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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ARIH1
Full Name:
Protein ariadne-1 homolog
Alias:
H7-AP2;HHARI;Monocyte protein 6;UbcH7-binding protein;UbcM4-interacting protein;Ubiquitin-conjugating enzyme E2-binding protein 1
Type:
Mass (Da):
64118
Number AA:
557
UniProt ID:
Q9Y4X5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y7
_
M
D
S
D
E
G
Y
N
Y
E
F
D
E
D
Site 2
Y9
D
S
D
E
G
Y
N
Y
E
F
D
E
D
E
E
Site 3
S18
F
D
E
D
E
E
C
S
E
E
D
S
G
A
E
Site 4
S22
E
E
C
S
E
E
D
S
G
A
E
E
E
E
D
Site 5
T39
D
D
E
P
D
D
D
T
L
D
L
G
E
V
E
Site 6
T66
D
G
L
L
C
G
E
T
G
G
G
G
G
S
A
Site 7
S72
E
T
G
G
G
G
G
S
A
L
G
P
G
G
G
Site 8
Y99
G
H
E
Q
E
E
D
Y
R
Y
E
V
L
T
A
Site 9
Y101
E
Q
E
E
D
Y
R
Y
E
V
L
T
A
E
Q
Site 10
T105
D
Y
R
Y
E
V
L
T
A
E
Q
I
L
Q
H
Site 11
Y149
K
E
K
L
M
E
R
Y
F
D
G
N
L
E
K
Site 12
S170
V
I
N
P
S
K
K
S
R
T
R
Q
M
N
T
Site 13
S179
T
R
Q
M
N
T
R
S
S
A
Q
D
M
P
C
Site 14
S180
R
Q
M
N
T
R
S
S
A
Q
D
M
P
C
Q
Site 15
Y197
Y
L
N
Y
P
N
S
Y
F
T
G
L
E
C
G
Site 16
T250
N
T
V
M
R
L
I
T
D
S
K
V
K
L
K
Site 17
S252
V
M
R
L
I
T
D
S
K
V
K
L
K
Y
Q
Site 18
Y258
D
S
K
V
K
L
K
Y
Q
H
L
I
T
N
S
Site 19
Y289
H
H
V
V
K
V
Q
Y
P
D
A
K
P
V
R
Site 20
S331
I
K
K
C
D
D
D
S
E
T
S
N
W
I
A
Site 21
T350
E
C
P
K
C
H
V
T
I
E
K
D
G
G
C
Site 22
Y387
E
P
H
G
S
A
W
Y
N
C
N
R
Y
N
E
Site 23
Y414
S
R
A
A
L
Q
R
Y
L
F
Y
C
N
R
Y
Site 24
Y435
L
R
F
E
H
K
L
Y
A
Q
V
K
Q
K
M
Site 25
T502
Q
A
D
L
E
N
A
T
E
V
L
S
G
Y
L
Site 26
Y508
A
T
E
V
L
S
G
Y
L
E
R
D
I
S
Q
Site 27
S514
G
Y
L
E
R
D
I
S
Q
D
S
L
Q
D
I
Site 28
S517
E
R
D
I
S
Q
D
S
L
Q
D
I
K
Q
K
Site 29
Y529
K
Q
K
V
Q
D
K
Y
R
Y
C
E
S
R
R
Site 30
S534
D
K
Y
R
Y
C
E
S
R
R
R
V
L
L
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation