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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NOSIP
Full Name:
Nitric oxide synthase-interacting protein
Alias:
CGI-25; ENOS interacting protein; ENOS-interacting protein
Type:
Mass (Da):
33172
Number AA:
301
UniProt ID:
Q9Y314
International Prot ID:
IPI00006408
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005829
GO:0005634
GO:0000151
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0004842
PhosphoSite+
KinaseNET
Biological Process:
GO:0051001
GO:0016567
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y14
N
C
T
A
G
A
V
Y
T
Y
H
E
K
K
K
Site 2
T15
C
T
A
G
A
V
Y
T
Y
H
E
K
K
K
D
Site 3
Y16
T
A
G
A
V
Y
T
Y
H
E
K
K
K
D
T
Site 4
Y28
K
D
T
A
A
S
G
Y
G
T
Q
N
I
R
L
Site 5
T30
T
A
A
S
G
Y
G
T
Q
N
I
R
L
S
R
Site 6
S36
G
T
Q
N
I
R
L
S
R
D
A
V
K
D
F
Site 7
T59
P
C
H
D
P
V
V
T
P
D
G
Y
L
Y
E
Site 8
Y63
P
V
V
T
P
D
G
Y
L
Y
E
R
E
A
I
Site 9
Y65
V
T
P
D
G
Y
L
Y
E
R
E
A
I
L
E
Site 10
Y88
I
A
R
Q
M
K
A
Y
E
K
Q
R
G
T
R
Site 11
T94
A
Y
E
K
Q
R
G
T
R
R
E
E
Q
K
E
Site 12
S107
K
E
L
Q
R
A
A
S
Q
D
H
V
R
G
F
Site 13
S119
R
G
F
L
E
K
E
S
A
I
V
S
R
P
L
Site 14
S123
E
K
E
S
A
I
V
S
R
P
L
N
P
F
T
Site 15
T130
S
R
P
L
N
P
F
T
A
K
A
L
S
G
T
Site 16
S135
P
F
T
A
K
A
L
S
G
T
S
P
D
D
V
Site 17
T137
T
A
K
A
L
S
G
T
S
P
D
D
V
Q
P
Site 18
S138
A
K
A
L
S
G
T
S
P
D
D
V
Q
P
G
Site 19
S147
D
D
V
Q
P
G
P
S
V
G
P
P
S
K
D
Site 20
S152
G
P
S
V
G
P
P
S
K
D
K
D
K
V
L
Site 21
S161
D
K
D
K
V
L
P
S
F
W
I
P
S
L
T
Site 22
S166
L
P
S
F
W
I
P
S
L
T
P
E
A
K
A
Site 23
T168
S
F
W
I
P
S
L
T
P
E
A
K
A
T
K
Site 24
T174
L
T
P
E
A
K
A
T
K
L
E
K
P
S
R
Site 25
T184
E
K
P
S
R
T
V
T
C
P
M
S
G
K
P
Site 26
S188
R
T
V
T
C
P
M
S
G
K
P
L
R
M
S
Site 27
S195
S
G
K
P
L
R
M
S
D
L
T
P
V
H
F
Site 28
T203
D
L
T
P
V
H
F
T
P
L
D
S
S
V
D
Site 29
T216
V
D
R
V
G
L
I
T
R
S
E
R
Y
V
C
Site 30
Y221
L
I
T
R
S
E
R
Y
V
C
A
V
T
R
D
Site 31
T234
R
D
S
L
S
N
A
T
P
C
A
V
L
R
P
Site 32
T264
K
D
M
V
D
P
V
T
G
D
K
L
T
D
R
Site 33
S286
G
G
T
G
F
A
G
S
G
V
K
L
Q
A
E
Site 34
S295
V
K
L
Q
A
E
K
S
R
P
V
M
Q
A
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation