
N
P
H
Q
Site 23
S237
E
N
P
H
Q
P
A
S
L
Q
A
T
D
S
Q
Site 24
T241
Q
P
A
S
L
Q
A
T
D
S
Q
G
N
T
V
Site 25
S243
A
S
L
Q
A
T
D
S
Q
G
N
T
V
L
H
Site 26
T283
A
G
A
R
L
C
P
T
V
Q
L
E
D
I
R
Site 27
T296
I
R
N
L
Q
D
L
T
P
L
K
L
A
A
K
Site 28
S319
H
I
L
Q
R
E
F
S
G
L
S
H
L
S
R
Site 29
S322
Q
R
E
F
S
G
L
S
H
L
S
R
K
F
T
Site 30
S325
F
S
G
L
S
H
L
S
R
K
F
T
E
W
C
Site 31
T329
S
H
L
S
R
K
F
T
E
W
C
Y
G
P
V
Site 32
Y333
R
K
F
T
E
W
C
Y
G
P
V
R
V
S
L
Site 33
S345
V
S
L
Y
D
L
A
S
V
D
S
C
E
E
N
Site 34
S348
Y
D
L
A
S
V
D
S
C
E
E
N
S
V
L
Site 35
Y523
G
F
Q
H
T
G
I
Y
S
V
M
I
Q
K
V
Site 36
S524
F
Q
H
T
G
I
Y
S
V
M
I
Q
K
V
I
Site 37
Y755
D
G
A
S
E
E
N
Y
V
P
V
Q
L
L
Q
Site 38
S763
V
P
V
Q
L
L
Q
S
N
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation