KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
KIAA1107
Full Name:
Uncharacterized protein KIAA1107
Alias:
LOC23285
Type:
Unknown function
Mass (Da):
155681
Number AA:
1409
UniProt ID:
Q9UPP5
International Prot ID:
IPI00298902
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
E
S
D
R
L
I
I
S
L
P
R
V
K
W
T
Site 2
T21
K
W
T
E
A
A
L
T
M
A
S
Q
L
Q
E
Site 3
T65
S
T
A
D
L
L
D
T
I
L
K
A
I
E
E
Site 4
T75
K
A
I
E
E
N
I
T
T
E
N
S
C
S
L
Site 5
T76
A
I
E
E
N
I
T
T
E
N
S
C
S
L
L
Site 6
S92
A
L
D
T
L
L
N
S
D
S
T
K
E
M
G
Site 7
S94
D
T
L
L
N
S
D
S
T
K
E
M
G
F
T
Site 8
T95
T
L
L
N
S
D
S
T
K
E
M
G
F
T
C
Site 9
T101
S
T
K
E
M
G
F
T
C
K
I
Q
A
L
R
Site 10
T125
S
F
Y
A
V
R
H
T
E
S
W
K
L
M
S
Site 11
S159
L
G
K
K
P
I
F
S
S
S
Q
Q
R
K
Q
Site 12
S161
K
K
P
I
F
S
S
S
Q
Q
R
K
Q
V
S
Site 13
S168
S
Q
Q
R
K
Q
V
S
D
S
G
D
I
K
I
Site 14
S170
Q
R
K
Q
V
S
D
S
G
D
I
K
I
K
S
Site 15
S177
S
G
D
I
K
I
K
S
W
R
G
N
N
K
K
Site 16
Y189
N
K
K
E
C
W
S
Y
L
S
T
N
K
K
M
Site 17
T192
E
C
W
S
Y
L
S
T
N
K
K
M
K
S
D
Site 18
S198
S
T
N
K
K
M
K
S
D
G
L
G
A
S
G
Site 19
S204
K
S
D
G
L
G
A
S
G
H
S
S
S
T
N
Site 20
S208
L
G
A
S
G
H
S
S
S
T
N
R
N
S
I
Site 21
S209
G
A
S
G
H
S
S
S
T
N
R
N
S
I
N
Site 22
T210
A
S
G
H
S
S
S
T
N
R
N
S
I
N
K
Site 23
S214
S
S
S
T
N
R
N
S
I
N
K
T
L
K
Q
Site 24
T218
N
R
N
S
I
N
K
T
L
K
Q
D
D
V
K
Site 25
T230
D
V
K
E
K
D
G
T
K
I
A
S
K
I
T
Site 26
S248
K
T
G
G
K
N
V
S
G
K
P
K
T
V
T
Site 27
T253
N
V
S
G
K
P
K
T
V
T
K
S
K
T
E
Site 28
T255
S
G
K
P
K
T
V
T
K
S
K
T
E
N
G
Site 29
S257
K
P
K
T
V
T
K
S
K
T
E
N
G
D
K
Site 30
T259
K
T
V
T
K
S
K
T
E
N
G
D
K
A
R
Site 31
S271
K
A
R
L
E
N
M
S
P
R
Q
V
V
E
R
Site 32
S306
R
N
Q
E
G
Q
I
S
G
A
R
P
K
V
L
Site 33
T314
G
A
R
P
K
V
L
T
G
N
L
N
V
Q
A
Site 34
T330
A
K
P
L
K
K
A
T
G
K
D
S
P
C
L
Site 35
S334
K
K
A
T
G
K
D
S
P
C
L
S
I
A
G
Site 36
S338
G
K
D
S
P
C
L
S
I
A
G
P
S
S
R
Site 37
S343
C
L
S
I
A
G
P
S
S
R
S
T
D
S
S
Site 38
S344
L
S
I
A
G
P
S
S
R
S
T
D
S
S
M
Site 39
S346
I
A
G
P
S
S
R
S
T
D
S
S
M
E
F
Site 40
T347
A
G
P
S
S
R
S
T
D
S
S
M
E
F
S
Site 41
S349
P
S
S
R
S
T
D
S
S
M
E
F
S
I
S
Site 42
S350
S
S
R
S
T
D
S
S
M
E
F
S
I
S
T
Site 43
S354
T
D
S
S
M
E
F
S
I
S
T
E
C
L
D
Site 44
S356
S
S
M
E
F
S
I
S
T
E
C
L
D
E
P
Site 45
T369
E
P
K
E
N
G
S
T
E
E
E
K
P
S
G
Site 46
S375
S
T
E
E
E
K
P
S
G
H
K
L
S
F
C
Site 47
S380
K
P
S
G
H
K
L
S
F
C
D
S
P
G
Q
Site 48
S384
H
K
L
S
F
C
D
S
P
G
Q
M
M
K
N
Site 49
S392
P
G
Q
M
M
K
N
S
V
D
S
V
K
N
S
Site 50
S395
M
M
K
N
S
V
D
S
V
K
N
S
T
V
A
Site 51
S399
S
V
D
S
V
K
N
S
T
V
A
I
K
S
R
Site 52
T400
V
D
S
V
K
N
S
T
V
A
I
K
S
R
P
Site 53
S405
N
S
T
V
A
I
K
S
R
P
V
S
R
V
T
Site 54
S409
A
I
K
S
R
P
V
S
R
V
T
N
G
T
S
Site 55
T412
S
R
P
V
S
R
V
T
N
G
T
S
N
K
K
Site 56
T415
V
S
R
V
T
N
G
T
S
N
K
K
S
I
H
Site 57
S416
S
R
V
T
N
G
T
S
N
K
K
S
I
H
E
Site 58
S420
N
G
T
S
N
K
K
S
I
H
E
Q
D
T
N
Site 59
S442
K
V
S
G
K
G
C
S
E
P
V
P
Q
A
I
Site 60
T455
A
I
L
K
K
R
G
T
S
N
G
C
T
A
A
Site 61
S456
I
L
K
K
R
G
T
S
N
G
C
T
A
A
Q
Site 62
T460
R
G
T
S
N
G
C
T
A
A
Q
Q
R
T
K
Site 63
S468
A
A
Q
Q
R
T
K
S
T
P
S
N
L
T
K
Site 64
T469
A
Q
Q
R
T
K
S
T
P
S
N
L
T
K
T
Site 65
T476
T
P
S
N
L
T
K
T
Q
G
S
Q
G
E
S
Site 66
S479
N
L
T
K
T
Q
G
S
Q
G
E
S
P
N
S
Site 67
S483
T
Q
G
S
Q
G
E
S
P
N
S
V
K
S
S
Site 68
S486
S
Q
G
E
S
P
N
S
V
K
S
S
V
S
S
Site 69
S489
E
S
P
N
S
V
K
S
S
V
S
S
R
Q
S
Site 70
S490
S
P
N
S
V
K
S
S
V
S
S
R
Q
S
D
Site 71
S492
N
S
V
K
S
S
V
S
S
R
Q
S
D
E
N
Site 72
S493
S
V
K
S
S
V
S
S
R
Q
S
D
E
N
V
Site 73
S496
S
S
V
S
S
R
Q
S
D
E
N
V
A
K
L
Site 74
S554
E
T
L
N
N
K
D
S
K
Q
K
M
P
P
G
Site 75
S565
M
P
P
G
Q
V
I
S
K
T
Q
P
S
S
Q
Site 76
T567
P
G
Q
V
I
S
K
T
Q
P
S
S
Q
R
P
Site 77
S570
V
I
S
K
T
Q
P
S
S
Q
R
P
L
K
H
Site 78
S571
I
S
K
T
Q
P
S
S
Q
R
P
L
K
H
E
Site 79
S580
R
P
L
K
H
E
T
S
T
V
Q
K
S
M
F
Site 80
T581
P
L
K
H
E
T
S
T
V
Q
K
S
M
F
H
Site 81
S598
R
D
N
N
N
K
D
S
V
S
E
Q
K
P
H
Site 82
S600
N
N
N
K
D
S
V
S
E
Q
K
P
H
K
P
Site 83
S616
I
N
L
A
S
E
I
S
D
A
E
A
L
Q
S
Site 84
S623
S
D
A
E
A
L
Q
S
S
C
R
P
D
P
Q
Site 85
S624
D
A
E
A
L
Q
S
S
C
R
P
D
P
Q
K
Site 86
S654
N
I
S
K
L
D
K
S
L
K
H
E
L
E
S
Site 87
T671
I
C
L
D
K
S
E
T
K
F
P
N
H
K
E
Site 88
S699
V
G
S
D
N
V
N
S
K
F
Y
S
T
T
A
Site 89
Y709
Y
S
T
T
A
L
K
Y
M
V
S
N
P
N
E
Site 90
S712
T
A
L
K
Y
M
V
S
N
P
N
E
N
S
L
Site 91
S718
V
S
N
P
N
E
N
S
L
N
S
N
P
V
C
Site 92
S729
N
P
V
C
D
L
D
S
T
S
A
G
Q
I
H
Site 93
S739
A
G
Q
I
H
L
I
S
D
R
E
N
Q
V
G
Site 94
T750
N
Q
V
G
R
K
D
T
N
K
Q
S
S
I
K
Site 95
S755
K
D
T
N
K
Q
S
S
I
K
C
V
E
D
V
Site 96
S763
I
K
C
V
E
D
V
S
L
C
N
P
E
R
T
Site 97
S776
R
T
N
G
T
L
N
S
A
Q
E
D
K
K
S
Site 98
S783
S
A
Q
E
D
K
K
S
K
V
P
V
E
G
L
Site 99
T791
K
V
P
V
E
G
L
T
I
P
S
K
L
S
D
Site 100
S797
L
T
I
P
S
K
L
S
D
E
S
A
M
D
E
Site 101
S800
P
S
K
L
S
D
E
S
A
M
D
E
D
K
H
Site 102
S812
D
K
H
A
T
A
D
S
D
V
S
S
K
C
F
Site 103
S815
A
T
A
D
S
D
V
S
S
K
C
F
S
G
Q
Site 104
S816
T
A
D
S
D
V
S
S
K
C
F
S
G
Q
L
Site 105
S820
D
V
S
S
K
C
F
S
G
Q
L
S
E
K
N
Site 106
S824
K
C
F
S
G
Q
L
S
E
K
N
S
P
K
N
Site 107
S828
G
Q
L
S
E
K
N
S
P
K
N
M
E
T
S
Site 108
S835
S
P
K
N
M
E
T
S
E
S
P
E
S
H
E
Site 109
S837
K
N
M
E
T
S
E
S
P
E
S
H
E
T
P
Site 110
S840
E
T
S
E
S
P
E
S
H
E
T
P
E
T
P
Site 111
T843
E
S
P
E
S
H
E
T
P
E
T
P
F
V
G
Site 112
T846
E
S
H
E
T
P
E
T
P
F
V
G
H
W
N
Site 113
S864
G
V
L
H
Q
R
E
S
P
E
S
D
T
G
S
Site 114
S867
H
Q
R
E
S
P
E
S
D
T
G
S
A
T
T
Site 115
T869
R
E
S
P
E
S
D
T
G
S
A
T
T
S
S
Site 116
S871
S
P
E
S
D
T
G
S
A
T
T
S
S
D
D
Site 117
S875
D
T
G
S
A
T
T
S
S
D
D
I
K
P
R
Site 118
S876
T
G
S
A
T
T
S
S
D
D
I
K
P
R
S
Site 119
S883
S
D
D
I
K
P
R
S
E
D
Y
D
A
G
G
Site 120
Y886
I
K
P
R
S
E
D
Y
D
A
G
G
S
Q
D
Site 121
S891
E
D
Y
D
A
G
G
S
Q
D
D
D
G
S
N
Site 122
S897
G
S
Q
D
D
D
G
S
N
D
R
G
I
S
K
Site 123
S903
G
S
N
D
R
G
I
S
K
C
G
T
M
L
C
Site 124
S917
C
H
D
F
L
G
R
S
S
S
D
T
S
T
P
Site 125
S918
H
D
F
L
G
R
S
S
S
D
T
S
T
P
E
Site 126
S919
D
F
L
G
R
S
S
S
D
T
S
T
P
E
E
Site 127
T921
L
G
R
S
S
S
D
T
S
T
P
E
E
L
K
Site 128
S922
G
R
S
S
S
D
T
S
T
P
E
E
L
K
I
Site 129
T923
R
S
S
S
D
T
S
T
P
E
E
L
K
I
Y
Site 130
Y930
T
P
E
E
L
K
I
Y
D
S
N
L
R
I
E
Site 131
S932
E
E
L
K
I
Y
D
S
N
L
R
I
E
V
K
Site 132
S953
N
D
L
F
Q
V
N
S
T
S
D
D
E
I
P
Site 133
S955
L
F
Q
V
N
S
T
S
D
D
E
I
P
R
K
Site 134
S968
R
K
R
P
E
I
W
S
R
S
A
I
V
H
S
Site 135
S970
R
P
E
I
W
S
R
S
A
I
V
H
S
R
E
Site 136
S975
S
R
S
A
I
V
H
S
R
E
R
E
N
I
P
Site 137
S985
R
E
N
I
P
R
G
S
V
Q
F
A
Q
E
I
Site 138
S998
E
I
D
Q
V
S
S
S
A
D
E
T
E
D
E
Site 139
T1002
V
S
S
S
A
D
E
T
E
D
E
R
S
E
A
Site 140
S1007
D
E
T
E
D
E
R
S
E
A
E
N
V
A
E
Site 141
S1019
V
A
E
N
F
S
I
S
N
P
A
P
Q
Q
F
Site 142
S1046
E
N
E
C
R
E
F
S
A
N
K
K
F
K
R
Site 143
S1054
A
N
K
K
F
K
R
S
V
L
L
S
V
D
E
Site 144
S1058
F
K
R
S
V
L
L
S
V
D
E
C
E
E
L
Site 145
S1067
D
E
C
E
E
L
G
S
D
E
G
E
V
H
T
Site 146
T1074
S
D
E
G
E
V
H
T
P
F
Q
A
S
V
D
Site 147
S1079
V
H
T
P
F
Q
A
S
V
D
S
F
S
P
S
Site 148
S1082
P
F
Q
A
S
V
D
S
F
S
P
S
D
V
F
Site 149
S1084
Q
A
S
V
D
S
F
S
P
S
D
V
F
D
G
Site 150
S1086
S
V
D
S
F
S
P
S
D
V
F
D
G
I
S
Site 151
S1093
S
D
V
F
D
G
I
S
H
E
H
H
G
R
T
Site 152
T1100
S
H
E
H
H
G
R
T
C
Y
S
R
F
S
R
Site 153
Y1102
E
H
H
G
R
T
C
Y
S
R
F
S
R
E
S
Site 154
S1106
R
T
C
Y
S
R
F
S
R
E
S
E
D
N
I
Site 155
S1109
Y
S
R
F
S
R
E
S
E
D
N
I
L
E
C
Site 156
S1123
C
K
Q
N
K
G
N
S
V
C
K
N
E
S
T
Site 157
S1129
N
S
V
C
K
N
E
S
T
V
L
D
L
S
S
Site 158
S1135
E
S
T
V
L
D
L
S
S
I
D
S
S
R
K
Site 159
S1136
S
T
V
L
D
L
S
S
I
D
S
S
R
K
N
Site 160
S1139
L
D
L
S
S
I
D
S
S
R
K
N
K
Q
S
Site 161
S1140
D
L
S
S
I
D
S
S
R
K
N
K
Q
S
V
Site 162
S1146
S
S
R
K
N
K
Q
S
V
S
A
T
E
K
K
Site 163
S1148
R
K
N
K
Q
S
V
S
A
T
E
K
K
N
T
Site 164
T1150
N
K
Q
S
V
S
A
T
E
K
K
N
T
I
D
Site 165
T1155
S
A
T
E
K
K
N
T
I
D
V
L
S
S
R
Site 166
S1160
K
N
T
I
D
V
L
S
S
R
S
R
Q
L
L
Site 167
S1161
N
T
I
D
V
L
S
S
R
S
R
Q
L
L
R
Site 168
S1163
I
D
V
L
S
S
R
S
R
Q
L
L
R
E
D
Site 169
S1192
Q
R
S
K
F
L
D
S
D
V
K
S
Q
E
R
Site 170
S1196
F
L
D
S
D
V
K
S
Q
E
R
P
C
H
L
Site 171
S1212
L
H
Q
R
E
P
N
S
D
I
P
K
N
S
S
Site 172
S1218
N
S
D
I
P
K
N
S
S
T
K
S
L
D
S
Site 173
S1219
S
D
I
P
K
N
S
S
T
K
S
L
D
S
F
Site 174
T1220
D
I
P
K
N
S
S
T
K
S
L
D
S
F
R
Site 175
S1222
P
K
N
S
S
T
K
S
L
D
S
F
R
S
Q
Site 176
S1225
S
S
T
K
S
L
D
S
F
R
S
Q
V
L
P
Site 177
S1228
K
S
L
D
S
F
R
S
Q
V
L
P
Q
E
G
Site 178
S1242
G
P
V
K
E
S
H
S
T
T
T
E
K
A
N
Site 179
T1244
V
K
E
S
H
S
T
T
T
E
K
A
N
I
A
Site 180
Y1269
T
L
A
Q
T
R
M
Y
D
H
R
P
S
K
T
Site 181
S1274
R
M
Y
D
H
R
P
S
K
T
L
S
P
I
Y
Site 182
T1276
Y
D
H
R
P
S
K
T
L
S
P
I
Y
E
M
Site 183
S1278
H
R
P
S
K
T
L
S
P
I
Y
E
M
D
V
Site 184
Y1281
S
K
T
L
S
P
I
Y
E
M
D
V
I
E
A
Site 185
T1300
V
E
S
E
T
H
V
T
D
M
D
F
E
D
D
Site 186
T1316
H
F
A
K
Q
D
W
T
L
L
K
Q
L
L
S
Site 187
S1323
T
L
L
K
Q
L
L
S
E
Q
D
S
N
L
D
Site 188
S1327
Q
L
L
S
E
Q
D
S
N
L
D
V
T
N
S
Site 189
T1332
Q
D
S
N
L
D
V
T
N
S
V
P
E
D
L
Site 190
S1334
S
N
L
D
V
T
N
S
V
P
E
D
L
S
L
Site 191
S1340
N
S
V
P
E
D
L
S
L
A
Q
Y
L
I
N
Site 192
S1356
T
L
L
L
A
R
D
S
S
K
P
Q
G
I
T
Site 193
S1357
L
L
L
A
R
D
S
S
K
P
Q
G
I
T
H
Site 194
T1367
Q
G
I
T
H
I
D
T
L
N
R
W
S
E
L
Site 195
S1372
I
D
T
L
N
R
W
S
E
L
T
S
P
L
D
Site 196
T1375
L
N
R
W
S
E
L
T
S
P
L
D
S
S
A
Site 197
S1376
N
R
W
S
E
L
T
S
P
L
D
S
S
A
S
Site 198
T1385
L
D
S
S
A
S
I
T
M
A
S
F
S
S
E
Site 199
S1388
S
A
S
I
T
M
A
S
F
S
S
E
D
C
S
Site 200
S1390
S
I
T
M
A
S
F
S
S
E
D
C
S
P
Q
Site 201
S1391
I
T
M
A
S
F
S
S
E
D
C
S
P
Q
G
Site 202
S1395
S
F
S
S
E
D
C
S
P
Q
G
E
W
T
I
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation