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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
AZI1
Full Name:
ISOFORM 1 OF 5-AZACYTIDINE-INDUCED PROTEIN 1.
Alias:
5-azacytidine induced 1; 5-azacytidine-induced 1; 5-azacytidine-induced protein 1; AZ1; Centrosomal protein of 131 kDa; Cep131; KIAA1118; Pre-acrosome localization 1; Pre-acrosome localization protein 1; Putative uncharacterized protein AZI1
Type:
Calcium-binding protein
Mass (Da):
122061
Number AA:
1083
UniProt ID:
Q9UPN4
International Prot ID:
IPI00298883
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005813
GO:0005829
GO:0043226
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0030154
GO:0007275
GO:0007283
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S9
K
G
T
R
A
I
G
S
V
P
E
R
S
P
A
Site 2
S14
I
G
S
V
P
E
R
S
P
A
G
V
D
L
S
Site 3
S30
T
G
L
P
P
P
V
S
R
R
P
G
S
A
A
Site 4
S35
P
V
S
R
R
P
G
S
A
A
T
T
K
P
I
Site 5
T39
R
P
G
S
A
A
T
T
K
P
I
V
R
S
V
Site 6
S45
T
T
K
P
I
V
R
S
V
S
V
V
T
G
S
Site 7
S47
K
P
I
V
R
S
V
S
V
V
T
G
S
E
Q
Site 8
S76
A
I
N
N
L
R
R
S
N
S
T
T
Q
V
S
Site 9
S78
N
N
L
R
R
S
N
S
T
T
Q
V
S
Q
P
Site 10
T79
N
L
R
R
S
N
S
T
T
Q
V
S
Q
P
R
Site 11
T80
L
R
R
S
N
S
T
T
Q
V
S
Q
P
R
S
Site 12
S83
S
N
S
T
T
Q
V
S
Q
P
R
S
G
S
P
Site 13
S87
T
Q
V
S
Q
P
R
S
G
S
P
R
P
T
E
Site 14
S89
V
S
Q
P
R
S
G
S
P
R
P
T
E
P
T
Site 15
T93
R
S
G
S
P
R
P
T
E
P
T
D
F
L
M
Site 16
T96
S
P
R
P
T
E
P
T
D
F
L
M
L
F
E
Site 17
S105
F
L
M
L
F
E
G
S
P
S
G
K
K
R
P
Site 18
S107
M
L
F
E
G
S
P
S
G
K
K
R
P
A
S
Site 19
S114
S
G
K
K
R
P
A
S
L
S
T
A
P
S
E
Site 20
S116
K
K
R
P
A
S
L
S
T
A
P
S
E
K
G
Site 21
S120
A
S
L
S
T
A
P
S
E
K
G
A
T
W
N
Site 22
T125
A
P
S
E
K
G
A
T
W
N
V
L
D
D
Q
Site 23
T137
D
D
Q
P
R
G
F
T
L
P
S
N
A
R
S
Site 24
S140
P
R
G
F
T
L
P
S
N
A
R
S
S
S
A
Site 25
S144
T
L
P
S
N
A
R
S
S
S
A
L
D
S
P
Site 26
S145
L
P
S
N
A
R
S
S
S
A
L
D
S
P
A
Site 27
S146
P
S
N
A
R
S
S
S
A
L
D
S
P
A
G
Site 28
S150
R
S
S
S
A
L
D
S
P
A
G
P
R
R
K
Site 29
T160
G
P
R
R
K
E
C
T
V
A
L
A
P
N
F
Site 30
T191
T
M
V
H
N
R
Y
T
P
S
E
R
A
P
P
Site 31
S193
V
H
N
R
Y
T
P
S
E
R
A
P
P
L
K
Site 32
S202
R
A
P
P
L
K
S
S
N
Q
T
A
P
S
L
Site 33
T205
P
L
K
S
S
N
Q
T
A
P
S
L
N
N
I
Site 34
S208
S
S
N
Q
T
A
P
S
L
N
N
I
I
K
A
Site 35
T217
N
N
I
I
K
A
A
T
C
E
G
S
E
S
S
Site 36
S221
K
A
A
T
C
E
G
S
E
S
S
G
F
G
K
Site 37
S223
A
T
C
E
G
S
E
S
S
G
F
G
K
L
P
Site 38
S224
T
C
E
G
S
E
S
S
G
F
G
K
L
P
K
Site 39
S234
G
K
L
P
K
N
V
S
S
A
T
H
S
A
R
Site 40
S235
K
L
P
K
N
V
S
S
A
T
H
S
A
R
N
Site 41
S239
N
V
S
S
A
T
H
S
A
R
N
N
T
G
G
Site 42
T244
T
H
S
A
R
N
N
T
G
G
S
T
G
L
P
Site 43
T257
L
P
R
R
K
E
V
T
E
E
E
A
E
R
F
Site 44
Y279
A
V
T
I
Q
R
W
Y
R
H
Q
V
Q
R
R
Site 45
S308
R
E
E
Q
R
Q
R
S
G
E
G
T
L
L
D
Site 46
T312
R
Q
R
S
G
E
G
T
L
L
D
L
H
Q
Q
Site 47
S355
A
L
R
A
Q
K
A
S
T
A
E
R
G
P
P
Site 48
T368
P
P
E
N
P
R
E
T
R
V
P
G
M
R
Q
Site 49
S381
R
Q
P
A
Q
E
L
S
P
T
P
G
G
T
A
Site 50
T383
P
A
Q
E
L
S
P
T
P
G
G
T
A
H
Q
Site 51
T413
P
G
D
R
C
L
P
T
S
D
S
S
P
E
P
Site 52
S414
G
D
R
C
L
P
T
S
D
S
S
P
E
P
Q
Site 53
S416
R
C
L
P
T
S
D
S
S
P
E
P
Q
Q
P
Site 54
S417
C
L
P
T
S
D
S
S
P
E
P
Q
Q
P
P
Site 55
T428
Q
Q
P
P
E
D
R
T
Q
D
V
L
A
Q
D
Site 56
S450
M
M
A
P
S
R
G
S
A
K
S
R
G
P
L
Site 57
S453
P
S
R
G
S
A
K
S
R
G
P
L
E
E
L
Site 58
T463
P
L
E
E
L
L
H
T
L
Q
L
L
E
K
E
Site 59
T479
D
A
L
P
R
P
R
T
H
H
R
G
R
Y
A
Site 60
Y485
R
T
H
H
R
G
R
Y
A
W
A
S
E
V
T
Site 61
S489
R
G
R
Y
A
W
A
S
E
V
T
T
E
D
D
Site 62
T493
A
W
A
S
E
V
T
T
E
D
D
A
S
S
L
Site 63
S498
V
T
T
E
D
D
A
S
S
L
T
A
D
N
L
Site 64
S499
T
T
E
D
D
A
S
S
L
T
A
D
N
L
E
Site 65
T501
E
D
D
A
S
S
L
T
A
D
N
L
E
K
F
Site 66
S512
L
E
K
F
G
K
L
S
A
F
P
E
P
P
E
Site 67
T522
P
E
P
P
E
D
G
T
L
L
S
E
A
K
L
Site 68
S525
P
E
D
G
T
L
L
S
E
A
K
L
Q
S
I
Site 69
S531
L
S
E
A
K
L
Q
S
I
M
S
F
L
D
E
Site 70
S534
A
K
L
Q
S
I
M
S
F
L
D
E
M
E
K
Site 71
S542
F
L
D
E
M
E
K
S
G
Q
D
Q
L
D
S
Site 72
S549
S
G
Q
D
Q
L
D
S
Q
Q
E
G
W
V
P
Site 73
S570
L
E
L
G
S
E
V
S
T
S
V
M
R
L
K
Site 74
T571
E
L
G
S
E
V
S
T
S
V
M
R
L
K
L
Site 75
S572
L
G
S
E
V
S
T
S
V
M
R
L
K
L
E
Site 76
T601
L
A
Q
Q
R
D
L
T
A
R
R
V
K
E
T
Site 77
T608
T
A
R
R
V
K
E
T
E
K
A
L
S
R
Q
Site 78
Y623
L
Q
R
Q
R
E
H
Y
E
A
T
I
Q
R
H
Site 79
T663
K
Q
E
D
Q
R
C
T
E
R
V
A
Q
A
Q
Site 80
S685
K
K
L
K
E
L
M
S
A
T
E
K
A
R
R
Site 81
S697
A
R
R
E
K
W
I
S
E
K
T
K
K
I
K
Site 82
T707
T
K
K
I
K
E
V
T
V
R
G
L
E
P
E
Site 83
S731
Q
E
V
R
R
L
K
S
L
H
E
A
E
L
L
Site 84
S740
H
E
A
E
L
L
Q
S
D
E
R
A
S
Q
R
Site 85
S745
L
Q
S
D
E
R
A
S
Q
R
C
L
R
Q
A
Site 86
Y797
Q
Q
Q
R
Q
R
L
Y
S
E
V
A
E
E
R
Site 87
S798
Q
Q
R
Q
R
L
Y
S
E
V
A
E
E
R
E
Site 88
S830
Q
Q
L
E
E
S
S
S
A
L
T
R
A
L
R
Site 89
T833
E
E
S
S
S
A
L
T
R
A
L
R
A
E
F
Site 90
Y933
I
K
R
L
R
D
K
Y
E
A
E
L
S
E
L
Site 91
S938
D
K
Y
E
A
E
L
S
E
L
E
Q
S
E
R
Site 92
S943
E
L
S
E
L
E
Q
S
E
R
K
L
Q
E
R
Site 93
S952
R
K
L
Q
E
R
C
S
E
L
K
G
Q
L
G
Site 94
S991
A
V
N
E
Q
L
S
S
E
R
S
N
L
A
Q
Site 95
S994
E
Q
L
S
S
E
R
S
N
L
A
Q
V
I
R
Site 96
T1024
Q
A
K
A
E
L
A
T
L
Q
A
R
Q
Q
L
Site 97
T1042
E
V
H
R
R
V
K
T
A
L
A
R
K
E
E
Site 98
S1052
A
R
K
E
E
A
V
S
S
L
R
T
Q
H
E
Site 99
S1053
R
K
E
E
A
V
S
S
L
R
T
Q
H
E
A
Site 100
T1079
L
E
Q
H
R
R
P
T
P
S
T
K
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation