PhosphoNET

           
Protein Info 
   
Short Name:  YTHDF2
Full Name:  YTH domain family protein 2
Alias:  CLL-associated antigen KW-14; HGRG8; High-glucose-regulated protein 8; High-glucose-regulated protein 8 homolog; NY-REN-2; Renal carcinoma antigen NY-REN-2; YTH domain family, member 2; YTHD2
Type:  Uncharacterized protein
Mass (Da):  62334
Number AA:  579
UniProt ID:  Q9Y5A9
International Prot ID:  IPI00306043
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:      Uniprot OncoNet
Molecular Function:      PhosphoSite+ KinaseNET
Biological Process:  GO:0002376  GO:0006955  GO:0006959 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S2______MSASSLLEQ
Site 2S5___MSASSLLEQRPK
Site 3S22GNKVQNGSVHQKDGL
Site 4Y37NDDDFEPYLSPQARP
Site 5S39DDFEPYLSPQARPNN
Site 6Y48QARPNNAYTAMSDSY
Site 7S52NNAYTAMSDSYLPSY
Site 8S54AYTAMSDSYLPSYYS
Site 9Y55YTAMSDSYLPSYYSP
Site 10S58MSDSYLPSYYSPSIG
Site 11Y59SDSYLPSYYSPSIGF
Site 12Y60DSYLPSYYSPSIGFS
Site 13S61SYLPSYYSPSIGFSY
Site 14S63LPSYYSPSIGFSYSL
Site 15S67YSPSIGFSYSLGEAA
Site 16S69PSIGFSYSLGEAAWS
Site 17S76SLGEAAWSTGGDTAM
Site 18T81AWSTGGDTAMPYLTS
Site 19Y85GGDTAMPYLTSYGQL
Site 20T87DTAMPYLTSYGQLSN
Site 21S88TAMPYLTSYGQLSNG
Site 22Y89AMPYLTSYGQLSNGE
Site 23S93LTSYGQLSNGEPHFL
Site 24S113GQPGALGSTPFLGQH
Site 25T114QPGALGSTPFLGQHG
Site 26S132FPSGIDFSAWGNNSS
Site 27S138FSAWGNNSSQGQSTQ
Site 28S139SAWGNNSSQGQSTQS
Site 29S143NNSSQGQSTQSSGYS
Site 30T144NSSQGQSTQSSGYSS
Site 31S146SQGQSTQSSGYSSNY
Site 32S147QGQSTQSSGYSSNYA
Site 33S150STQSSGYSSNYAYAP
Site 34S151TQSSGYSSNYAYAPS
Site 35Y153SSGYSSNYAYAPSSL
Site 36Y155GYSSNYAYAPSSLGG
Site 37S159NYAYAPSSLGGAMID
Site 38T230SNSLPPATIAPPKPA
Site 39S238IAPPKPASWADIASK
Site 40S244ASWADIASKPAKQQP
Site 41S262TKNGIAGSSLPPPPI
Site 42S263KNGIAGSSLPPPPIK
Site 43T277KHNMDIGTWDNKGPV
Site 44S303IGQPTQGSPQPVGQQ
Site 45S314VGQQANNSPPVAQAS
Site 46S321SPPVAQASVGQQTQP
Site 47S340PPQPAQLSVQQQAAQ
Site 48S359VAPRNRGSGFGHNGV
Site 49S374DGNGVGQSQAGSGST
Site 50S378VGQSQAGSGSTPSEP
Site 51S380QSQAGSGSTPSEPHP
Site 52T381SQAGSGSTPSEPHPV
Site 53S383AGSGSTPSEPHPVLE
Site 54S394PVLEKLRSINNYNPK
Site 55Y398KLRSINNYNPKDFDW
Site 56S417GRVFIIKSYSEDDIH
Site 57S419VFIIKSYSEDDIHRS
Site 58Y446NKRLDAAYRSMNGKG
Site 59S448RLDAAYRSMNGKGPV
Site 60Y479EMKSAVDYNTCAGVW
Site 61S508FVKDVPNSQLRHIRL
Site 62T524NNENKPVTNSRDTQE
Site 63T529PVTNSRDTQEVPLEK
Site 64S552ASYKHTTSIFDDFSH
Site 65S558TSIFDDFSHYEKRQE
Site 66Y560IFDDFSHYEKRQEEE
Site 67S569KRQEEEESVKKERQG
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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