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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
DNM3
Full Name:
Dynamin-3
Alias:
Dynamin, testicular
Type:
Mass (Da):
97746
Number AA:
869
UniProt ID:
Q9UQ16
International Prot ID:
IPI00221332
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005856
GO:0005874
Uniprot
OncoNet
Molecular Function:
GO:0000166
GO:0003774
GO:0003824
PhosphoSite+
KinaseNET
Biological Process:
GO:0006810
GO:0006897
GO:0009987
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S21
N
R
L
Q
D
A
F
S
A
L
G
Q
S
C
L
Site 2
S45
G
G
Q
S
A
G
K
S
S
V
L
E
N
F
V
Site 3
S61
R
D
F
L
P
R
G
S
G
I
V
T
R
R
P
Site 4
T65
P
R
G
S
G
I
V
T
R
R
P
L
V
L
Q
Site 5
Y80
L
V
T
S
K
A
E
Y
A
E
F
L
H
C
K
Site 6
T109
E
A
E
T
D
R
V
T
G
M
N
K
G
I
S
Site 7
Y125
I
P
I
N
L
R
V
Y
S
P
H
V
L
N
L
Site 8
Y154
D
Q
P
P
D
I
E
Y
Q
I
R
E
M
I
M
Site 9
T214
L
D
L
M
D
E
G
T
D
A
R
D
V
L
E
Site 10
Y231
L
L
P
L
R
R
G
Y
V
G
V
V
N
R
S
Site 11
S238
Y
V
G
V
V
N
R
S
Q
K
D
I
D
G
K
Site 12
S261
A
E
R
K
F
F
L
S
H
P
A
Y
R
H
I
Site 13
Y265
F
F
L
S
H
P
A
Y
R
H
I
A
D
R
M
Site 14
T274
H
I
A
D
R
M
G
T
P
H
L
Q
K
V
L
Site 15
T286
K
V
L
N
Q
Q
L
T
N
H
I
R
D
T
L
Site 16
T292
L
T
N
H
I
R
D
T
L
P
N
F
R
N
K
Site 17
S306
K
L
Q
G
Q
L
L
S
I
E
H
E
V
E
A
Site 18
Y314
I
E
H
E
V
E
A
Y
K
N
F
K
P
E
D
Site 19
T326
P
E
D
P
T
R
K
T
K
A
L
L
Q
M
V
Site 20
S347
F
E
K
R
I
E
G
S
G
D
Q
V
D
T
L
Site 21
T353
G
S
G
D
Q
V
D
T
L
E
L
S
G
G
A
Site 22
S357
Q
V
D
T
L
E
L
S
G
G
A
K
I
N
R
Site 23
S389
K
E
L
R
R
E
I
S
Y
A
I
K
N
I
H
Site 24
Y390
E
L
R
R
E
I
S
Y
A
I
K
N
I
H
G
Site 25
T438
V
I
Q
E
L
I
N
T
V
K
K
C
T
K
K
Site 26
T456
F
P
R
L
C
E
E
T
E
R
I
V
A
N
H
Site 27
S504
A
N
A
Q
Q
R
S
S
Q
V
H
K
K
T
T
Site 28
T510
S
S
Q
V
H
K
K
T
T
V
G
N
Q
G
T
Site 29
T511
S
Q
V
H
K
K
T
T
V
G
N
Q
G
T
N
Site 30
S522
Q
G
T
N
L
P
P
S
R
Q
I
V
I
R
K
Site 31
T552
K
G
Y
W
F
V
L
T
A
E
S
L
S
W
Y
Site 32
Y559
T
A
E
S
L
S
W
Y
K
D
D
E
E
K
E
Site 33
Y569
D
E
E
K
E
K
K
Y
M
L
P
L
D
N
L
Site 34
S584
K
V
R
D
V
E
K
S
F
M
S
S
K
H
I
Site 35
Y603
N
T
E
Q
R
N
V
Y
K
D
Y
R
F
L
E
Site 36
Y606
Q
R
N
V
Y
K
D
Y
R
F
L
E
L
A
C
Site 37
S615
F
L
E
L
A
C
D
S
Q
E
D
V
D
S
W
Site 38
S621
D
S
Q
E
D
V
D
S
W
K
A
S
L
L
R
Site 39
S625
D
V
D
S
W
K
A
S
L
L
R
A
G
V
Y
Site 40
Y632
S
L
L
R
A
G
V
Y
P
D
K
S
V
A
E
Site 41
S636
A
G
V
Y
P
D
K
S
V
A
E
N
D
E
N
Site 42
S650
N
G
Q
A
E
N
F
S
M
D
P
Q
L
E
R
Site 43
S668
T
I
R
N
L
V
D
S
Y
M
S
I
I
N
K
Site 44
Y706
S
E
L
L
A
Q
L
Y
S
S
E
D
Q
N
T
Site 45
S707
E
L
L
A
Q
L
Y
S
S
E
D
Q
N
T
L
Site 46
T713
Y
S
S
E
D
Q
N
T
L
M
E
E
S
A
E
Site 47
Y732
R
D
E
M
L
R
M
Y
Q
A
L
K
E
A
L
Site 48
S761
A
P
P
P
V
D
D
S
W
I
Q
H
S
R
R
Site 49
S766
D
D
S
W
I
Q
H
S
R
R
S
P
P
P
S
Site 50
S769
W
I
Q
H
S
R
R
S
P
P
P
S
P
T
T
Site 51
S773
S
R
R
S
P
P
P
S
P
T
T
Q
R
R
P
Site 52
T775
R
S
P
P
P
S
P
T
T
Q
R
R
P
T
L
Site 53
T776
S
P
P
P
S
P
T
T
Q
R
R
P
T
L
S
Site 54
T781
P
T
T
Q
R
R
P
T
L
S
A
P
L
A
R
Site 55
S783
T
Q
R
R
P
T
L
S
A
P
L
A
R
P
T
Site 56
T790
S
A
P
L
A
R
P
T
S
G
R
G
P
A
P
Site 57
S791
A
P
L
A
R
P
T
S
G
R
G
P
A
P
A
Site 58
S801
G
P
A
P
A
I
P
S
P
G
P
H
S
G
A
Site 59
S806
I
P
S
P
G
P
H
S
G
A
P
P
V
P
F
Site 60
S823
G
P
L
P
P
F
P
S
S
S
D
S
F
G
A
Site 61
S824
P
L
P
P
F
P
S
S
S
D
S
F
G
A
P
Site 62
S825
L
P
P
F
P
S
S
S
D
S
F
G
A
P
P
Site 63
S827
P
F
P
S
S
S
D
S
F
G
A
P
P
Q
V
Site 64
T839
P
Q
V
P
S
R
P
T
R
A
P
P
S
V
P
Site 65
S844
R
P
T
R
A
P
P
S
V
P
S
R
R
P
P
Site 66
S847
R
A
P
P
S
V
P
S
R
R
P
P
P
S
P
Site 67
S853
P
S
R
R
P
P
P
S
P
T
R
P
T
I
I
Site 68
T858
P
P
S
P
T
R
P
T
I
I
R
P
L
E
S
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation