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Updated November 2019
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Protein Info
Short Name:
FNDC3A
Full Name:
Fibronectin type-III domain-containing protein 3A
Alias:
BA203I16.5; Fibronectin type III domain containing 3A; Fibronectin type-III domain-containing protein 3a; FND3A; FNDC3; KIAA0970; Putative DKFZp686I166
Type:
Unknown function
Mass (Da):
131852
Number AA:
1198
UniProt ID:
Q9Y2H6
International Prot ID:
IPI00456630
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005794
GO:0016021
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T10
E
H
P
P
L
L
D
T
T
Q
I
L
S
S
D
Site 2
T11
H
P
P
L
L
D
T
T
Q
I
L
S
S
D
I
Site 3
T46
V
N
P
G
E
A
F
T
I
R
R
E
D
G
Q
Site 4
S67
P
A
Q
V
P
M
M
S
P
N
G
S
V
P
P
Site 5
S71
P
M
M
S
P
N
G
S
V
P
P
I
Y
V
P
Site 6
Y76
N
G
S
V
P
P
I
Y
V
P
P
G
Y
A
P
Site 7
Y81
P
I
Y
V
P
P
G
Y
A
P
Q
V
I
E
D
Site 8
S107
A
P
E
F
H
P
G
S
H
T
V
L
H
R
S
Site 9
T109
E
F
H
P
G
S
H
T
V
L
H
R
S
P
H
Site 10
S114
S
H
T
V
L
H
R
S
P
H
P
P
L
P
G
Site 11
T127
P
G
F
I
P
V
P
T
M
M
P
P
P
P
R
Site 12
Y137
P
P
P
P
R
H
M
Y
S
P
V
T
G
A
G
Site 13
S138
P
P
P
R
H
M
Y
S
P
V
T
G
A
G
D
Site 14
Y150
A
G
D
M
T
T
Q
Y
M
P
Q
Y
Q
S
S
Site 15
Y154
T
T
Q
Y
M
P
Q
Y
Q
S
S
Q
V
Y
G
Site 16
Y160
Q
Y
Q
S
S
Q
V
Y
G
D
V
D
A
H
S
Site 17
S167
Y
G
D
V
D
A
H
S
T
H
G
R
S
N
F
Site 18
T168
G
D
V
D
A
H
S
T
H
G
R
S
N
F
R
Site 19
S179
S
N
F
R
D
E
R
S
S
K
T
Y
E
R
L
Site 20
S180
N
F
R
D
E
R
S
S
K
T
Y
E
R
L
Q
Site 21
T182
R
D
E
R
S
S
K
T
Y
E
R
L
Q
K
K
Site 22
Y183
D
E
R
S
S
K
T
Y
E
R
L
Q
K
K
L
Site 23
T196
K
L
K
D
R
Q
G
T
Q
K
D
K
M
S
S
Site 24
S202
G
T
Q
K
D
K
M
S
S
P
P
S
S
P
Q
Site 25
S203
T
Q
K
D
K
M
S
S
P
P
S
S
P
Q
K
Site 26
S206
D
K
M
S
S
P
P
S
S
P
Q
K
C
P
S
Site 27
S207
K
M
S
S
P
P
S
S
P
Q
K
C
P
S
P
Site 28
S213
S
S
P
Q
K
C
P
S
P
I
N
E
H
N
G
Site 29
S234
A
G
G
I
N
T
G
S
A
K
I
K
S
G
K
Site 30
S239
T
G
S
A
K
I
K
S
G
K
G
K
G
G
T
Site 31
T250
K
G
G
T
Q
V
D
T
E
I
E
E
K
D
E
Site 32
T259
I
E
E
K
D
E
E
T
K
A
F
E
A
L
L
Site 33
T285
Q
A
R
T
V
V
L
T
W
S
P
P
S
S
L
Site 34
S291
L
T
W
S
P
P
S
S
L
I
N
G
E
T
D
Site 35
T297
S
S
L
I
N
G
E
T
D
E
S
S
V
P
E
Site 36
S300
I
N
G
E
T
D
E
S
S
V
P
E
L
Y
G
Site 37
S301
N
G
E
T
D
E
S
S
V
P
E
L
Y
G
Y
Site 38
S313
Y
G
Y
E
V
L
I
S
S
T
G
K
D
G
K
Site 39
S314
G
Y
E
V
L
I
S
S
T
G
K
D
G
K
Y
Site 40
Y321
S
T
G
K
D
G
K
Y
K
S
V
Y
V
G
E
Site 41
S323
G
K
D
G
K
Y
K
S
V
Y
V
G
E
E
T
Site 42
Y325
D
G
K
Y
K
S
V
Y
V
G
E
E
T
N
I
Site 43
T333
V
G
E
E
T
N
I
T
L
N
D
L
K
P
A
Site 44
Y343
D
L
K
P
A
M
D
Y
H
A
K
V
Q
A
E
Site 45
Y351
H
A
K
V
Q
A
E
Y
N
S
I
K
G
T
P
Site 46
S353
K
V
Q
A
E
Y
N
S
I
K
G
T
P
S
E
Site 47
T357
E
Y
N
S
I
K
G
T
P
S
E
A
E
I
F
Site 48
T366
S
E
A
E
I
F
T
T
L
S
C
E
P
D
I
Site 49
S368
A
E
I
F
T
T
L
S
C
E
P
D
I
P
N
Site 50
T383
P
P
R
I
A
N
R
T
K
N
S
L
T
L
Q
Site 51
S386
I
A
N
R
T
K
N
S
L
T
L
Q
W
K
A
Site 52
T388
N
R
T
K
N
S
L
T
L
Q
W
K
A
P
S
Site 53
S395
T
L
Q
W
K
A
P
S
D
N
G
S
K
I
Q
Site 54
S399
K
A
P
S
D
N
G
S
K
I
Q
N
F
V
L
Site 55
S444
M
G
C
K
F
R
L
S
A
R
N
D
Y
G
T
Site 56
Y449
R
L
S
A
R
N
D
Y
G
T
S
G
F
S
E
Site 57
T451
S
A
R
N
D
Y
G
T
S
G
F
S
E
E
V
Site 58
S455
D
Y
G
T
S
G
F
S
E
E
V
L
Y
Y
T
Site 59
Y460
G
F
S
E
E
V
L
Y
Y
T
S
G
C
A
P
Site 60
Y461
F
S
E
E
V
L
Y
Y
T
S
G
C
A
P
S
Site 61
S484
K
A
G
I
T
W
L
S
L
Q
W
S
K
P
S
Site 62
S488
T
W
L
S
L
Q
W
S
K
P
S
G
T
P
S
Site 63
S491
S
L
Q
W
S
K
P
S
G
T
P
S
D
E
G
Site 64
T493
Q
W
S
K
P
S
G
T
P
S
D
E
G
I
S
Site 65
S495
S
K
P
S
G
T
P
S
D
E
G
I
S
Y
I
Site 66
Y501
P
S
D
E
G
I
S
Y
I
L
E
M
E
E
E
Site 67
Y512
M
E
E
E
T
S
G
Y
G
F
K
P
K
Y
D
Site 68
Y518
G
Y
G
F
K
P
K
Y
D
G
E
D
L
A
Y
Site 69
Y525
Y
D
G
E
D
L
A
Y
T
V
K
N
L
R
R
Site 70
T526
D
G
E
D
L
A
Y
T
V
K
N
L
R
R
S
Site 71
S533
T
V
K
N
L
R
R
S
T
K
Y
K
F
K
V
Site 72
T534
V
K
N
L
R
R
S
T
K
Y
K
F
K
V
I
Site 73
Y536
N
L
R
R
S
T
K
Y
K
F
K
V
I
A
Y
Site 74
Y543
Y
K
F
K
V
I
A
Y
N
S
E
G
K
S
N
Site 75
S545
F
K
V
I
A
Y
N
S
E
G
K
S
N
P
S
Site 76
S549
A
Y
N
S
E
G
K
S
N
P
S
E
V
V
E
Site 77
T558
P
S
E
V
V
E
F
T
T
C
P
D
K
P
G
Site 78
S571
P
G
I
P
V
K
P
S
V
K
G
K
I
H
S
Site 79
S578
S
V
K
G
K
I
H
S
H
S
F
K
I
T
W
Site 80
S580
K
G
K
I
H
S
H
S
F
K
I
T
W
D
P
Site 81
T584
H
S
H
S
F
K
I
T
W
D
P
P
K
D
N
Site 82
Y639
C
F
Y
R
L
R
V
Y
C
I
S
D
G
G
Q
Site 83
S642
R
L
R
V
Y
C
I
S
D
G
G
Q
S
A
V
Site 84
T657
S
E
S
L
L
V
Q
T
P
A
V
P
P
G
P
Site 85
S695
V
D
G
G
S
P
I
S
C
Y
S
V
E
M
S
Site 86
S698
G
S
P
I
S
C
Y
S
V
E
M
S
P
I
E
Site 87
S702
S
C
Y
S
V
E
M
S
P
I
E
K
D
E
P
Site 88
Y713
K
D
E
P
R
E
V
Y
Q
G
S
E
V
E
C
Site 89
T721
Q
G
S
E
V
E
C
T
V
S
S
L
L
P
G
Site 90
S723
S
E
V
E
C
T
V
S
S
L
L
P
G
K
T
Site 91
T730
S
S
L
L
P
G
K
T
Y
S
F
R
L
R
A
Site 92
S732
L
L
P
G
K
T
Y
S
F
R
L
R
A
A
N
Site 93
S747
K
M
G
F
G
P
F
S
E
K
C
D
I
T
T
Site 94
T753
F
S
E
K
C
D
I
T
T
A
P
G
P
P
D
Site 95
T754
S
E
K
C
D
I
T
T
A
P
G
P
P
D
Q
Site 96
S784
V
N
W
E
V
P
L
S
N
G
T
D
V
T
E
Site 97
T790
L
S
N
G
T
D
V
T
E
Y
R
L
E
W
G
Site 98
Y792
N
G
T
D
V
T
E
Y
R
L
E
W
G
G
V
Site 99
Y807
E
G
S
M
Q
I
C
Y
C
G
P
G
L
S
Y
Site 100
Y814
Y
C
G
P
G
L
S
Y
E
I
K
G
L
S
P
Site 101
S820
S
Y
E
I
K
G
L
S
P
A
T
T
Y
Y
C
Site 102
T824
K
G
L
S
P
A
T
T
Y
Y
C
R
V
Q
A
Site 103
Y872
D
E
I
E
N
P
H
Y
S
P
S
T
C
L
A
Site 104
S873
E
I
E
N
P
H
Y
S
P
S
T
C
L
A
I
Site 105
S890
E
K
P
C
D
H
G
S
E
I
L
A
Y
S
I
Site 106
Y895
H
G
S
E
I
L
A
Y
S
I
D
F
G
D
K
Site 107
S904
I
D
F
G
D
K
Q
S
L
T
V
G
K
V
T
Site 108
T906
F
G
D
K
Q
S
L
T
V
G
K
V
T
S
Y
Site 109
T922
I
N
N
L
Q
P
D
T
T
Y
R
I
R
I
Q
Site 110
T923
N
N
L
Q
P
D
T
T
Y
R
I
R
I
Q
A
Site 111
Y924
N
L
Q
P
D
T
T
Y
R
I
R
I
Q
A
L
Site 112
S933
I
R
I
Q
A
L
N
S
L
G
A
G
P
F
S
Site 113
S940
S
L
G
A
G
P
F
S
H
M
I
K
L
K
T
Site 114
T947
S
H
M
I
K
L
K
T
K
P
L
P
P
D
P
Site 115
T975
K
L
K
W
G
E
G
T
P
K
T
L
S
T
D
Site 116
T978
W
G
E
G
T
P
K
T
L
S
T
D
S
I
Q
Site 117
S980
E
G
T
P
K
T
L
S
T
D
S
I
Q
Y
H
Site 118
T981
G
T
P
K
T
L
S
T
D
S
I
Q
Y
H
L
Site 119
S983
P
K
T
L
S
T
D
S
I
Q
Y
H
L
Q
M
Site 120
S999
D
K
N
G
R
F
V
S
L
Y
R
G
P
C
H
Site 121
Y1001
N
G
R
F
V
S
L
Y
R
G
P
C
H
T
Y
Site 122
T1007
L
Y
R
G
P
C
H
T
Y
K
V
Q
R
L
N
Site 123
T1017
V
Q
R
L
N
E
S
T
S
Y
K
F
C
I
Q
Site 124
S1018
Q
R
L
N
E
S
T
S
Y
K
F
C
I
Q
A
Site 125
Y1019
R
L
N
E
S
T
S
Y
K
F
C
I
Q
A
C
Site 126
S1035
E
A
G
E
G
P
L
S
Q
E
Y
I
F
T
T
Site 127
Y1038
E
G
P
L
S
Q
E
Y
I
F
T
T
P
K
S
Site 128
T1041
L
S
Q
E
Y
I
F
T
T
P
K
S
V
P
A
Site 129
T1042
S
Q
E
Y
I
F
T
T
P
K
S
V
P
A
A
Site 130
Y1096
D
S
E
F
K
Q
I
Y
K
G
P
D
S
S
F
Site 131
S1101
Q
I
Y
K
G
P
D
S
S
F
R
Y
S
S
L
Site 132
S1102
I
Y
K
G
P
D
S
S
F
R
Y
S
S
L
Q
Site 133
Y1105
G
P
D
S
S
F
R
Y
S
S
L
Q
L
N
C
Site 134
S1106
P
D
S
S
F
R
Y
S
S
L
Q
L
N
C
E
Site 135
S1107
D
S
S
F
R
Y
S
S
L
Q
L
N
C
E
Y
Site 136
S1127
A
I
R
Q
C
Q
D
S
L
G
H
Q
D
L
V
Site 137
S1145
S
T
T
V
L
F
I
S
Q
R
T
E
P
P
A
Site 138
S1153
Q
R
T
E
P
P
A
S
T
N
R
D
T
V
E
Site 139
T1158
P
A
S
T
N
R
D
T
V
E
S
T
R
T
R
Site 140
S1161
T
N
R
D
T
V
E
S
T
R
T
R
R
A
L
Site 141
T1164
D
T
V
E
S
T
R
T
R
R
A
L
S
D
E
Site 142
S1169
T
R
T
R
R
A
L
S
D
E
Q
C
A
A
V
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation