KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
SAPS1
Full Name:
Serine/threonine-protein phosphatase 6 regulatory subunit 1
Alias:
KIAA1115; Protein phosphatase 6, regulatory subunit 1; SAP190; SAPS domain family member 1; SAPS domain family, member 1
Type:
Unknown function
Mass (Da):
96724
Number AA:
881
UniProt ID:
Q9UPN7
International Prot ID:
IPI00402008
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0044424
GO:0044464
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0005515
GO:0019899
PhosphoSite+
KinaseNET
Biological Process:
GO:0043666
GO:0050790
GO:0051336
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
K
F
D
L
H
T
S
S
H
L
D
T
L
L
E
Site 2
T15
H
T
S
S
H
L
D
T
L
L
E
R
E
D
L
Site 3
S23
L
L
E
R
E
D
L
S
L
P
E
L
L
D
E
Site 4
T62
Q
A
M
V
A
W
V
T
Q
E
P
P
D
S
G
Site 5
S68
V
T
Q
E
P
P
D
S
G
E
E
R
L
R
Y
Site 6
Y75
S
G
E
E
R
L
R
Y
K
Y
P
S
V
A
C
Site 7
Y77
E
E
R
L
R
Y
K
Y
P
S
V
A
C
E
I
Site 8
S79
R
L
R
Y
K
Y
P
S
V
A
C
E
I
L
T
Site 9
S101
D
A
L
G
A
D
E
S
L
L
N
R
L
Y
G
Site 10
Y107
E
S
L
L
N
R
L
Y
G
F
L
Q
S
T
G
Site 11
S112
R
L
Y
G
F
L
Q
S
T
G
S
L
N
P
L
Site 12
S141
R
K
T
D
Q
L
V
S
F
L
R
K
K
D
D
Site 13
S202
L
I
E
Q
I
H
P
S
K
D
E
N
Q
H
S
Site 14
S209
S
K
D
E
N
Q
H
S
N
A
S
Q
S
L
C
Site 15
S212
E
N
Q
H
S
N
A
S
Q
S
L
C
D
I
I
Site 16
S214
Q
H
S
N
A
S
Q
S
L
C
D
I
I
R
L
Site 17
S232
Q
M
I
Q
V
Q
D
S
P
E
P
D
Q
L
L
Site 18
T247
A
T
L
E
K
Q
E
T
I
E
Q
L
L
S
N
Site 19
S253
E
T
I
E
Q
L
L
S
N
M
F
E
G
E
Q
Site 20
S261
N
M
F
E
G
E
Q
S
Q
S
V
I
V
S
G
Site 21
S263
F
E
G
E
Q
S
Q
S
V
I
V
S
G
I
Q
Site 22
S283
L
E
P
R
R
P
R
S
E
S
V
T
V
N
S
Site 23
S285
P
R
R
P
R
S
E
S
V
T
V
N
S
F
F
Site 24
T287
R
P
R
S
E
S
V
T
V
N
S
F
F
S
S
Site 25
S290
S
E
S
V
T
V
N
S
F
F
S
S
V
D
G
Site 26
S419
S
L
G
P
P
P
D
S
S
P
E
T
P
I
Q
Site 27
S420
L
G
P
P
P
D
S
S
P
E
T
P
I
Q
N
Site 28
T423
P
P
D
S
S
P
E
T
P
I
Q
N
P
V
V
Site 29
T445
R
L
V
E
R
I
L
T
S
W
E
E
N
D
R
Site 30
S446
L
V
E
R
I
L
T
S
W
E
E
N
D
R
V
Site 31
Y463
A
G
G
P
R
K
G
Y
M
G
H
L
T
R
V
Site 32
S496
Q
L
L
K
E
L
P
S
E
Q
Q
E
Q
W
E
Site 33
S507
E
Q
W
E
A
F
V
S
G
P
L
A
E
T
N
Site 34
T524
N
M
V
D
L
V
N
T
H
H
L
H
S
S
S
Site 35
S529
V
N
T
H
H
L
H
S
S
S
D
D
E
D
D
Site 36
S530
N
T
H
H
L
H
S
S
S
D
D
E
D
D
R
Site 37
S531
T
H
H
L
H
S
S
S
D
D
E
D
D
R
L
Site 38
S582
E
F
G
E
Q
E
E
S
V
N
A
P
F
D
K
Site 39
S596
K
T
A
N
I
T
F
S
L
N
A
D
D
E
N
Site 40
Y613
A
N
L
L
E
I
C
Y
K
D
R
I
Q
Q
F
Site 41
S635
D
E
E
E
A
Q
G
S
G
E
S
D
G
E
D
Site 42
S638
E
A
Q
G
S
G
E
S
D
G
E
D
G
A
W
Site 43
S648
E
D
G
A
W
Q
G
S
Q
L
A
R
G
A
R
Site 44
S664
G
Q
P
P
G
V
R
S
G
G
S
T
D
S
E
Site 45
S667
P
G
V
R
S
G
G
S
T
D
S
E
D
E
E
Site 46
T668
G
V
R
S
G
G
S
T
D
S
E
D
E
E
E
Site 47
S670
R
S
G
G
S
T
D
S
E
D
E
E
E
E
D
Site 48
T696
C
A
A
R
G
G
A
T
P
L
S
Y
P
S
P
Site 49
S699
R
G
G
A
T
P
L
S
Y
P
S
P
G
P
Q
Site 50
Y700
G
G
A
T
P
L
S
Y
P
S
P
G
P
Q
P
Site 51
S702
A
T
P
L
S
Y
P
S
P
G
P
Q
P
P
G
Site 52
S711
G
P
Q
P
P
G
P
S
W
T
A
T
F
D
P
Site 53
T715
P
G
P
S
W
T
A
T
F
D
P
V
P
T
D
Site 54
T721
A
T
F
D
P
V
P
T
D
A
P
T
S
P
R
Site 55
T725
P
V
P
T
D
A
P
T
S
P
R
V
S
G
E
Site 56
S726
G
Q
P
P
G
V
R
S
G
G
S
T
D
S
E
Site 57
S730
A
P
T
S
P
R
V
S
G
E
E
E
L
H
T
Site 58
T737
S
G
E
E
E
L
H
T
G
P
P
A
P
Q
G
Site 59
S747
P
A
P
Q
G
P
L
S
V
P
Q
G
L
P
T
Site 60
T754
S
V
P
Q
G
L
P
T
Q
S
L
A
S
P
P
Site 61
S756
P
Q
G
L
P
T
Q
S
L
A
S
P
P
A
R
Site 62
S759
L
P
T
Q
S
L
A
S
P
P
A
R
D
A
L
Site 63
S770
R
D
A
L
Q
L
R
S
Q
D
P
T
P
P
S
Site 64
T774
Q
L
R
S
Q
D
P
T
P
P
S
A
P
Q
E
Site 65
S777
S
Q
D
P
T
P
P
S
A
P
Q
E
A
T
E
Site 66
T807
S
I
G
D
L
Q
A
T
F
H
G
I
R
S
A
Site 67
S813
A
T
F
H
G
I
R
S
A
P
S
S
S
D
S
Site 68
S816
H
G
I
R
S
A
P
S
S
S
D
S
A
T
R
Site 69
S817
G
I
R
S
A
P
S
S
S
D
S
A
T
R
D
Site 70
S818
I
R
S
A
P
S
S
S
D
S
A
T
R
D
P
Site 71
S820
S
A
P
S
S
S
D
S
A
T
R
D
P
S
T
Site 72
T822
P
S
S
S
D
S
A
T
R
D
P
S
T
S
V
Site 73
S826
D
S
A
T
R
D
P
S
T
S
V
P
A
S
G
Site 74
T827
S
A
T
R
D
P
S
T
S
V
P
A
S
G
A
Site 75
S828
A
T
R
D
P
S
T
S
V
P
A
S
G
A
H
Site 76
S832
P
S
T
S
V
P
A
S
G
A
H
Q
P
P
Q
Site 77
T840
G
A
H
Q
P
P
Q
T
T
E
G
E
K
S
P
Site 78
S846
Q
T
T
E
G
E
K
S
P
E
P
L
G
L
P
Site 79
S855
E
P
L
G
L
P
Q
S
Q
S
A
Q
A
L
T
Site 80
S857
L
G
L
P
Q
S
Q
S
A
Q
A
L
T
P
P
Site 81
T862
S
Q
S
A
Q
A
L
T
P
P
P
I
P
N
G
Site 82
S870
P
P
P
I
P
N
G
S
A
P
E
G
P
A
S
Site 83
S877
S
A
P
E
G
P
A
S
P
G
S
Q
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation