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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SNX6
Full Name:
Sorting nexin-6
Alias:
Sorting nexin 6; TFAF2; TRAF4-associated factor 2
Type:
Transport protein, facilitator
Mass (Da):
46649
Number AA:
406
UniProt ID:
Q9UNH7
International Prot ID:
IPI00298111
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005622
GO:0005737
GO:0044424
Uniprot
OncoNet
Molecular Function:
GO:0005488
GO:0005515
GO:0005543
PhosphoSite+
KinaseNET
Biological Process:
GO:0006469
GO:0006810
GO:0006886
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S13
D
D
G
P
D
F
L
S
E
E
D
R
G
L
K
Site 2
S37
A
A
L
Q
V
D
I
S
D
A
L
S
E
R
D
Site 3
S41
V
D
I
S
D
A
L
S
E
R
D
K
V
K
F
Site 4
T49
E
R
D
K
V
K
F
T
V
H
T
K
S
S
L
Site 5
S54
K
F
T
V
H
T
K
S
S
L
P
N
F
K
Q
Site 6
S55
F
T
V
H
T
K
S
S
L
P
N
F
K
Q
N
Site 7
S65
N
F
K
Q
N
E
F
S
V
V
R
Q
H
E
E
Site 8
Y86
S
F
V
E
N
E
D
Y
A
G
Y
I
I
P
P
Site 9
Y89
E
N
E
D
Y
A
G
Y
I
I
P
P
A
P
P
Site 10
S103
P
R
P
D
F
D
A
S
R
E
K
L
Q
K
L
Site 11
S116
K
L
G
E
G
E
G
S
M
T
K
E
E
F
T
Site 12
T118
G
E
G
E
G
S
M
T
K
E
E
F
T
K
M
Site 13
Y133
K
Q
E
L
E
A
E
Y
L
A
I
F
K
K
T
Site 14
Y169
N
F
H
V
F
L
E
Y
N
Q
D
L
S
V
R
Site 15
S174
L
E
Y
N
Q
D
L
S
V
R
G
K
N
K
K
Site 16
T215
D
F
F
E
H
E
R
T
F
L
L
E
Y
H
N
Site 17
Y220
E
R
T
F
L
L
E
Y
H
N
R
V
K
D
A
Site 18
S228
H
N
R
V
K
D
A
S
A
K
S
D
R
M
T
Site 19
S231
V
K
D
A
S
A
K
S
D
R
M
T
R
S
H
Site 20
T235
S
A
K
S
D
R
M
T
R
S
H
K
S
A
A
Site 21
S240
R
M
T
R
S
H
K
S
A
A
D
D
Y
N
R
Site 22
Y245
H
K
S
A
A
D
D
Y
N
R
I
G
S
S
L
Site 23
S250
D
D
Y
N
R
I
G
S
S
L
Y
A
L
G
T
Site 24
S251
D
Y
N
R
I
G
S
S
L
Y
A
L
G
T
Q
Site 25
Y253
N
R
I
G
S
S
L
Y
A
L
G
T
Q
D
S
Site 26
T257
S
S
L
Y
A
L
G
T
Q
D
S
T
D
I
C
Site 27
T277
V
S
E
L
F
D
K
T
R
K
I
E
A
R
V
Site 28
S285
R
K
I
E
A
R
V
S
A
D
E
D
L
K
L
Site 29
S293
A
D
E
D
L
K
L
S
D
L
L
K
Y
Y
L
Site 30
Y298
K
L
S
D
L
L
K
Y
Y
L
R
E
S
Q
A
Site 31
Y299
L
S
D
L
L
K
Y
Y
L
R
E
S
Q
A
A
Site 32
S303
L
K
Y
Y
L
R
E
S
Q
A
A
K
D
L
L
Site 33
Y311
Q
A
A
K
D
L
L
Y
R
R
S
R
S
L
V
Site 34
S314
K
D
L
L
Y
R
R
S
R
S
L
V
D
Y
E
Site 35
S316
L
L
Y
R
R
S
R
S
L
V
D
Y
E
N
A
Site 36
Y320
R
S
R
S
L
V
D
Y
E
N
A
N
K
A
L
Site 37
S343
D
V
L
Q
A
E
T
S
Q
Q
L
C
C
Q
K
Site 38
S357
K
F
E
K
I
S
E
S
A
K
Q
E
L
I
D
Site 39
T367
Q
E
L
I
D
F
K
T
R
R
V
A
A
F
R
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation