KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
SMG5
Full Name:
Alias:
EST1-like protein B;LPTS-RP1;LPTS-interacting protein;SMG-5 homolog
Type:
Mass (Da):
113928
Number AA:
1016
UniProt ID:
Q9UPR3
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T7
_
M
S
Q
G
P
P
T
G
E
S
S
E
P
E
Site 2
S11
G
P
P
T
G
E
S
S
E
P
E
A
K
V
L
Site 3
Y44
I
L
C
N
K
T
A
Y
Q
E
V
F
K
P
E
Site 4
S54
V
F
K
P
E
N
I
S
L
R
N
K
L
R
E
Site 5
Y74
M
F
L
H
P
V
D
Y
G
R
K
A
E
E
L
Site 6
T96
E
V
I
Q
L
I
K
T
N
K
K
H
I
H
S
Site 7
T106
K
H
I
H
S
R
S
T
L
E
C
A
Y
R
T
Site 8
Y128
F
Y
Q
H
L
L
L
Y
I
Q
S
H
Y
Q
L
Site 9
S158
I
G
C
K
K
P
V
S
A
S
G
K
E
M
D
Site 10
T220
M
P
F
N
Q
L
G
T
L
A
G
S
K
Y
Y
Site 11
Y226
G
T
L
A
G
S
K
Y
Y
N
V
E
A
M
Y
Site 12
Y235
N
V
E
A
M
Y
C
Y
L
R
C
I
Q
S
E
Site 13
S244
R
C
I
Q
S
E
V
S
F
E
G
A
Y
G
N
Site 14
Y256
Y
G
N
L
K
R
L
Y
D
K
A
A
K
M
Y
Site 15
T271
H
Q
L
K
K
C
E
T
R
K
L
S
P
G
K
Site 16
S275
K
C
E
T
R
K
L
S
P
G
K
K
R
C
K
Site 17
S296
V
N
F
M
Y
L
Q
S
L
L
Q
P
K
S
S
Site 18
S302
Q
S
L
L
Q
P
K
S
S
S
V
D
S
E
L
Site 19
S303
S
L
L
Q
P
K
S
S
S
V
D
S
E
L
T
Site 20
S304
L
L
Q
P
K
S
S
S
V
D
S
E
L
T
S
Site 21
S307
P
K
S
S
S
V
D
S
E
L
T
S
L
C
Q
Site 22
S334
L
P
S
S
P
N
L
S
L
A
S
E
D
E
E
Site 23
Y343
A
S
E
D
E
E
E
Y
E
S
G
Y
A
F
L
Site 24
S345
E
D
E
E
E
Y
E
S
G
Y
A
F
L
P
D
Site 25
S374
H
S
L
E
R
A
G
S
K
Q
Y
S
A
A
I
Site 26
T418
P
A
F
Q
S
D
G
T
D
E
P
E
S
K
E
Site 27
S423
D
G
T
D
E
P
E
S
K
E
P
V
E
K
E
Site 28
T441
D
P
E
P
P
P
V
T
P
Q
V
G
E
G
R
Site 29
S450
Q
V
G
E
G
R
K
S
R
K
F
S
R
L
S
Site 30
S454
G
R
K
S
R
K
F
S
R
L
S
C
L
R
R
Site 31
S457
S
R
K
F
S
R
L
S
C
L
R
R
R
R
H
Site 32
S472
P
P
K
V
G
D
D
S
D
L
S
E
G
F
E
Site 33
S475
V
G
D
D
S
D
L
S
E
G
F
E
S
D
S
Site 34
S480
D
L
S
E
G
F
E
S
D
S
S
H
D
S
A
Site 35
S482
S
E
G
F
E
S
D
S
S
H
D
S
A
R
A
Site 36
S483
E
G
F
E
S
D
S
S
H
D
S
A
R
A
S
Site 37
S486
E
S
D
S
S
H
D
S
A
R
A
S
E
G
S
Site 38
S490
S
H
D
S
A
R
A
S
E
G
S
D
S
G
S
Site 39
S493
S
A
R
A
S
E
G
S
D
S
G
S
D
K
S
Site 40
S495
R
A
S
E
G
S
D
S
G
S
D
K
S
L
E
Site 41
S497
S
E
G
S
D
S
G
S
D
K
S
L
E
G
G
Site 42
S500
S
D
S
G
S
D
K
S
L
E
G
G
G
T
A
Site 43
T506
K
S
L
E
G
G
G
T
A
F
D
A
E
T
D
Site 44
T512
G
T
A
F
D
A
E
T
D
S
E
M
N
S
Q
Site 45
S514
A
F
D
A
E
T
D
S
E
M
N
S
Q
E
S
Site 46
S518
E
T
D
S
E
M
N
S
Q
E
S
R
S
D
L
Site 47
T534
D
M
E
E
E
E
G
T
R
S
P
T
L
E
P
Site 48
S536
E
E
E
E
G
T
R
S
P
T
L
E
P
P
R
Site 49
T538
E
E
G
T
R
S
P
T
L
E
P
P
R
G
R
Site 50
S546
L
E
P
P
R
G
R
S
E
A
P
D
S
L
N
Site 51
S551
G
R
S
E
A
P
D
S
L
N
G
P
L
G
P
Site 52
S559
L
N
G
P
L
G
P
S
E
A
S
I
A
S
N
Site 53
S562
P
L
G
P
S
E
A
S
I
A
S
N
L
Q
A
Site 54
S571
A
S
N
L
Q
A
M
S
T
Q
M
F
Q
T
K
Site 55
T572
S
N
L
Q
A
M
S
T
Q
M
F
Q
T
K
R
Site 56
T595
S
N
L
L
L
Q
P
T
T
N
P
H
T
S
A
Site 57
T596
N
L
L
L
Q
P
T
T
N
P
H
T
S
A
S
Site 58
S601
P
T
T
N
P
H
T
S
A
S
H
R
P
C
V
Site 59
S603
T
N
P
H
T
S
A
S
H
R
P
C
V
N
G
Site 60
S616
N
G
D
V
D
K
P
S
E
P
A
S
E
E
G
Site 61
S620
D
K
P
S
E
P
A
S
E
E
G
S
E
S
E
Site 62
S624
E
P
A
S
E
E
G
S
E
S
E
G
S
E
S
Site 63
S626
A
S
E
E
G
S
E
S
E
G
S
E
S
S
G
Site 64
S629
E
G
S
E
S
E
G
S
E
S
S
G
R
S
C
Site 65
S631
S
E
S
E
G
S
E
S
S
G
R
S
C
R
N
Site 66
S632
E
S
E
G
S
E
S
S
G
R
S
C
R
N
E
Site 67
S635
G
S
E
S
S
G
R
S
C
R
N
E
R
S
I
Site 68
S641
R
S
C
R
N
E
R
S
I
Q
E
K
L
Q
V
Site 69
S681
V
C
A
Q
S
S
Q
S
L
W
N
R
L
S
V
Site 70
S724
C
E
L
P
D
L
P
S
S
L
L
L
P
E
D
Site 71
S725
E
L
P
D
L
P
S
S
L
L
L
P
E
D
M
Site 72
T751
H
R
R
F
N
F
D
T
D
R
P
L
L
S
T
Site 73
S757
D
T
D
R
P
L
L
S
T
L
E
E
S
V
V
Site 74
T758
T
D
R
P
L
L
S
T
L
E
E
S
V
V
R
Site 75
S795
P
E
V
G
I
F
V
S
I
A
Q
S
E
Q
E
Site 76
S803
I
A
Q
S
E
Q
E
S
L
L
Q
Q
A
Q
A
Site 77
S838
L
R
L
Q
L
E
V
S
Q
L
E
G
S
L
Q
Site 78
S851
L
Q
Q
P
K
A
Q
S
A
M
S
P
Y
L
V
Site 79
S854
P
K
A
Q
S
A
M
S
P
Y
L
V
P
D
T
Site 80
Y856
A
Q
S
A
M
S
P
Y
L
V
P
D
T
Q
A
Site 81
T861
S
P
Y
L
V
P
D
T
Q
A
L
C
H
H
L
Site 82
Y908
G
A
R
D
G
I
R
Y
L
E
A
E
F
K
K
Site 83
Y919
E
F
K
K
G
N
R
Y
I
R
C
Q
K
E
V
Site 84
S929
C
Q
K
E
V
G
K
S
F
E
R
H
K
L
K
Site 85
T944
R
Q
D
A
D
A
W
T
L
Y
K
I
L
D
S
Site 86
Y946
D
A
D
A
W
T
L
Y
K
I
L
D
S
C
K
Site 87
T956
L
D
S
C
K
Q
L
T
L
A
Q
G
A
G
E
Site 88
S982
G
L
P
L
D
N
P
S
V
L
S
G
P
M
Q
Site 89
Y1009
I
K
N
V
L
D
F
Y
K
Q
W
K
E
I
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation