PhosphoNET

           
Protein Info 
   
Short Name:  TFR2
Full Name:  Transferrin receptor protein 2
Alias:  HFE3; Tfr2; TFRC2; Transferrin receptor 2
Type:  Receptor, misc.; Membrane protein, integral
Mass (Da):  88737
Number AA:  801
UniProt ID:  Q9UP52
International Prot ID:  IPI00219900
Sequence:  Retrieve full protein sequence
   
GO Terms  External Links Internal Links  
   
Cellular Component:  GO:0005737  GO:0005887   Uniprot OncoNet
Molecular Function:  GO:0008233  GO:0004998   PhosphoSite+ KinaseNET
Biological Process:  GO:0006879  GO:0006826  GO:0006508 Phosida TranscriptoNet
    STRING Kinexus Products
   
Info Box  A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites 
-7-6-5-4-3-2-101234567Expt. conf.EffectKinasePPaseKinexus ProductsRef.Evol.Kinase Pred.P-site Match
Site 1S15FQRAQQLSPRSSQTV
Site 2S19QQLSPRSSQTVYQRV
Site 3T21LSPRSSQTVYQRVEG
Site 4Y23PRSSQTVYQRVEGPR
Site 5T47DGEEGAETLAHFCPM
Site 6S64RGPEPLGSRPRQPNL
Site 7T341GFPSFNQTQFPPVAS
Site 8Y389GSLLGSPYHLGPGPR
Site 9S443WGPGAAKSAVGTAIL
 
Legend 
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available  
Products available
 


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