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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
Nna1
Full Name:
Cytosolic carboxypeptidase 1
Alias:
AGTPBP1; ATP/GTP binding protein 1; CBPC1; KIAA1035; Nervous system nuclear protein induced by axotomy
Type:
EC 3.4.17.-; Protease
Mass (Da):
138448
Number AA:
1220
UniProt ID:
Q9UPW5
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0004181
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0006508
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
L
K
V
I
P
E
K
S
L
T
N
N
S
R
I
Site 2
T13
V
I
P
E
K
S
L
T
N
N
S
R
I
V
G
Site 3
S35
I
N
A
E
P
S
E
S
D
T
A
R
Y
V
T
Site 4
T37
A
E
P
S
E
S
D
T
A
R
Y
V
T
S
K
Site 5
Y40
S
E
S
D
T
A
R
Y
V
T
S
K
I
L
H
Site 6
T42
S
D
T
A
R
Y
V
T
S
K
I
L
H
L
A
Site 7
S51
K
I
L
H
L
A
Q
S
Q
E
K
T
R
R
E
Site 8
T55
L
A
Q
S
Q
E
K
T
R
R
E
M
T
A
K
Site 9
T60
E
K
T
R
R
E
M
T
A
K
G
S
T
G
M
Site 10
S64
R
E
M
T
A
K
G
S
T
G
M
E
I
L
L
Site 11
T65
E
M
T
A
K
G
S
T
G
M
E
I
L
L
S
Site 12
S72
T
G
M
E
I
L
L
S
T
L
E
N
T
K
D
Site 13
T82
E
N
T
K
D
L
Q
T
T
L
N
I
L
S
I
Site 14
S103
A
G
G
G
R
R
V
S
F
L
V
T
K
G
G
Site 15
S122
L
Q
L
L
M
N
A
S
K
E
S
P
P
H
E
Site 16
S125
L
M
N
A
S
K
E
S
P
P
H
E
D
L
M
Site 17
S193
Y
S
A
N
S
V
N
S
V
S
L
G
K
N
G
Site 18
S213
F
K
I
I
G
P
F
S
K
K
N
S
S
L
I
Site 19
S217
G
P
F
S
K
K
N
S
S
L
I
K
V
A
L
Site 20
S218
P
F
S
K
K
N
S
S
L
I
K
V
A
L
D
Site 21
T235
A
A
L
L
K
S
K
T
N
A
R
R
A
V
D
Site 22
Y253
V
Q
V
L
L
T
I
Y
V
D
W
H
R
H
D
Site 23
S278
G
I
L
Q
S
L
K
S
V
T
N
I
K
L
G
Site 24
T280
L
Q
S
L
K
S
V
T
N
I
K
L
G
R
K
Site 25
Y299
A
N
G
M
K
I
L
Y
N
T
S
Q
E
C
L
Site 26
S302
M
K
I
L
Y
N
T
S
Q
E
C
L
A
V
R
Site 27
T335
K
N
R
L
P
L
P
T
I
K
S
S
F
H
F
Site 28
Y357
T
G
P
V
A
Q
L
Y
S
L
P
P
E
V
D
Site 29
S358
G
P
V
A
Q
L
Y
S
L
P
P
E
V
D
D
Site 30
S370
V
D
D
V
V
D
E
S
D
D
N
D
D
I
D
Site 31
T415
P
Q
Q
E
P
G
R
T
I
E
D
L
K
M
Y
Site 32
Y422
T
I
E
D
L
K
M
Y
E
H
L
F
P
E
L
Site 33
Y436
L
V
D
D
F
Q
D
Y
D
L
I
S
K
E
P
Site 34
S440
F
Q
D
Y
D
L
I
S
K
E
P
K
P
F
V
Site 35
T460
R
G
P
I
V
V
P
T
A
G
E
E
T
S
G
Site 36
S483
V
M
K
E
N
I
S
S
K
G
D
E
G
E
K
Site 37
S492
G
D
E
G
E
K
K
S
T
F
M
D
L
A
K
Site 38
T493
D
E
G
E
K
K
S
T
F
M
D
L
A
K
E
Site 39
T508
D
I
K
D
N
D
R
T
L
Q
Q
Q
P
G
D
Site 40
S521
G
D
Q
N
R
T
I
S
S
V
H
G
L
N
N
Site 41
S522
D
Q
N
R
T
I
S
S
V
H
G
L
N
N
D
Site 42
T538
V
K
A
L
D
R
I
T
L
Q
N
I
P
S
Q
Site 43
S544
I
T
L
Q
N
I
P
S
Q
T
A
P
G
F
T
Site 44
T605
E
T
E
D
D
E
D
T
E
S
N
S
S
V
E
Site 45
S607
E
D
D
E
D
T
E
S
N
S
S
V
E
Q
A
Site 46
S610
E
D
T
E
S
N
S
S
V
E
Q
A
S
V
E
Site 47
S615
N
S
S
V
E
Q
A
S
V
E
V
P
D
G
P
Site 48
Y630
T
L
H
D
P
D
L
Y
I
E
I
V
K
N
T
Site 49
S639
E
I
V
K
N
T
K
S
V
P
E
Y
S
E
V
Site 50
Y643
N
T
K
S
V
P
E
Y
S
E
V
A
Y
P
D
Site 51
S644
T
K
S
V
P
E
Y
S
E
V
A
Y
P
D
Y
Site 52
Y648
P
E
Y
S
E
V
A
Y
P
D
Y
F
G
H
I
Site 53
Y651
S
E
V
A
Y
P
D
Y
F
G
H
I
P
P
P
Site 54
Y668
E
P
I
L
E
R
P
Y
G
V
Q
R
T
K
I
Site 55
Y694
D
I
I
D
R
V
V
Y
D
L
D
N
P
N
Y
Site 56
Y701
Y
D
L
D
N
P
N
Y
T
I
P
E
E
G
D
Site 57
S714
G
D
I
L
K
F
N
S
K
F
E
S
G
N
L
Site 58
S718
K
F
N
S
K
F
E
S
G
N
L
R
K
V
I
Site 59
Y778
K
S
N
S
Q
F
N
Y
G
M
Q
P
L
M
Y
Site 60
Y785
Y
G
M
Q
P
L
M
Y
S
V
Q
E
A
L
N
Site 61
Y806
R
M
G
T
D
I
C
Y
Y
K
N
H
F
S
R
Site 62
Y807
M
G
T
D
I
C
Y
Y
K
N
H
F
S
R
S
Site 63
S812
C
Y
Y
K
N
H
F
S
R
S
S
V
A
A
G
Site 64
S814
Y
K
N
H
F
S
R
S
S
V
A
A
G
G
Q
Site 65
S815
K
N
H
F
S
R
S
S
V
A
A
G
G
Q
K
Site 66
S825
A
G
G
Q
K
G
K
S
Y
Y
T
I
T
F
T
Site 67
Y826
G
G
Q
K
G
K
S
Y
Y
T
I
T
F
T
V
Site 68
Y827
G
Q
K
G
K
S
Y
Y
T
I
T
F
T
V
N
Site 69
T830
G
K
S
Y
Y
T
I
T
F
T
V
N
F
P
H
Site 70
Y843
P
H
K
D
D
V
C
Y
F
A
Y
H
Y
P
Y
Site 71
Y850
Y
F
A
Y
H
Y
P
Y
T
Y
S
T
L
Q
M
Site 72
Y872
A
H
N
P
Q
Q
I
Y
F
R
K
D
V
L
C
Site 73
T881
R
K
D
V
L
C
E
T
L
S
G
N
S
C
P
Site 74
Y901
A
M
P
E
S
N
Y
Y
E
H
I
C
H
F
R
Site 75
Y912
C
H
F
R
N
R
P
Y
V
F
L
S
A
R
V
Site 76
S916
N
R
P
Y
V
F
L
S
A
R
V
H
P
G
E
Site 77
S927
H
P
G
E
T
N
A
S
W
V
M
K
G
T
L
Site 78
T933
A
S
W
V
M
K
G
T
L
E
Y
L
M
S
N
Site 79
S939
G
T
L
E
Y
L
M
S
N
N
P
T
A
Q
S
Site 80
T943
Y
L
M
S
N
N
P
T
A
Q
S
L
R
E
S
Site 81
S946
S
N
N
P
T
A
Q
S
L
R
E
S
Y
I
F
Site 82
S950
T
A
Q
S
L
R
E
S
Y
I
F
K
I
V
P
Site 83
S972
I
N
G
N
H
R
C
S
L
S
G
E
D
L
N
Site 84
S974
G
N
H
R
C
S
L
S
G
E
D
L
N
R
Q
Site 85
S984
D
L
N
R
Q
W
Q
S
P
S
P
D
L
H
P
Site 86
S986
N
R
Q
W
Q
S
P
S
P
D
L
H
P
T
I
Site 87
Y994
P
D
L
H
P
T
I
Y
H
A
K
G
L
L
Q
Site 88
Y1013
V
K
R
L
P
L
V
Y
C
D
Y
H
G
H
S
Site 89
Y1016
L
P
L
V
Y
C
D
Y
H
G
H
S
R
K
K
Site 90
Y1028
R
K
K
N
V
F
M
Y
G
C
S
I
K
E
T
Site 91
T1052
S
C
D
V
V
E
D
T
G
Y
R
T
L
P
K
Site 92
Y1054
D
V
V
E
D
T
G
Y
R
T
L
P
K
I
L
Site 93
T1056
V
E
D
T
G
Y
R
T
L
P
K
I
L
S
H
Site 94
S1080
C
S
F
V
V
E
K
S
K
E
S
T
A
R
V
Site 95
T1084
V
E
K
S
K
E
S
T
A
R
V
V
V
W
R
Site 96
S1098
R
E
I
G
V
Q
R
S
Y
T
M
E
S
T
L
Site 97
Y1099
E
I
G
V
Q
R
S
Y
T
M
E
S
T
L
C
Site 98
T1100
I
G
V
Q
R
S
Y
T
M
E
S
T
L
C
G
Site 99
T1104
R
S
Y
T
M
E
S
T
L
C
G
C
D
Q
G
Site 100
Y1113
C
G
C
D
Q
G
K
Y
K
G
L
Q
I
G
T
Site 101
T1141
L
L
R
L
K
R
L
T
S
P
L
E
Y
N
L
Site 102
S1142
L
R
L
K
R
L
T
S
P
L
E
Y
N
L
P
Site 103
Y1146
R
L
T
S
P
L
E
Y
N
L
P
S
S
L
L
Site 104
S1151
L
E
Y
N
L
P
S
S
L
L
D
F
E
N
D
Site 105
S1162
E
S
S
C
K
V
T
S
P
T
T
Y
V
L
D
Site 106
S1168
E
S
S
C
K
V
T
S
P
T
T
Y
V
L
D
Site 107
Y1172
K
V
T
S
P
T
T
Y
V
L
D
E
D
E
P
Site 108
Y1187
R
F
L
E
E
V
D
Y
S
A
E
S
N
D
E
Site 109
S1188
F
L
E
E
V
D
Y
S
A
E
S
N
D
E
L
Site 110
Y1206
L
A
E
N
V
G
D
Y
E
P
S
A
Q
E
E
Site 111
S1216
S
A
Q
E
E
V
L
S
D
S
E
L
S
R
T
Site 112
S1218
Q
E
E
V
L
S
D
S
E
L
S
R
T
Y
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation