KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
NOP58
Full Name:
Nucleolar protein 58
Alias:
HSPC120; NOL5; NOP5; NOP5/NOP58; NOP58 ribonucleoprotein; Nucleolar protein 5; Nucleolar protein 58: Nucleolar protein 5; Nucleolar protein NOP5; Nucleolar protein NOP5/NOP58
Type:
RNA binding protein
Mass (Da):
59578
Number AA:
529
UniProt ID:
Q9Y2X3
International Prot ID:
IPI00006379
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0031428
GO:0070761
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0030515
PhosphoSite+
KinaseNET
Biological Process:
GO:0016049
GO:0006364
GO:0006608
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y11
L
F
E
T
S
V
G
Y
A
I
F
K
V
L
N
Site 2
S27
K
K
L
Q
E
V
D
S
L
W
K
E
F
E
T
Site 3
T34
S
L
W
K
E
F
E
T
P
E
K
A
N
K
I
Site 4
S109
L
N
L
S
C
I
H
S
P
V
V
N
E
L
M
Site 5
S121
E
L
M
R
G
I
R
S
Q
M
D
G
L
I
P
Site 6
S145
M
C
L
G
L
A
H
S
L
S
R
Y
R
L
K
Site 7
S147
L
G
L
A
H
S
L
S
R
Y
R
L
K
F
S
Site 8
Y149
L
A
H
S
L
S
R
Y
R
L
K
F
S
A
D
Site 9
Y179
L
D
K
E
L
N
N
Y
I
M
R
C
R
E
W
Site 10
S199
P
E
L
G
K
I
I
S
D
N
L
T
Y
C
K
Site 11
T203
K
I
I
S
D
N
L
T
Y
C
K
C
L
Q
K
Site 12
Y217
K
V
G
D
R
K
N
Y
A
S
A
K
L
S
E
Site 13
S219
G
D
R
K
N
Y
A
S
A
K
L
S
E
L
L
Site 14
S223
N
Y
A
S
A
K
L
S
E
L
L
P
E
E
V
Site 15
S247
I
S
M
G
T
E
V
S
E
E
D
I
C
N
I
Site 16
Y267
Q
V
I
E
I
S
E
Y
R
T
Q
L
Y
E
Y
Site 17
T269
I
E
I
S
E
Y
R
T
Q
L
Y
E
Y
L
Q
Site 18
Y272
S
E
Y
R
T
Q
L
Y
E
Y
L
Q
N
R
M
Site 19
Y274
Y
R
T
Q
L
Y
E
Y
L
Q
N
R
M
M
A
Site 20
S304
R
L
I
A
H
A
G
S
L
L
N
L
A
K
H
Site 21
S331
A
L
F
R
A
L
K
S
R
R
D
T
P
K
Y
Site 22
T335
A
L
K
S
R
R
D
T
P
K
Y
G
L
I
Y
Site 23
Y338
S
R
R
D
T
P
K
Y
G
L
I
Y
H
A
S
Site 24
Y342
T
P
K
Y
G
L
I
Y
H
A
S
L
V
G
Q
Site 25
S351
A
S
L
V
G
Q
T
S
P
K
H
K
G
K
I
Site 26
Y372
K
T
V
L
A
I
R
Y
D
A
F
G
E
D
S
Site 27
S379
Y
D
A
F
G
E
D
S
S
S
A
M
G
V
E
Site 28
S381
A
F
G
E
D
S
S
S
A
M
G
V
E
N
R
Site 29
T397
K
L
E
A
R
L
R
T
L
E
D
R
G
I
R
Site 30
S407
D
R
G
I
R
K
I
S
G
T
G
K
A
L
A
Site 31
T409
G
I
R
K
I
S
G
T
G
K
A
L
A
K
T
Site 32
T416
T
G
K
A
L
A
K
T
E
K
Y
E
H
K
S
Site 33
Y419
A
L
A
K
T
E
K
Y
E
H
K
S
E
V
K
Site 34
S423
T
E
K
Y
E
H
K
S
E
V
K
T
Y
D
P
Site 35
T427
E
H
K
S
E
V
K
T
Y
D
P
S
G
D
S
Site 36
Y428
H
K
S
E
V
K
T
Y
D
P
S
G
D
S
T
Site 37
S431
E
V
K
T
Y
D
P
S
G
D
S
T
L
P
T
Site 38
S434
T
Y
D
P
S
G
D
S
T
L
P
T
C
S
K
Site 39
T435
Y
D
P
S
G
D
S
T
L
P
T
C
S
K
K
Site 40
T438
S
G
D
S
T
L
P
T
C
S
K
K
R
K
I
Site 41
S440
D
S
T
L
P
T
C
S
K
K
R
K
I
E
Q
Site 42
T455
V
D
K
E
D
E
I
T
E
K
K
A
K
K
A
Site 43
T482
K
V
A
E
E
E
E
T
S
V
K
K
K
K
K
Site 44
S483
V
A
E
E
E
E
T
S
V
K
K
K
K
K
R
Site 45
S502
H
I
K
E
E
P
L
S
E
E
E
P
C
T
S
Site 46
T508
L
S
E
E
E
P
C
T
S
T
A
I
A
S
P
Site 47
S509
S
E
E
E
P
C
T
S
T
A
I
A
S
P
E
Site 48
T510
E
E
E
P
C
T
S
T
A
I
A
S
P
E
K
Site 49
S514
C
T
S
T
A
I
A
S
P
E
K
K
K
K
K
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation