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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PCYT1B
Full Name:
Choline-phosphate cytidylyltransferase B
Alias:
CCT-beta;CTP:phosphocholine cytidylyltransferase B;Phosphorylcholine transferase B
Type:
Mass (Da):
41940
Number AA:
369
UniProt ID:
Q9Y5K3
International Prot ID:
IPI00219338
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005783
Uniprot
OncoNet
Molecular Function:
GO:0004105
PhosphoSite+
KinaseNET
Biological Process:
GO:0006656
GO:0007283
Phosida
TranscriptoNet
STRING
Kinexus Products
CTP: phosphocholine cytidylyltransferase isoform B S315+S319 phosphosite-specific antibody AB-PN546#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-PN546
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
V
V
T
T
D
A
E
S
E
T
G
I
P
K
S
Site 2
S17
S
E
T
G
I
P
K
S
L
S
N
E
P
P
S
Site 3
S19
T
G
I
P
K
S
L
S
N
E
P
P
S
E
T
Site 4
S24
S
L
S
N
E
P
P
S
E
T
M
E
E
I
E
Site 5
T33
T
M
E
E
I
E
H
T
C
P
Q
P
R
L
T
Site 6
T40
T
C
P
Q
P
R
L
T
L
T
A
P
A
P
F
Site 7
T42
P
Q
P
R
L
T
L
T
A
P
A
P
F
A
D
Site 8
T71
I
A
Q
A
R
L
G
T
P
A
D
R
P
V
R
Site 9
Y80
A
D
R
P
V
R
V
Y
A
D
G
I
F
D
L
Site 10
T101
R
A
L
M
Q
A
K
T
L
F
P
N
S
Y
L
Site 11
T118
G
V
C
S
D
D
L
T
H
K
F
K
G
F
T
Site 12
T125
T
H
K
F
K
G
F
T
V
M
N
E
A
E
R
Site 13
Y133
V
M
N
E
A
E
R
Y
E
A
L
R
H
C
R
Site 14
Y141
E
A
L
R
H
C
R
Y
V
D
E
V
I
R
D
Site 15
T152
V
I
R
D
A
P
W
T
L
T
P
E
F
L
E
Site 16
T154
R
D
A
P
W
T
L
T
P
E
F
L
E
K
H
Site 17
Y173
V
A
H
D
D
I
P
Y
S
S
A
G
S
D
D
Site 18
S174
A
H
D
D
I
P
Y
S
S
A
G
S
D
D
V
Site 19
S178
I
P
Y
S
S
A
G
S
D
D
V
Y
K
H
I
Site 20
Y182
S
A
G
S
D
D
V
Y
K
H
I
K
E
A
G
Site 21
T194
E
A
G
M
F
V
P
T
Q
R
T
E
G
I
S
Site 22
T197
M
F
V
P
T
Q
R
T
E
G
I
S
T
S
D
Site 23
S201
T
Q
R
T
E
G
I
S
T
S
D
I
I
T
R
Site 24
T202
Q
R
T
E
G
I
S
T
S
D
I
I
T
R
I
Site 25
S203
R
T
E
G
I
S
T
S
D
I
I
T
R
I
V
Site 26
T207
I
S
T
S
D
I
I
T
R
I
V
R
D
Y
D
Site 27
Y213
I
T
R
I
V
R
D
Y
D
V
Y
A
R
R
N
Site 28
Y216
I
V
R
D
Y
D
V
Y
A
R
R
N
L
Q
R
Site 29
Y225
R
R
N
L
Q
R
G
Y
T
A
K
E
L
N
V
Site 30
T226
R
N
L
Q
R
G
Y
T
A
K
E
L
N
V
S
Site 31
S233
T
A
K
E
L
N
V
S
F
I
N
E
K
R
Y
Site 32
S271
V
N
R
V
E
E
K
S
H
D
L
I
Q
K
W
Site 33
S307
K
Q
M
F
Q
E
R
S
S
R
M
L
Q
A
L
Site 34
S308
Q
M
F
Q
E
R
S
S
R
M
L
Q
A
L
S
Site 35
S315
S
R
M
L
Q
A
L
S
P
K
Q
S
P
V
S
CTP: phosphocholine cytidylyltransferase isoform B S315+S319 phosphosite-specific antibody AB-PN546#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-PN546
Site 36
S319
Q
A
L
S
P
K
Q
S
P
V
S
S
P
T
R
CTP: phosphocholine cytidylyltransferase isoform B S315+S319 phosphosite-specific antibody AB-PN546#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-PN546
Site 37
S322
S
P
K
Q
S
P
V
S
S
P
T
R
S
R
S
Site 38
S323
P
K
Q
S
P
V
S
S
P
T
R
S
R
S
P
Site 39
T325
Q
S
P
V
S
S
P
T
R
S
R
S
P
S
R
Site 40
S327
P
V
S
S
P
T
R
S
R
S
P
S
R
S
P
Site 41
S329
S
S
P
T
R
S
R
S
P
S
R
S
P
S
P
Site 42
S331
P
T
R
S
R
S
P
S
R
S
P
S
P
T
F
Site 43
S333
R
S
R
S
P
S
R
S
P
S
P
T
F
S
W
Site 44
S335
R
S
R
S
P
S
R
S
P
S
P
T
F
S
W
Site 45
T337
P
S
R
S
P
S
P
T
F
S
W
L
P
L
K
Site 46
S339
R
S
P
S
P
T
F
S
W
L
P
L
K
T
S
Site 47
T345
F
S
W
L
P
L
K
T
S
P
P
S
S
P
K
Site 48
S346
S
W
L
P
L
K
T
S
P
P
S
S
P
K
A
Site 49
S349
P
L
K
T
S
P
P
S
S
P
K
A
A
S
A
Site 50
S350
L
K
T
S
P
P
S
S
P
K
A
A
S
A
S
Site 51
S355
P
S
S
P
K
A
A
S
A
S
I
S
S
M
S
Site 52
S357
S
P
K
A
A
S
A
S
I
S
S
M
S
E
G
Site 53
S359
K
A
A
S
A
S
I
S
S
M
S
E
G
D
E
Site 54
S362
S
A
S
I
S
S
M
S
E
G
D
E
D
E
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation