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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
IPP
Full Name:
Actin-binding protein IPP
Alias:
Intracisternal A particle-promoted polypeptide;Kelch-like protein 27
Type:
Mass (Da):
65261
Number AA:
584
UniProt ID:
Q9Y573
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
D
C
P
K
A
A
D
S
P
F
S
S
D
K
H
Site 2
S15
K
A
A
D
S
P
F
S
S
D
K
H
A
Q
L
Site 3
S16
A
A
D
S
P
F
S
S
D
K
H
A
Q
L
I
Site 4
S47
Q
L
Q
V
G
Q
E
S
F
K
A
H
R
L
V
Site 5
S74
T
G
G
M
K
E
S
S
K
D
V
V
P
I
L
Site 6
S189
Q
L
I
K
I
L
R
S
E
E
L
S
I
E
D
Site 7
S193
I
L
R
S
E
E
L
S
I
E
D
E
Y
Q
V
Site 8
Y239
P
P
Q
R
L
L
K
Y
I
E
G
V
S
D
F
Site 9
T254
N
L
R
V
A
L
Q
T
L
L
K
E
Y
C
E
Site 10
Y259
L
Q
T
L
L
K
E
Y
C
E
V
C
K
S
P
Site 11
S273
P
K
E
N
K
F
C
S
F
L
Q
T
S
K
V
Site 12
T277
K
F
C
S
F
L
Q
T
S
K
V
R
P
R
K
Site 13
S278
F
C
S
F
L
Q
T
S
K
V
R
P
R
K
K
Site 14
Y289
P
R
K
K
A
R
K
Y
L
Y
A
V
G
G
Y
Site 15
Y291
K
K
A
R
K
Y
L
Y
A
V
G
G
Y
T
R
Site 16
Y296
Y
L
Y
A
V
G
G
Y
T
R
L
Q
G
G
R
Site 17
S305
R
L
Q
G
G
R
W
S
D
S
R
A
L
S
C
Site 18
S307
Q
G
G
R
W
S
D
S
R
A
L
S
C
V
E
Site 19
S311
W
S
D
S
R
A
L
S
C
V
E
R
F
D
T
Site 20
Y322
R
F
D
T
F
S
Q
Y
W
T
T
V
S
S
L
Site 21
T325
T
F
S
Q
Y
W
T
T
V
S
S
L
H
Q
A
Site 22
S328
Q
Y
W
T
T
V
S
S
L
H
Q
A
R
S
G
Site 23
S354
A
I
G
G
E
K
D
S
M
I
F
D
C
T
E
Site 24
T406
V
G
A
E
I
G
N
T
I
E
R
F
D
P
D
Site 25
S454
N
E
G
I
E
L
R
S
F
E
V
Y
D
P
L
Site 26
Y458
E
L
R
S
F
E
V
Y
D
P
L
S
K
R
W
Site 27
S462
F
E
V
Y
D
P
L
S
K
R
W
S
P
L
P
Site 28
S466
D
P
L
S
K
R
W
S
P
L
P
P
M
G
T
Site 29
T473
S
P
L
P
P
M
G
T
R
R
A
Y
L
G
V
Site 30
Y488
A
A
L
N
D
C
I
Y
S
V
G
G
W
N
E
Site 31
S507
L
H
T
V
E
K
Y
S
F
E
E
E
K
W
V
Site 32
S538
V
N
G
L
L
Y
V
S
G
G
R
S
S
S
H
Site 33
S542
L
Y
V
S
G
G
R
S
S
S
H
D
F
L
A
Site 34
S543
Y
V
S
G
G
R
S
S
S
H
D
F
L
A
P
Site 35
S544
V
S
G
G
R
S
S
S
H
D
F
L
A
P
G
Site 36
S555
L
A
P
G
T
L
D
S
V
E
V
Y
N
P
H
Site 37
Y559
T
L
D
S
V
E
V
Y
N
P
H
S
D
T
W
Site 38
T567
N
P
H
S
D
T
W
T
E
I
G
N
M
I
T
Site 39
T574
T
E
I
G
N
M
I
T
S
R
C
E
G
G
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation