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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PLXND1
Full Name:
Plexin-D1
Alias:
KIAA0620; PLEXD1; Plexin D1; Plexin-D1; PLXD1
Type:
Receptor, misc.
Mass (Da):
212095
Number AA:
1925
UniProt ID:
Q9Y4D7
International Prot ID:
IPI00412492
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
GO:0005886
GO:0016020
Uniprot
OncoNet
Molecular Function:
GO:0004871
GO:0004872
GO:0004888
PhosphoSite+
KinaseNET
Biological Process:
GO:0001569
GO:0001763
GO:0007154
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S19
S
A
R
A
A
A
A
S
P
P
P
F
Q
T
P
Site 2
T25
A
S
P
P
P
F
Q
T
P
P
R
C
P
V
P
Site 3
S838
R
P
A
R
F
L
D
S
P
E
P
M
T
V
M
Site 4
S1075
N
P
V
I
T
A
I
S
P
R
R
S
P
V
S
Site 5
S1079
T
A
I
S
P
R
R
S
P
V
S
G
G
R
T
Site 6
T1088
V
S
G
G
R
T
I
T
V
A
G
E
R
F
H
Site 7
Y1303
K
S
R
R
A
E
R
Y
W
Q
K
T
L
L
Q
Site 8
S1316
L
Q
M
E
E
M
E
S
Q
I
R
E
E
I
R
Site 9
T1334
A
E
L
Q
T
D
M
T
D
L
T
K
E
L
N
Site 10
T1337
Q
T
D
M
T
D
L
T
K
E
L
N
R
S
Q
Site 11
S1343
L
T
K
E
L
N
R
S
Q
G
I
P
F
L
E
Site 12
Y1351
Q
G
I
P
F
L
E
Y
K
H
F
V
T
R
T
Site 13
T1358
Y
K
H
F
V
T
R
T
F
F
P
K
C
S
S
Site 14
S1365
T
F
F
P
K
C
S
S
L
Y
E
E
R
Y
V
Site 15
Y1367
F
P
K
C
S
S
L
Y
E
E
R
Y
V
L
P
Site 16
Y1371
S
S
L
Y
E
E
R
Y
V
L
P
S
Q
T
L
Site 17
S1375
E
E
R
Y
V
L
P
S
Q
T
L
N
S
Q
G
Site 18
T1377
R
Y
V
L
P
S
Q
T
L
N
S
Q
G
S
S
Site 19
S1380
L
P
S
Q
T
L
N
S
Q
G
S
S
Q
A
Q
Site 20
S1384
T
L
N
S
Q
G
S
S
Q
A
Q
E
T
H
P
Site 21
S1411
P
N
M
E
E
G
I
S
L
F
S
S
L
L
N
Site 22
S1415
E
G
I
S
L
F
S
S
L
L
N
N
K
H
F
Site 23
Y1459
L
H
G
K
L
E
Y
Y
T
S
I
M
K
E
L
Site 24
T1486
P
K
L
M
L
R
R
T
E
S
V
V
E
K
M
Site 25
T1534
K
G
S
I
D
A
I
T
G
K
A
R
Y
T
L
Site 26
T1540
I
T
G
K
A
R
Y
T
L
N
E
E
W
L
L
Site 27
S1561
K
P
R
N
L
N
V
S
F
Q
G
C
G
M
D
Site 28
S1569
F
Q
G
C
G
M
D
S
L
S
V
R
A
M
D
Site 29
S1571
G
C
G
M
D
S
L
S
V
R
A
M
D
T
D
Site 30
T1579
V
R
A
M
D
T
D
T
L
T
Q
V
K
E
K
Site 31
T1581
A
M
D
T
D
T
L
T
Q
V
K
E
K
I
L
Site 32
T1615
L
E
W
F
A
S
S
T
Q
S
Y
I
L
R
D
Site 33
S1617
W
F
A
S
S
T
Q
S
Y
I
L
R
D
L
D
Site 34
Y1618
F
A
S
S
T
Q
S
Y
I
L
R
D
L
D
D
Site 35
T1626
I
L
R
D
L
D
D
T
S
V
V
E
D
G
R
Site 36
S1627
L
R
D
L
D
D
T
S
V
V
E
D
G
R
K
Site 37
T1638
D
G
R
K
K
L
N
T
L
A
H
Y
K
I
P
Site 38
Y1642
K
L
N
T
L
A
H
Y
K
I
P
E
G
A
S
Site 39
S1653
E
G
A
S
L
A
M
S
L
I
D
K
K
D
N
Site 40
T1661
L
I
D
K
K
D
N
T
L
G
R
V
K
D
L
Site 41
T1670
G
R
V
K
D
L
D
T
E
K
Y
F
H
L
V
Site 42
Y1673
K
D
L
D
T
E
K
Y
F
H
L
V
L
P
T
Site 43
S1689
E
L
A
E
P
K
K
S
H
R
Q
S
H
R
K
Site 44
S1693
P
K
K
S
H
R
Q
S
H
R
K
K
V
L
P
Site 45
S1709
I
Y
L
T
R
L
L
S
T
K
G
T
L
Q
K
Site 46
T1713
R
L
L
S
T
K
G
T
L
Q
K
F
L
D
D
Site 47
S1727
D
L
F
K
A
I
L
S
I
R
E
D
K
P
P
Site 48
Y1739
K
P
P
L
A
V
K
Y
F
F
D
F
L
E
E
Site 49
S1754
Q
A
E
K
R
G
I
S
D
P
D
T
L
H
I
Site 50
T1758
R
G
I
S
D
P
D
T
L
H
I
W
K
T
N
Site 51
T1764
D
T
L
H
I
W
K
T
N
S
L
P
L
R
F
Site 52
S1817
D
L
Q
L
G
K
D
S
P
T
N
K
L
L
Y
Site 53
Y1824
S
P
T
N
K
L
L
Y
A
K
E
I
P
E
Y
Site 54
Y1831
Y
A
K
E
I
P
E
Y
R
K
I
V
Q
R
Y
Site 55
Y1839
R
K
I
V
Q
R
Y
Y
K
Q
I
Q
D
M
T
Site 56
T1846
Y
K
Q
I
Q
D
M
T
P
L
S
E
Q
E
M
Site 57
S1849
I
Q
D
M
T
P
L
S
E
Q
E
M
N
A
H
Site 58
Y1864
L
A
E
E
S
R
K
Y
Q
N
E
F
N
T
N
Site 59
Y1880
A
M
A
E
I
Y
K
Y
A
K
R
Y
R
P
Q
Site 60
T1897
A
A
L
E
A
N
P
T
A
R
R
T
Q
L
Q
Site 61
T1901
A
N
P
T
A
R
R
T
Q
L
Q
H
K
F
E
Site 62
Y1919
A
L
M
E
D
N
I
Y
E
C
Y
S
E
A
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation