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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TTLL3
Full Name:
Tubulin monoglycylase TTLL3
Alias:
HOTTL;Tubulin--tyrosine ligase-like protein 3
Type:
Mass (Da):
87414
Number AA:
772
UniProt ID:
Q9Y4R7
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y10
R
L
R
N
A
K
I
Y
V
E
R
A
V
K
Q
Site 2
S48
E
K
K
M
V
H
R
S
G
P
T
L
L
P
P
Site 3
S61
P
P
Q
K
D
L
D
S
S
A
M
G
D
S
D
Site 4
S67
D
S
S
A
M
G
D
S
D
T
T
E
D
E
D
Site 5
T69
S
A
M
G
D
S
D
T
T
E
D
E
D
E
D
Site 6
S84
E
D
E
E
F
Q
P
S
Q
L
F
D
F
D
D
Site 7
Y131
N
S
F
F
P
R
C
Y
C
L
G
A
E
D
D
Site 8
S165
V
V
K
S
E
W
K
S
Y
P
I
Q
A
V
E
Site 9
Y166
V
K
S
E
W
K
S
Y
P
I
Q
A
V
E
E
Site 10
S176
Q
A
V
E
E
E
A
S
G
D
K
Q
P
K
K
Site 11
S192
E
K
N
P
V
L
V
S
P
E
F
V
D
E
A
Site 12
Y224
K
D
L
E
A
P
L
Y
L
T
P
E
G
W
S
Site 13
Y237
W
S
L
F
L
Q
R
Y
Y
Q
V
V
H
E
G
Site 14
Y238
S
L
F
L
Q
R
Y
Y
Q
V
V
H
E
G
A
Site 15
T252
A
E
L
R
H
L
D
T
Q
V
Q
R
C
E
D
Site 16
S288
I
V
K
P
G
A
K
S
R
G
R
G
I
M
C
Site 17
Y358
V
W
F
Y
R
D
S
Y
I
R
F
S
T
Q
P
Site 18
S362
R
D
S
Y
I
R
F
S
T
Q
P
F
S
L
K
Site 19
T363
D
S
Y
I
R
F
S
T
Q
P
F
S
L
K
N
Site 20
S367
R
F
S
T
Q
P
F
S
L
K
N
L
D
N
S
Site 21
S374
S
L
K
N
L
D
N
S
V
H
L
C
N
N
S
Site 22
S439
V
I
H
A
L
Q
T
S
Q
D
T
V
Q
C
R
Site 23
T442
A
L
Q
T
S
Q
D
T
V
Q
C
R
K
A
S
Site 24
S449
T
V
Q
C
R
K
A
S
F
E
L
Y
G
A
D
Site 25
T509
M
L
D
R
N
C
D
T
G
A
F
E
L
I
Y
Site 26
T559
R
P
A
V
P
L
L
T
Q
R
G
S
G
E
A
Site 27
S563
P
L
L
T
Q
R
G
S
G
E
A
R
H
H
F
Site 28
S572
E
A
R
H
H
F
P
S
L
H
T
K
A
Q
L
Site 29
S581
H
T
K
A
Q
L
P
S
P
H
V
L
R
H
Q
Site 30
S597
Q
V
L
R
R
Q
H
S
K
L
V
G
T
K
A
Site 31
S680
R
S
R
P
K
A
N
S
R
P
D
C
D
K
P
Site 32
T708
K
P
L
P
L
V
G
T
F
Q
R
R
R
G
L
Site 33
T736
T
A
L
V
L
D
P
T
P
N
K
K
K
Q
V
Site 34
Y745
N
K
K
K
Q
V
K
Y
L
G
L
D
S
I
A
Site 35
T765
V
D
G
A
R
P
C
T
P
G
S
T
A
R
A
Site 36
S768
A
R
P
C
T
P
G
S
T
A
R
A
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation