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Updated November 2019
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Protein Info
Short Name:
CEP164
Full Name:
Centrosomal protein of 164 kDa
Alias:
CE164; centrosomal protein 164 kDa; centrosomal protein 164kDa; KIAA1052
Type:
Unknown function
Mass (Da):
164310
Number AA:
UniProt ID:
Q9UPV0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005814
GO:0005694
GO:0005829
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006281
GO:0051301
GO:0007067
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y18
Q
L
V
L
E
E
D
Y
D
E
T
Y
I
P
S
Site 2
T21
L
E
E
D
Y
D
E
T
Y
I
P
S
E
Q
E
Site 3
Y22
E
E
D
Y
D
E
T
Y
I
P
S
E
Q
E
I
Site 4
S25
Y
D
E
T
Y
I
P
S
E
Q
E
I
L
E
F
Site 5
Y73
Q
D
I
T
G
D
I
Y
Y
F
N
F
A
N
G
Site 6
Y74
D
I
T
G
D
I
Y
Y
F
N
F
A
N
G
Q
Site 7
Y92
D
H
P
C
D
E
H
Y
R
S
L
V
I
Q
E
Site 8
S94
P
C
D
E
H
Y
R
S
L
V
I
Q
E
R
A
Site 9
S104
I
Q
E
R
A
K
L
S
T
S
G
A
I
K
K
Site 10
S129
K
D
R
D
P
P
K
S
S
L
A
L
G
S
S
Site 11
S130
D
R
D
P
P
K
S
S
L
A
L
G
S
S
L
Site 12
T156
P
L
R
G
L
V
D
T
P
P
S
A
L
R
G
Site 13
S159
G
L
V
D
T
P
P
S
A
L
R
G
S
Q
S
Site 14
S164
P
P
S
A
L
R
G
S
Q
S
V
S
L
G
S
Site 15
S166
S
A
L
R
G
S
Q
S
V
S
L
G
S
S
V
Site 16
S168
L
R
G
S
Q
S
V
S
L
G
S
S
V
E
S
Site 17
S171
S
Q
S
V
S
L
G
S
S
V
E
S
G
R
Q
Site 18
S172
Q
S
V
S
L
G
S
S
V
E
S
G
R
Q
L
Site 19
S175
S
L
G
S
S
V
E
S
G
R
Q
L
G
E
L
Site 20
S186
L
G
E
L
M
L
P
S
Q
G
L
K
T
S
A
Site 21
S192
P
S
Q
G
L
K
T
S
A
Y
T
K
G
L
L
Site 22
Y194
Q
G
L
K
T
S
A
Y
T
K
G
L
L
G
S
Site 23
Y203
K
G
L
L
G
S
I
Y
E
D
K
T
A
L
S
Site 24
S210
Y
E
D
K
T
A
L
S
L
L
G
L
G
E
E
Site 25
S226
N
E
E
D
E
E
E
S
D
N
Q
S
V
H
S
Site 26
S230
E
E
E
S
D
N
Q
S
V
H
S
S
S
E
P
Site 27
S233
S
D
N
Q
S
V
H
S
S
S
E
P
L
R
N
Site 28
S234
D
N
Q
S
V
H
S
S
S
E
P
L
R
N
L
Site 29
S235
N
Q
S
V
H
S
S
S
E
P
L
R
N
L
H
Site 30
Y254
A
L
G
G
D
F
E
Y
E
E
S
L
R
T
S
Site 31
S257
G
D
F
E
Y
E
E
S
L
R
T
S
Q
P
E
Site 32
T260
E
Y
E
E
S
L
R
T
S
Q
P
E
E
K
K
Site 33
S261
Y
E
E
S
L
R
T
S
Q
P
E
E
K
K
D
Site 34
S270
P
E
E
K
K
D
V
S
L
D
S
D
A
A
G
Site 35
S273
K
K
D
V
S
L
D
S
D
A
A
G
P
P
T
Site 36
T280
S
D
A
A
G
P
P
T
P
C
K
P
S
S
P
Site 37
S285
P
P
T
P
C
K
P
S
S
P
G
A
D
S
S
Site 38
S286
P
T
P
C
K
P
S
S
P
G
A
D
S
S
L
Site 39
S291
P
S
S
P
G
A
D
S
S
L
S
S
A
V
G
Site 40
S292
S
S
P
G
A
D
S
S
L
S
S
A
V
G
K
Site 41
S294
P
G
A
D
S
S
L
S
S
A
V
G
K
G
R
Site 42
S295
G
A
D
S
S
L
S
S
A
V
G
K
G
R
Q
Site 43
S304
V
G
K
G
R
Q
G
S
G
A
R
P
G
L
P
Site 44
S319
E
K
E
E
N
E
K
S
E
P
K
I
C
R
N
Site 45
T329
K
I
C
R
N
L
V
T
P
K
A
D
P
T
G
Site 46
S337
P
K
A
D
P
T
G
S
E
P
A
K
A
S
E
Site 47
T351
E
K
E
A
P
E
D
T
V
D
A
G
E
E
G
Site 48
S359
V
D
A
G
E
E
G
S
R
R
E
E
A
A
K
Site 49
S373
K
E
P
K
K
K
A
S
A
L
E
E
G
S
S
Site 50
S379
A
S
A
L
E
E
G
S
S
D
A
S
Q
E
L
Site 51
S380
S
A
L
E
E
G
S
S
D
A
S
Q
E
L
E
Site 52
S383
E
E
G
S
S
D
A
S
Q
E
L
E
I
S
E
Site 53
S389
A
S
Q
E
L
E
I
S
E
H
M
K
E
P
Q
Site 54
S398
H
M
K
E
P
Q
L
S
D
S
I
A
S
D
P
Site 55
S400
K
E
P
Q
L
S
D
S
I
A
S
D
P
K
S
Site 56
S403
Q
L
S
D
S
I
A
S
D
P
K
S
F
H
G
Site 57
S407
S
I
A
S
D
P
K
S
F
H
G
L
D
F
G
Site 58
S420
F
G
F
R
S
R
I
S
E
H
L
L
D
V
D
Site 59
S452
G
I
E
D
K
D
D
S
Q
S
S
Q
D
E
L
Site 60
S454
E
D
K
D
D
S
Q
S
S
Q
D
E
L
Q
S
Site 61
S455
D
K
D
D
S
Q
S
S
Q
D
E
L
Q
S
K
Site 62
S461
S
S
Q
D
E
L
Q
S
K
Q
S
K
G
L
E
Site 63
S472
K
G
L
E
E
R
L
S
P
P
L
P
H
E
E
Site 64
S483
P
H
E
E
R
A
Q
S
P
P
R
S
L
A
T
Site 65
S487
R
A
Q
S
P
P
R
S
L
A
T
E
E
E
P
Site 66
S514
A
E
E
L
G
E
D
S
A
A
S
L
S
L
Q
Site 67
S519
E
D
S
A
A
S
L
S
L
Q
L
S
L
Q
R
Site 68
S523
A
S
L
S
L
Q
L
S
L
Q
R
E
Q
A
P
Site 69
S531
L
Q
R
E
Q
A
P
S
P
P
A
A
C
E
K
Site 70
S544
E
K
G
K
E
Q
H
S
Q
A
E
E
L
G
P
Site 71
S566
P
E
E
K
V
A
V
S
P
T
P
P
V
S
P
Site 72
T568
E
K
V
A
V
S
P
T
P
P
V
S
P
E
V
Site 73
S572
V
S
P
T
P
P
V
S
P
E
V
R
S
T
E
Site 74
S577
P
V
S
P
E
V
R
S
T
E
P
V
A
P
P
Site 75
T578
V
S
P
E
V
R
S
T
E
P
V
A
P
P
E
Site 76
S613
D
Q
R
H
L
L
E
S
K
Q
E
K
M
Q
Q
Site 77
S643
L
H
Q
Q
K
E
Q
S
L
S
S
L
R
E
R
Site 78
S645
Q
Q
K
E
Q
S
L
S
S
L
R
E
R
L
Q
Site 79
S646
Q
K
E
Q
S
L
S
S
L
R
E
R
L
Q
K
Site 80
S667
A
R
M
R
E
E
E
S
Q
R
L
S
W
L
R
Site 81
S671
E
E
E
S
Q
R
L
S
W
L
R
A
Q
V
Q
Site 82
S679
W
L
R
A
Q
V
Q
S
S
T
Q
A
D
E
D
Site 83
S695
I
R
A
E
Q
E
A
S
L
Q
K
L
R
E
E
Site 84
S705
K
L
R
E
E
L
E
S
Q
Q
K
A
E
R
A
Site 85
S713
Q
Q
K
A
E
R
A
S
L
E
Q
K
N
R
Q
Site 86
S732
L
K
E
E
I
E
A
S
E
K
S
E
Q
A
A
Site 87
T765
E
R
K
E
A
V
A
T
L
E
K
E
H
S
A
Site 88
S771
A
T
L
E
K
E
H
S
A
E
L
E
R
L
C
Site 89
S779
A
E
L
E
R
L
C
S
S
L
E
A
K
H
R
Site 90
S780
E
L
E
R
L
C
S
S
L
E
A
K
H
R
E
Site 91
S791
K
H
R
E
V
V
S
S
L
Q
K
K
I
Q
E
Site 92
Y828
K
S
Y
H
V
A
G
Y
E
H
E
L
S
S
L
Site 93
S833
A
G
Y
E
H
E
L
S
S
L
L
R
E
K
R
Site 94
S834
G
Y
E
H
E
L
S
S
L
L
R
E
K
R
Q
Site 95
Y869
M
A
K
A
R
E
Q
Y
E
A
E
E
R
K
Q
Site 96
T901
A
H
E
R
E
L
E
T
V
R
Q
E
Q
H
K
Site 97
S970
Q
R
Q
V
A
L
K
S
E
E
A
T
A
T
H
Site 98
T976
K
S
E
E
A
T
A
T
H
Q
Q
L
E
E
A
Site 99
S1013
A
R
K
L
K
L
E
S
Q
V
D
L
L
Q
A
Site 100
S1022
V
D
L
L
Q
A
Q
S
Q
Q
L
Q
K
H
F
Site 101
T1047
Q
H
L
L
R
E
V
T
V
E
E
N
N
A
S
Site 102
S1054
T
V
E
E
N
N
A
S
P
H
F
E
P
D
L
Site 103
S1069
H
I
E
D
L
R
K
S
L
G
T
N
Q
T
K
Site 104
T1075
K
S
L
G
T
N
Q
T
K
E
V
S
S
S
L
Site 105
S1079
T
N
Q
T
K
E
V
S
S
S
L
S
Q
S
K
Site 106
S1081
Q
T
K
E
V
S
S
S
L
S
Q
S
K
E
D
Site 107
S1083
K
E
V
S
S
S
L
S
Q
S
K
E
D
L
Y
Site 108
S1085
V
S
S
S
L
S
Q
S
K
E
D
L
Y
L
D
Site 109
Y1090
S
Q
S
K
E
D
L
Y
L
D
S
L
S
S
H
Site 110
S1093
K
E
D
L
Y
L
D
S
L
S
S
H
N
V
W
Site 111
S1095
D
L
Y
L
D
S
L
S
S
H
N
V
W
H
L
Site 112
S1123
F
L
V
Q
Q
T
R
S
M
R
R
R
Q
T
A
Site 113
T1129
R
S
M
R
R
R
Q
T
A
L
K
A
A
Q
Q
Site 114
S1144
H
W
R
H
E
L
A
S
A
Q
E
V
A
K
D
Site 115
S1177
R
H
L
D
E
M
K
S
A
M
R
K
G
H
N
Site 116
S1198
E
K
L
N
Q
L
E
S
S
L
W
E
E
A
S
Site 117
S1199
K
L
N
Q
L
E
S
S
L
W
E
E
A
S
D
Site 118
S1205
S
S
L
W
E
E
A
S
D
E
G
T
L
G
G
Site 119
T1209
E
E
A
S
D
E
G
T
L
G
G
S
P
T
K
Site 120
S1213
D
E
G
T
L
G
G
S
P
T
K
K
A
V
T
Site 121
T1215
G
T
L
G
G
S
P
T
K
K
A
V
T
F
D
Site 122
T1220
S
P
T
K
K
A
V
T
F
D
L
S
D
M
D
Site 123
S1224
K
A
V
T
F
D
L
S
D
M
D
S
L
S
S
Site 124
S1228
F
D
L
S
D
M
D
S
L
S
S
E
S
S
E
Site 125
S1230
L
S
D
M
D
S
L
S
S
E
S
S
E
S
F
Site 126
S1231
S
D
M
D
S
L
S
S
E
S
S
E
S
F
S
Site 127
S1233
M
D
S
L
S
S
E
S
S
E
S
F
S
P
P
Site 128
S1234
D
S
L
S
S
E
S
S
E
S
F
S
P
P
H
Site 129
S1236
L
S
S
E
S
S
E
S
F
S
P
P
H
R
E
Site 130
S1238
S
E
S
S
E
S
F
S
P
P
H
R
E
W
W
Site 131
S1252
W
R
Q
Q
R
I
D
S
T
P
S
L
T
S
R
Site 132
T1253
R
Q
Q
R
I
D
S
T
P
S
L
T
S
R
K
Site 133
S1255
Q
R
I
D
S
T
P
S
L
T
S
R
K
I
H
Site 134
T1257
I
D
S
T
P
S
L
T
S
R
K
I
H
G
L
Site 135
S1265
S
R
K
I
H
G
L
S
H
S
L
R
Q
I
S
Site 136
S1267
K
I
H
G
L
S
H
S
L
R
Q
I
S
S
Q
Site 137
S1272
S
H
S
L
R
Q
I
S
S
Q
L
S
S
V
L
Site 138
S1273
H
S
L
R
Q
I
S
S
Q
L
S
S
V
L
S
Site 139
S1284
S
V
L
S
I
L
D
S
L
N
P
Q
S
P
P
Site 140
S1289
L
D
S
L
N
P
Q
S
P
P
P
L
L
A
S
Site 141
S1308
L
P
P
R
D
P
K
S
T
P
T
P
T
Y
Y
Site 142
T1309
P
P
R
D
P
K
S
T
P
T
P
T
Y
Y
G
Site 143
T1311
R
D
P
K
S
T
P
T
P
T
Y
Y
G
S
L
Site 144
T1313
P
K
S
T
P
T
P
T
Y
Y
G
S
L
A
R
Site 145
Y1314
K
S
T
P
T
P
T
Y
Y
G
S
L
A
R
F
Site 146
Y1315
S
T
P
T
P
T
Y
Y
G
S
L
A
R
F
S
Site 147
S1317
P
T
P
T
Y
Y
G
S
L
A
R
F
S
A
L
Site 148
S1326
A
R
F
S
A
L
S
S
A
T
P
T
S
T
Q
Site 149
T1328
F
S
A
L
S
S
A
T
P
T
S
T
Q
W
A
Site 150
T1330
A
L
S
S
A
T
P
T
S
T
Q
W
A
W
D
Site 151
S1331
L
S
S
A
T
P
T
S
T
Q
W
A
W
D
S
Site 152
T1332
S
S
A
T
P
T
S
T
Q
W
A
W
D
S
G
Site 153
S1338
S
T
Q
W
A
W
D
S
G
Q
G
P
R
L
P
Site 154
S1346
G
Q
G
P
R
L
P
S
S
V
A
Q
T
V
D
Site 155
S1347
Q
G
P
R
L
P
S
S
V
A
Q
T
V
D
D
Site 156
Y1363
L
L
E
K
W
R
K
Y
F
P
S
G
I
P
L
Site 157
S1366
K
W
R
K
Y
F
P
S
G
I
P
L
L
S
N
Site 158
S1372
P
S
G
I
P
L
L
S
N
S
P
T
P
L
E
Site 159
S1374
G
I
P
L
L
S
N
S
P
T
P
L
E
S
R
Site 160
T1376
P
L
L
S
N
S
P
T
P
L
E
S
R
L
G
Site 161
S1380
N
S
P
T
P
L
E
S
R
L
G
Y
M
S
A
Site 162
Y1384
P
L
E
S
R
L
G
Y
M
S
A
S
E
Q
L
Site 163
S1386
E
S
R
L
G
Y
M
S
A
S
E
Q
L
R
L
Site 164
S1388
R
L
G
Y
M
S
A
S
E
Q
L
R
L
L
Q
Site 165
S1397
Q
L
R
L
L
Q
H
S
H
S
Q
V
P
E
A
Site 166
S1399
R
L
L
Q
H
S
H
S
Q
V
P
E
A
G
S
Site 167
S1406
S
Q
V
P
E
A
G
S
T
T
F
Q
G
I
I
Site 168
T1407
Q
V
P
E
A
G
S
T
T
F
Q
G
I
I
E
Site 169
S1433
D
P
R
L
P
L
F
S
S
T
P
K
P
K
A
Site 170
S1434
P
R
L
P
L
F
S
S
T
P
K
P
K
A
T
Site 171
T1435
R
L
P
L
F
S
S
T
P
K
P
K
A
T
L
Site 172
T1441
S
T
P
K
P
K
A
T
L
S
L
L
Q
L
G
Site 173
S1443
P
K
P
K
A
T
L
S
L
L
Q
L
G
L
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation