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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TBC1D30
Full Name:
Alias:
Type:
Mass (Da):
102743
Number AA:
924
UniProt ID:
Q9Y2I9
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T15
G
G
R
P
G
L
R
T
E
L
E
F
R
G
G
Site 2
S30
G
G
E
A
R
L
E
S
Q
E
E
E
T
I
P
Site 3
S55
A
A
E
R
P
R
R
S
R
D
T
W
D
G
D
Site 4
T58
R
P
R
R
S
R
D
T
W
D
G
D
E
D
T
Site 5
T65
T
W
D
G
D
E
D
T
E
P
G
E
A
C
G
Site 6
S76
E
A
C
G
G
R
T
S
R
T
A
S
L
V
S
Site 7
T78
C
G
G
R
T
S
R
T
A
S
L
V
S
G
L
Site 8
S80
G
R
T
S
R
T
A
S
L
V
S
G
L
L
N
Site 9
Y90
S
G
L
L
N
E
L
Y
S
C
T
E
E
E
E
Site 10
S91
G
L
L
N
E
L
Y
S
C
T
E
E
E
E
A
Site 11
S114
G
R
R
R
R
R
D
S
L
D
S
S
T
E
A
Site 12
S117
R
R
R
D
S
L
D
S
S
T
E
A
S
G
S
Site 13
S118
R
R
D
S
L
D
S
S
T
E
A
S
G
S
D
Site 14
T119
R
D
S
L
D
S
S
T
E
A
S
G
S
D
V
Site 15
S122
L
D
S
S
T
E
A
S
G
S
D
V
V
L
G
Site 16
S124
S
S
T
E
A
S
G
S
D
V
V
L
G
G
R
Site 17
S137
G
R
S
G
A
G
D
S
R
V
L
Q
E
L
Q
Site 18
S148
Q
E
L
Q
E
R
P
S
Q
R
H
Q
M
L
Y
Site 19
Y155
S
Q
R
H
Q
M
L
Y
L
R
Q
K
D
A
N
Site 20
T166
K
D
A
N
E
L
K
T
I
L
R
E
L
K
Y
Site 21
Y173
T
I
L
R
E
L
K
Y
R
I
G
I
Q
S
A
Site 22
S179
K
Y
R
I
G
I
Q
S
A
K
L
L
R
H
L
Site 23
S211
T
A
C
L
Q
A
V
S
Q
K
R
R
V
D
T
Site 24
T218
S
Q
K
R
R
V
D
T
K
L
K
F
T
L
E
Site 25
T223
V
D
T
K
L
K
F
T
L
E
P
S
L
G
Q
Site 26
S227
L
K
F
T
L
E
P
S
L
G
Q
N
G
F
Q
Site 27
S247
L
K
A
V
A
R
L
S
T
G
I
P
K
E
W
Site 28
T248
K
A
V
A
R
L
S
T
G
I
P
K
E
W
R
Site 29
S286
R
F
T
F
N
E
R
S
N
P
D
D
D
S
M
Site 30
S292
R
S
N
P
D
D
D
S
M
G
I
Q
I
V
K
Site 31
T304
I
V
K
D
L
H
R
T
G
C
S
S
Y
C
G
Site 32
S308
L
H
R
T
G
C
S
S
Y
C
G
Q
E
A
E
Site 33
Y328
L
K
R
V
L
L
A
Y
A
R
W
N
K
T
V
Site 34
Y337
R
W
N
K
T
V
G
Y
C
Q
G
F
N
I
L
Site 35
S374
I
D
K
V
L
P
E
S
Y
F
V
N
N
L
R
Site 36
S402
R
M
K
L
P
E
L
S
Q
H
L
D
T
L
Q
Site 37
T407
E
L
S
Q
H
L
D
T
L
Q
R
T
A
N
K
Site 38
Y420
N
K
E
S
G
G
G
Y
E
P
P
L
T
N
V
Site 39
T425
G
G
Y
E
P
P
L
T
N
V
F
T
M
Q
W
Site 40
T435
F
T
M
Q
W
F
L
T
L
F
A
T
C
L
P
Site 41
T481
E
Q
I
E
C
C
E
T
A
D
E
F
Y
S
T
Site 42
Y486
C
E
T
A
D
E
F
Y
S
T
M
G
R
L
T
Site 43
T488
T
A
D
E
F
Y
S
T
M
G
R
L
T
Q
E
Site 44
T493
Y
S
T
M
G
R
L
T
Q
E
M
L
E
N
D
Site 45
T510
Q
S
H
E
L
M
Q
T
V
Y
S
M
A
P
F
Site 46
Y529
L
A
E
L
R
E
K
Y
T
Y
N
I
T
P
F
Site 47
Y531
E
L
R
E
K
Y
T
Y
N
I
T
P
F
P
A
Site 48
T534
E
K
Y
T
Y
N
I
T
P
F
P
A
T
V
K
Site 49
T539
N
I
T
P
F
P
A
T
V
K
P
T
S
V
S
Site 50
S544
P
A
T
V
K
P
T
S
V
S
G
R
H
S
K
Site 51
S546
T
V
K
P
T
S
V
S
G
R
H
S
K
A
R
Site 52
S550
T
S
V
S
G
R
H
S
K
A
R
D
S
D
E
Site 53
S555
R
H
S
K
A
R
D
S
D
E
E
N
D
P
D
Site 54
Y588
L
A
P
E
L
Q
K
Y
Q
K
Q
I
K
E
P
Site 55
S600
K
E
P
N
E
E
Q
S
L
R
S
N
N
I
A
Site 56
S610
S
N
N
I
A
E
L
S
P
G
A
I
N
S
C
Site 57
S616
L
S
P
G
A
I
N
S
C
R
S
E
Y
H
A
Site 58
Y621
I
N
S
C
R
S
E
Y
H
A
A
F
N
S
M
Site 59
T635
M
M
M
E
R
M
T
T
D
I
N
A
L
K
R
Site 60
Y644
I
N
A
L
K
R
Q
Y
S
R
I
K
K
K
Q
Site 61
S645
N
A
L
K
R
Q
Y
S
R
I
K
K
K
Q
Q
Site 62
Y659
Q
Q
Q
V
H
Q
V
Y
I
R
A
D
K
G
P
Site 63
T668
R
A
D
K
G
P
V
T
S
I
L
P
S
Q
V
Site 64
S669
A
D
K
G
P
V
T
S
I
L
P
S
Q
V
N
Site 65
T693
L
G
K
K
M
K
M
T
N
R
A
A
K
N
A
Site 66
T708
V
I
H
I
P
G
H
T
G
G
K
I
S
P
V
Site 67
S713
G
H
T
G
G
K
I
S
P
V
P
Y
E
D
L
Site 68
Y717
G
K
I
S
P
V
P
Y
E
D
L
K
T
K
L
Site 69
T722
V
P
Y
E
D
L
K
T
K
L
N
S
P
W
R
Site 70
S726
D
L
K
T
K
L
N
S
P
W
R
T
H
I
R
Site 71
T730
K
L
N
S
P
W
R
T
H
I
R
V
H
K
K
Site 72
T742
H
K
K
N
M
P
R
T
K
S
H
P
G
C
G
Site 73
S744
K
N
M
P
R
T
K
S
H
P
G
C
G
D
T
Site 74
T751
S
H
P
G
C
G
D
T
V
G
L
I
D
E
Q
Site 75
S762
I
D
E
Q
N
E
A
S
K
T
N
G
L
G
A
Site 76
T764
E
Q
N
E
A
S
K
T
N
G
L
G
A
A
E
Site 77
S786
A
T
A
G
R
E
G
S
S
P
E
G
S
T
R
Site 78
S787
T
A
G
R
E
G
S
S
P
E
G
S
T
R
R
Site 79
S791
E
G
S
S
P
E
G
S
T
R
R
T
I
E
G
Site 80
T795
P
E
G
S
T
R
R
T
I
E
G
Q
S
P
E
Site 81
S800
R
R
T
I
E
G
Q
S
P
E
P
V
F
G
D
Site 82
S850
R
H
C
P
E
P
P
S
A
P
E
E
N
K
A
Site 83
S859
P
E
E
N
K
A
T
S
K
A
P
Q
G
S
N
Site 84
S865
T
S
K
A
P
Q
G
S
N
S
K
T
P
I
F
Site 85
S867
K
A
P
Q
G
S
N
S
K
T
P
I
F
S
P
Site 86
T869
P
Q
G
S
N
S
K
T
P
I
F
S
P
F
P
Site 87
S873
N
S
K
T
P
I
F
S
P
F
P
S
V
K
P
Site 88
S877
P
I
F
S
P
F
P
S
V
K
P
L
R
K
S
Site 89
S884
S
V
K
P
L
R
K
S
A
T
A
R
N
L
G
Site 90
T886
K
P
L
R
K
S
A
T
A
R
N
L
G
L
Y
Site 91
Y893
T
A
R
N
L
G
L
Y
G
P
T
E
R
T
P
Site 92
T899
L
Y
G
P
T
E
R
T
P
T
V
H
F
P
Q
Site 93
T901
G
P
T
E
R
T
P
T
V
H
F
P
Q
M
S
Site 94
S908
T
V
H
F
P
Q
M
S
R
S
F
S
K
P
G
Site 95
S910
H
F
P
Q
M
S
R
S
F
S
K
P
G
G
G
Site 96
S912
P
Q
M
S
R
S
F
S
K
P
G
G
G
N
S
Site 97
S919
S
K
P
G
G
G
N
S
G
T
K
K
R
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation