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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
WIPI2
Full Name:
WD repeat domain phosphoinositide-interacting protein 2
Alias:
Atg21; CGI-50; FLJ12979; FLJ14217; FLJ42984; WD repeat domain phosphoinositide-interacting protein 2: WIPI49-like protein 2: WD repeat domain phosphoinositide-interacting protein 2: WIPI49-like protein 2; WD repeat domain, phosphoinositide interacting 2; WIPI-2
Type:
Mass (Da):
49408
Number AA:
454
UniProt ID:
Q9Y4P8
International Prot ID:
Isoform1 - IPI00024056
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0043234
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T25
A
N
F
N
Q
D
N
T
E
V
K
G
A
S
R
Site 2
Y53
A
V
G
S
K
S
G
Y
K
F
F
S
L
S
S
Site 3
S57
K
S
G
Y
K
F
F
S
L
S
S
V
D
K
L
Site 4
S59
G
Y
K
F
F
S
L
S
S
V
D
K
L
E
Q
Site 5
Y68
V
D
K
L
E
Q
I
Y
E
C
T
D
T
E
D
Site 6
Y113
K
G
T
E
I
C
N
Y
S
Y
S
N
T
I
L
Site 7
T118
C
N
Y
S
Y
S
N
T
I
L
A
V
K
L
N
Site 8
T150
R
D
M
K
V
L
H
T
I
R
E
T
P
P
N
Site 9
T154
V
L
H
T
I
R
E
T
P
P
N
P
A
G
L
Site 10
Y172
S
I
N
N
D
N
C
Y
L
A
Y
P
G
S
A
Site 11
Y175
N
D
N
C
Y
L
A
Y
P
G
S
A
T
I
G
Site 12
S221
G
T
K
L
A
T
A
S
E
K
G
T
V
I
R
Site 13
S264
S
M
D
G
M
F
L
S
A
S
S
N
T
E
T
Site 14
S266
D
G
M
F
L
S
A
S
S
N
T
E
T
V
H
Site 15
T271
S
A
S
S
N
T
E
T
V
H
I
F
K
L
E
Site 16
T279
V
H
I
F
K
L
E
T
V
K
E
K
P
P
E
Site 17
T290
K
P
P
E
E
P
T
T
W
T
G
Y
F
G
K
Site 18
T292
P
E
E
P
T
T
W
T
G
Y
F
G
K
V
L
Site 19
Y294
E
P
T
T
W
T
G
Y
F
G
K
V
L
M
A
Site 20
S308
A
S
T
S
Y
L
P
S
Q
V
T
E
M
F
N
Site 21
Y355
G
A
A
D
G
Y
L
Y
M
Y
N
L
D
P
Q
Site 22
Y357
A
D
G
Y
L
Y
M
Y
N
L
D
P
Q
E
G
Site 23
S378
K
Q
H
R
L
D
G
S
L
E
T
T
N
E
I
Site 24
T382
L
D
G
S
L
E
T
T
N
E
I
L
D
S
A
Site 25
S388
T
T
N
E
I
L
D
S
A
S
H
D
C
P
L
Site 26
S390
N
E
I
L
D
S
A
S
H
D
C
P
L
V
T
Site 27
T408
G
A
A
A
G
K
G
T
Y
V
P
S
S
P
T
Site 28
Y409
A
A
A
G
K
G
T
Y
V
P
S
S
P
T
R
Site 29
S412
G
K
G
T
Y
V
P
S
S
P
T
R
L
A
Y
Site 30
S413
K
G
T
Y
V
P
S
S
P
T
R
L
A
Y
T
Site 31
T415
T
Y
V
P
S
S
P
T
R
L
A
Y
T
D
D
Site 32
Y419
S
S
P
T
R
L
A
Y
T
D
D
L
G
A
V
Site 33
S436
A
C
L
E
D
E
A
S
A
L
R
L
D
E
D
Site 34
S444
A
L
R
L
D
E
D
S
E
H
P
P
M
I
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation