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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SAMM50
Full Name:
Sorting and assembly machinery component 50 homolog
Alias:
Transformation-related gene 3 protein
Type:
Mass (Da):
51976
Number AA:
469
UniProt ID:
Q9Y512
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
G
T
V
H
A
R
S
L
E
P
L
P
S
S
Site 2
S14
R
S
L
E
P
L
P
S
S
G
P
D
F
G
G
Site 3
S15
S
L
E
P
L
P
S
S
G
P
D
F
G
G
L
Site 4
S83
L
I
E
V
M
R
K
S
H
E
A
R
E
K
L
Site 5
T129
V
T
E
L
R
R
L
T
G
S
Y
N
T
M
V
Site 6
S131
E
L
R
R
L
T
G
S
Y
N
T
M
V
G
N
Site 7
Y132
L
R
R
L
T
G
S
Y
N
T
M
V
G
N
N
Site 8
T160
L
G
R
A
E
K
V
T
F
Q
F
S
Y
G
T
Site 9
S164
E
K
V
T
F
Q
F
S
Y
G
T
K
E
T
S
Site 10
Y165
K
V
T
F
Q
F
S
Y
G
T
K
E
T
S
Y
Site 11
Y172
Y
G
T
K
E
T
S
Y
G
L
S
F
F
K
P
Site 12
S175
K
E
T
S
Y
G
L
S
F
F
K
P
R
P
G
Site 13
S189
G
N
F
E
R
N
F
S
V
N
L
Y
K
V
T
Site 14
Y193
R
N
F
S
V
N
L
Y
K
V
T
G
Q
F
P
Site 15
S202
V
T
G
Q
F
P
W
S
S
L
R
E
T
D
R
Site 16
S203
T
G
Q
F
P
W
S
S
L
R
E
T
D
R
G
Site 17
T207
P
W
S
S
L
R
E
T
D
R
G
M
S
A
E
Site 18
S212
R
E
T
D
R
G
M
S
A
E
Y
S
F
P
I
Site 19
Y215
D
R
G
M
S
A
E
Y
S
F
P
I
W
K
T
Site 20
S216
R
G
M
S
A
E
Y
S
F
P
I
W
K
T
S
Site 21
S243
G
C
L
S
R
T
A
S
F
A
V
R
K
E
S
Site 22
S250
S
F
A
V
R
K
E
S
G
H
S
L
K
S
S
Site 23
S253
V
R
K
E
S
G
H
S
L
K
S
S
L
S
H
Site 24
S256
E
S
G
H
S
L
K
S
S
L
S
H
A
M
V
Site 25
S259
H
S
L
K
S
S
L
S
H
A
M
V
I
D
S
Site 26
S266
S
H
A
M
V
I
D
S
R
N
S
S
I
L
P
Site 27
S269
M
V
I
D
S
R
N
S
S
I
L
P
R
R
G
Site 28
S270
V
I
D
S
R
N
S
S
I
L
P
R
R
G
A
Site 29
Y288
V
N
Q
E
L
A
G
Y
T
G
G
D
V
S
F
Site 30
S294
G
Y
T
G
G
D
V
S
F
I
K
E
D
F
E
Site 31
S331
V
P
I
G
D
K
P
S
S
I
A
D
R
F
Y
Site 32
S332
P
I
G
D
K
P
S
S
I
A
D
R
F
Y
L
Site 33
Y338
S
S
I
A
D
R
F
Y
L
G
G
P
T
S
I
Site 34
S344
F
Y
L
G
G
P
T
S
I
R
G
F
S
M
H
Site 35
S349
P
T
S
I
R
G
F
S
M
H
S
I
G
P
Q
Site 36
S352
I
R
G
F
S
M
H
S
I
G
P
Q
S
E
G
Site 37
S357
M
H
S
I
G
P
Q
S
E
G
D
Y
L
G
G
Site 38
Y361
G
P
Q
S
E
G
D
Y
L
G
G
E
A
Y
W
Site 39
Y367
D
Y
L
G
G
E
A
Y
W
A
G
G
L
H
L
Site 40
Y375
W
A
G
G
L
H
L
Y
T
P
L
P
F
R
P
Site 41
T376
A
G
G
L
H
L
Y
T
P
L
P
F
R
P
G
Site 42
Y407
G
N
L
C
N
L
N
Y
G
E
G
P
K
A
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation