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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
LRRC42
Full Name:
Leucine-rich repeat-containing protein 42
Alias:
LRC42; MGC8974
Type:
Mass (Da):
48571
Number AA:
428
UniProt ID:
Q9Y546
International Prot ID:
IPI00395724
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y17
H
L
D
P
G
P
I
Y
M
R
E
N
G
Q
L
Site 2
S36
L
A
L
D
G
V
R
S
S
L
Q
K
P
R
P
Site 3
S37
A
L
D
G
V
R
S
S
L
Q
K
P
R
P
F
Site 4
T63
C
M
N
R
E
D
D
T
A
R
K
E
K
T
D
Site 5
T69
D
T
A
R
K
E
K
T
D
H
F
I
F
T
Y
Site 6
T75
K
T
D
H
F
I
F
T
Y
T
R
E
G
N
L
Site 7
Y76
T
D
H
F
I
F
T
Y
T
R
E
G
N
L
R
Site 8
Y84
T
R
E
G
N
L
R
Y
S
A
K
S
L
F
S
Site 9
S85
R
E
G
N
L
R
Y
S
A
K
S
L
F
S
L
Site 10
S106
D
N
V
D
H
I
D
S
L
I
G
F
P
E
Q
Site 11
S120
Q
I
A
E
K
L
F
S
A
A
E
A
R
Q
K
Site 12
S163
R
N
R
Y
L
V
I
S
E
K
L
E
E
I
K
Site 13
S171
E
K
L
E
E
I
K
S
F
R
E
L
T
C
L
Site 14
T196
H
E
L
L
E
H
L
T
N
E
A
L
S
S
V
Site 15
S202
L
T
N
E
A
L
S
S
V
T
Q
L
H
L
K
Site 16
T222
D
A
G
V
R
K
M
T
A
P
V
R
V
M
K
Site 17
T236
K
R
G
L
E
N
L
T
L
L
D
L
S
C
N
Site 18
S241
N
L
T
L
L
D
L
S
C
N
P
E
I
T
D
Site 19
T275
T
G
L
K
D
I
K
T
V
K
H
K
L
Q
T
Site 20
T318
V
L
Q
W
E
R
V
T
A
E
A
V
K
P
R
Site 21
T327
E
A
V
K
P
R
E
T
S
E
P
R
A
A
A
Site 22
S328
A
V
K
P
R
E
T
S
E
P
R
A
A
A
Q
Site 23
Y338
R
A
A
A
Q
R
F
Y
G
K
R
S
R
A
E
Site 24
S342
Q
R
F
Y
G
K
R
S
R
A
E
A
P
L
K
Site 25
T355
L
K
C
P
L
A
D
T
H
M
N
S
S
E
K
Site 26
S359
L
A
D
T
H
M
N
S
S
E
K
L
Q
F
Y
Site 27
Y366
S
S
E
K
L
Q
F
Y
K
E
K
A
P
D
C
Site 28
S384
V
L
K
H
E
A
I
S
S
Q
E
S
K
K
S
Site 29
S385
L
K
H
E
A
I
S
S
Q
E
S
K
K
S
K
Site 30
S388
E
A
I
S
S
Q
E
S
K
K
S
K
K
R
P
Site 31
S391
S
S
Q
E
S
K
K
S
K
K
R
P
F
E
E
Site 32
S399
K
K
R
P
F
E
E
S
E
T
E
Q
N
N
S
Site 33
T401
R
P
F
E
E
S
E
T
E
Q
N
N
S
S
Q
Site 34
S406
S
E
T
E
Q
N
N
S
S
Q
P
S
K
Q
K
Site 35
S407
E
T
E
Q
N
N
S
S
Q
P
S
K
Q
K
Y
Site 36
S410
Q
N
N
S
S
Q
P
S
K
Q
K
Y
V
C
L
Site 37
Y414
S
Q
P
S
K
Q
K
Y
V
C
L
A
V
E
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation