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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF175
Full Name:
Zinc finger protein 175
Alias:
OTK18; Zinc finger protein OTK18; ZN175
Type:
Mass (Da):
81610
Number AA:
UniProt ID:
Q9Y473
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003700
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0009615
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
P
A
D
V
N
L
S
Q
K
P
Q
V
L
G
Site 2
S22
G
P
E
K
Q
D
G
S
C
E
A
S
V
S
F
Site 3
S26
Q
D
G
S
C
E
A
S
V
S
F
E
D
V
T
Site 4
S28
G
S
C
E
A
S
V
S
F
E
D
V
T
V
D
Site 5
T33
S
V
S
F
E
D
V
T
V
D
F
S
R
E
E
Site 6
S37
E
D
V
T
V
D
F
S
R
E
E
W
Q
Q
L
Site 7
Y52
D
P
A
Q
R
C
L
Y
R
D
V
M
L
E
L
Site 8
S93
R
V
E
E
A
E
V
S
H
Q
R
C
Q
E
R
Site 9
S112
E
I
P
Q
K
E
I
S
K
K
A
S
F
Q
K
Site 10
S116
K
E
I
S
K
K
A
S
F
Q
K
D
M
V
G
Site 11
S130
G
E
F
T
R
D
G
S
W
C
S
I
L
E
E
Site 12
S133
T
R
D
G
S
W
C
S
I
L
E
E
L
R
L
Site 13
T145
L
R
L
D
A
D
R
T
K
K
D
E
Q
N
Q
Site 14
T166
S
A
F
F
N
K
K
T
L
N
T
E
S
N
C
Site 15
S171
K
K
T
L
N
T
E
S
N
C
E
Y
K
D
P
Site 16
Y175
N
T
E
S
N
C
E
Y
K
D
P
G
K
M
I
Site 17
S190
R
T
R
P
H
L
A
S
S
Q
K
Q
P
Q
K
Site 18
S191
T
R
P
H
L
A
S
S
Q
K
Q
P
Q
K
C
Site 19
T220
G
Q
N
E
S
N
D
T
E
Q
L
D
D
V
V
Site 20
S229
Q
L
D
D
V
V
G
S
G
Q
L
F
S
H
S
Site 21
S234
V
G
S
G
Q
L
F
S
H
S
S
S
D
A
C
Site 22
S236
S
G
Q
L
F
S
H
S
S
S
D
A
C
S
K
Site 23
S237
G
Q
L
F
S
H
S
S
S
D
A
C
S
K
N
Site 24
S238
Q
L
F
S
H
S
S
S
D
A
C
S
K
N
I
Site 25
S242
H
S
S
S
D
A
C
S
K
N
I
H
T
G
E
Site 26
T250
K
N
I
H
T
G
E
T
F
C
K
G
N
Q
C
Site 27
S282
Q
K
K
P
D
G
C
S
E
C
G
G
S
F
T
Site 28
S287
G
C
S
E
C
G
G
S
F
T
Q
K
S
H
L
Site 29
T289
S
E
C
G
G
S
F
T
Q
K
S
H
L
F
A
Site 30
S292
G
G
S
F
T
Q
K
S
H
L
F
A
Q
Q
R
Site 31
S302
F
A
Q
Q
R
I
H
S
V
G
N
L
H
E
C
Site 32
S323
F
M
P
Q
L
K
L
S
V
Y
L
T
D
H
T
Site 33
Y325
P
Q
L
K
L
S
V
Y
L
T
D
H
T
G
D
Site 34
T327
L
K
L
S
V
Y
L
T
D
H
T
G
D
I
P
Site 35
S348
G
K
V
F
I
Q
R
S
E
L
L
T
H
Q
K
Site 36
T352
I
Q
R
S
E
L
L
T
H
Q
K
T
H
T
R
Site 37
T356
E
L
L
T
H
Q
K
T
H
T
R
K
K
P
Y
Site 38
S377
K
A
F
F
Q
M
L
S
L
F
R
H
Q
R
T
Site 39
T384
S
L
F
R
H
Q
R
T
H
S
R
E
K
L
Y
Site 40
S386
F
R
H
Q
R
T
H
S
R
E
K
L
Y
E
C
Site 41
Y391
T
H
S
R
E
K
L
Y
E
C
S
E
C
G
K
Site 42
S394
R
E
K
L
Y
E
C
S
E
C
G
K
G
F
S
Site 43
S401
S
E
C
G
K
G
F
S
Q
N
S
T
L
I
I
Site 44
S404
G
K
G
F
S
Q
N
S
T
L
I
I
H
Q
K
Site 45
T405
K
G
F
S
Q
N
S
T
L
I
I
H
Q
K
I
Site 46
Y419
I
H
T
G
E
R
Q
Y
A
C
S
E
C
G
K
Site 47
S422
G
E
R
Q
Y
A
C
S
E
C
G
K
A
F
T
Site 48
T429
S
E
C
G
K
A
F
T
Q
K
S
T
L
S
L
Site 49
S432
G
K
A
F
T
Q
K
S
T
L
S
L
H
Q
R
Site 50
S435
F
T
Q
K
S
T
L
S
L
H
Q
R
I
H
S
Site 51
S442
S
L
H
Q
R
I
H
S
G
Q
K
S
Y
V
C
Site 52
Y447
I
H
S
G
Q
K
S
Y
V
C
I
E
C
G
Q
Site 53
T470
I
V
H
Q
R
S
H
T
G
E
K
P
Y
Q
C
Site 54
Y475
S
H
T
G
E
K
P
Y
Q
C
H
N
C
G
K
Site 55
S486
N
C
G
K
S
F
I
S
K
S
Q
L
D
I
H
Site 56
S488
G
K
S
F
I
S
K
S
Q
L
D
I
H
H
R
Site 57
T498
D
I
H
H
R
I
H
T
G
E
K
P
Y
E
C
Site 58
Y503
I
H
T
G
E
K
P
Y
E
C
S
D
C
G
K
Site 59
S506
G
E
K
P
Y
E
C
S
D
C
G
K
T
F
T
Site 60
T511
E
C
S
D
C
G
K
T
F
T
Q
K
S
H
L
Site 61
T513
S
D
C
G
K
T
F
T
Q
K
S
H
L
N
I
Site 62
S544
G
K
A
F
N
Q
K
S
I
L
S
M
H
Q
R
Site 63
T554
S
M
H
Q
R
I
H
T
G
E
K
P
Y
K
C
Site 64
Y559
I
H
T
G
E
K
P
Y
K
C
S
E
C
G
K
Site 65
S562
G
E
K
P
Y
K
C
S
E
C
G
K
A
F
T
Site 66
S572
G
K
A
F
T
S
K
S
Q
F
K
E
H
Q
R
Site 67
T582
K
E
H
Q
R
I
H
T
G
E
K
P
Y
V
C
Site 68
Y587
I
H
T
G
E
K
P
Y
V
C
T
E
C
G
K
Site 69
Y618
R
E
R
P
F
V
C
Y
K
C
G
K
A
F
V
Site 70
S628
G
K
A
F
V
Q
K
S
E
L
I
T
H
Q
R
Site 71
T632
V
Q
K
S
E
L
I
T
H
Q
R
T
H
M
G
Site 72
Y643
T
H
M
G
E
K
P
Y
E
C
L
D
C
G
K
Site 73
S651
E
C
L
D
C
G
K
S
F
S
K
K
P
Q
L
Site 74
S653
L
D
C
G
K
S
F
S
K
K
P
Q
L
K
V
Site 75
T666
K
V
H
Q
R
I
H
T
G
E
R
P
Y
V
C
Site 76
Y671
I
H
T
G
E
R
P
Y
V
C
S
E
C
G
K
Site 77
T694
N
K
H
Q
T
T
H
T
R
D
K
S
Y
K
C
Site 78
S698
T
T
H
T
R
D
K
S
Y
K
C
S
Y
S
V
Site 79
Y699
T
H
T
R
D
K
S
Y
K
C
S
Y
S
V
K
Site 80
S702
R
D
K
S
Y
K
C
S
Y
S
V
K
G
F
T
Site 81
Y703
D
K
S
Y
K
C
S
Y
S
V
K
G
F
T
K
Site 82
S704
K
S
Y
K
C
S
Y
S
V
K
G
F
T
K
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation