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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MTMR6
Full Name:
Myotubularin-related protein 6
Alias:
MTR6;EC 3.1.3.
Type:
Phosphatase, lipid, sugars, aminosugars
Mass (Da):
71954
Number AA:
621
UniProt ID:
Q9Y217
International Prot ID:
IPI00329385
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005635
GO:0005737
Uniprot
OncoNet
Molecular Function:
GO:0015269
GO:0004722
GO:0004725
PhosphoSite+
KinaseNET
Biological Process:
GO:0006470
GO:0006470
GO:0006793
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
E
H
I
R
T
T
K
V
E
Q
V
K
L
Site 2
S19
V
K
L
L
D
R
F
S
T
S
N
K
S
L
T
Site 3
T20
K
L
L
D
R
F
S
T
S
N
K
S
L
T
G
Site 4
S21
L
L
D
R
F
S
T
S
N
K
S
L
T
G
T
Site 5
S24
R
F
S
T
S
N
K
S
L
T
G
T
L
Y
L
Site 6
T28
S
N
K
S
L
T
G
T
L
Y
L
T
A
T
H
Site 7
Y92
E
R
D
C
H
D
I
Y
N
S
L
L
Q
L
S
Site 8
Y104
Q
L
S
K
Q
A
K
Y
E
D
L
Y
A
F
S
Site 9
Y108
Q
A
K
Y
E
D
L
Y
A
F
S
Y
N
P
K
Site 10
Y134
L
I
D
L
A
E
E
Y
K
R
M
G
V
P
N
Site 11
S142
K
R
M
G
V
P
N
S
H
W
Q
L
S
D
A
Site 12
S147
P
N
S
H
W
Q
L
S
D
A
N
R
D
Y
K
Site 13
Y153
L
S
D
A
N
R
D
Y
K
I
C
E
T
Y
P
Site 14
T158
R
D
Y
K
I
C
E
T
Y
P
R
E
L
Y
V
Site 15
Y159
D
Y
K
I
C
E
T
Y
P
R
E
L
Y
V
P
Site 16
Y164
E
T
Y
P
R
E
L
Y
V
P
R
I
A
S
K
Site 17
S177
S
K
P
I
I
V
G
S
S
K
F
R
S
K
G
Site 18
S178
K
P
I
I
V
G
S
S
K
F
R
S
K
G
R
Site 19
S182
V
G
S
S
K
F
R
S
K
G
R
F
P
V
L
Site 20
S190
K
G
R
F
P
V
L
S
Y
Y
H
Q
D
K
E
Site 21
Y192
R
F
P
V
L
S
Y
Y
H
Q
D
K
E
A
A
Site 22
S208
C
R
C
S
Q
P
L
S
G
F
S
A
R
C
L
Site 23
S211
S
Q
P
L
S
G
F
S
A
R
C
L
E
D
E
Site 24
S225
E
H
L
L
Q
A
I
S
K
A
N
P
V
N
R
Site 25
Y235
N
P
V
N
R
Y
M
Y
V
M
D
T
R
P
K
Site 26
Y255
N
R
A
A
G
K
G
Y
E
N
E
D
N
Y
S
Site 27
Y261
G
Y
E
N
E
D
N
Y
S
N
I
R
F
Q
F
Site 28
T290
K
L
L
E
V
N
G
T
K
G
L
S
V
N
D
Site 29
S294
V
N
G
T
K
G
L
S
V
N
D
F
Y
S
G
Site 30
Y299
G
L
S
V
N
D
F
Y
S
G
L
E
S
S
G
Site 31
S300
L
S
V
N
D
F
Y
S
G
L
E
S
S
G
W
Site 32
S304
D
F
Y
S
G
L
E
S
S
G
W
L
R
H
I
Site 33
S305
F
Y
S
G
L
E
S
S
G
W
L
R
H
I
K
Site 34
S344
S
D
G
W
D
R
T
S
Q
V
C
S
L
G
S
Site 35
S356
L
G
S
L
L
L
D
S
Y
Y
R
T
I
K
G
Site 36
Y357
G
S
L
L
L
D
S
Y
Y
R
T
I
K
G
F
Site 37
S374
L
I
E
K
D
W
I
S
F
G
H
K
F
S
E
Site 38
S380
I
S
F
G
H
K
F
S
E
R
C
G
Q
L
D
Site 39
S394
D
G
D
P
K
E
V
S
P
V
F
T
Q
F
L
Site 40
T454
E
L
K
L
K
E
K
T
Y
S
L
W
P
F
L
Site 41
S456
K
L
K
E
K
T
Y
S
L
W
P
F
L
L
E
Site 42
Y468
L
L
E
D
Q
K
K
Y
L
N
P
L
Y
S
S
Site 43
Y473
K
K
Y
L
N
P
L
Y
S
S
E
S
H
R
F
Site 44
S474
K
Y
L
N
P
L
Y
S
S
E
S
H
R
F
T
Site 45
S477
N
P
L
Y
S
S
E
S
H
R
F
T
V
L
E
Site 46
T481
S
S
E
S
H
R
F
T
V
L
E
P
N
T
V
Site 47
T505
M
Y
H
Q
F
D
R
T
L
H
P
R
Q
S
V
Site 48
S535
K
D
I
K
D
L
E
S
K
I
K
Q
R
K
N
Site 49
T545
K
Q
R
K
N
K
Q
T
D
G
I
L
T
K
E
Site 50
S556
L
T
K
E
L
L
H
S
V
H
P
E
S
P
N
Site 51
S561
L
H
S
V
H
P
E
S
P
N
L
K
T
S
L
Site 52
S567
E
S
P
N
L
K
T
S
L
C
F
K
E
Q
T
Site 53
T584
P
V
N
D
A
L
R
T
I
E
G
S
S
P
A
Site 54
S588
A
L
R
T
I
E
G
S
S
P
A
D
N
R
Y
Site 55
S589
L
R
T
I
E
G
S
S
P
A
D
N
R
Y
S
Site 56
Y595
S
S
P
A
D
N
R
Y
S
E
Y
A
E
E
F
Site 57
S596
S
P
A
D
N
R
Y
S
E
Y
A
E
E
F
S
Site 58
Y598
A
D
N
R
Y
S
E
Y
A
E
E
F
S
K
S
Site 59
S605
Y
A
E
E
F
S
K
S
E
P
A
V
V
S
L
Site 60
Y614
P
A
V
V
S
L
E
Y
G
V
A
R
M
T
C
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation