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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CDC14A
Full Name:
Alias:
CDC14 cell division cycle 14 homolog A
Type:
Mass (Da):
66574
Number AA:
594
UniProt ID:
Q9UNH5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
Y20
E
F
M
K
D
R
L
Y
F
A
T
L
R
N
R
Site 2
T23
K
D
R
L
Y
F
A
T
L
R
N
R
P
K
S
Site 3
S30
T
L
R
N
R
P
K
S
T
V
N
T
H
Y
F
Site 4
T34
R
P
K
S
T
V
N
T
H
Y
F
S
I
D
E
Site 5
Y36
K
S
T
V
N
T
H
Y
F
S
I
D
E
E
L
Site 6
S38
T
V
N
T
H
Y
F
S
I
D
E
E
L
V
Y
Site 7
Y45
S
I
D
E
E
L
V
Y
E
N
F
Y
A
D
F
Site 8
Y49
E
L
V
Y
E
N
F
Y
A
D
F
G
P
L
N
Site 9
S73
K
L
N
K
K
L
K
S
Y
S
L
S
R
K
K
Site 10
S75
N
K
K
L
K
S
Y
S
L
S
R
K
K
I
V
Site 11
S77
K
L
K
S
Y
S
L
S
R
K
K
I
V
H
Y
Site 12
Y84
S
R
K
K
I
V
H
Y
T
C
F
D
Q
R
K
Site 13
Y106
I
G
A
Y
A
V
I
Y
L
K
K
T
P
E
E
Site 14
T110
A
V
I
Y
L
K
K
T
P
E
E
A
Y
R
A
Site 15
S120
E
A
Y
R
A
L
L
S
G
S
N
P
P
Y
L
Site 16
S122
Y
R
A
L
L
S
G
S
N
P
P
Y
L
P
F
Site 17
Y126
L
S
G
S
N
P
P
Y
L
P
F
R
D
A
S
Site 18
Y169
E
T
F
D
V
D
E
Y
E
H
Y
E
R
V
E
Site 19
Y172
D
V
D
E
Y
E
H
Y
E
R
V
E
N
G
D
Site 20
S192
P
G
K
F
L
A
F
S
G
P
H
P
K
S
K
Site 21
S198
F
S
G
P
H
P
K
S
K
I
E
N
G
Y
P
Site 22
Y204
K
S
K
I
E
N
G
Y
P
L
H
A
P
E
A
Site 23
Y212
P
L
H
A
P
E
A
Y
F
P
Y
F
K
K
H
Site 24
Y215
A
P
E
A
Y
F
P
Y
F
K
K
H
N
V
T
Site 25
Y232
V
R
L
N
K
K
I
Y
E
A
K
R
F
T
D
Site 26
T238
I
Y
E
A
K
R
F
T
D
A
G
F
E
H
Y
Site 27
Y245
T
D
A
G
F
E
H
Y
D
L
F
F
I
D
G
Site 28
S256
F
I
D
G
S
T
P
S
D
N
I
V
R
R
F
Site 29
S315
I
R
I
C
R
P
G
S
I
I
G
P
Q
Q
H
Site 30
S330
F
L
E
E
K
Q
A
S
L
W
V
Q
G
D
I
Site 31
S340
V
Q
G
D
I
F
R
S
K
L
K
N
R
P
S
Site 32
S347
S
K
L
K
N
R
P
S
S
E
G
S
I
N
K
Site 33
S348
K
L
K
N
R
P
S
S
E
G
S
I
N
K
I
Site 34
S351
N
R
P
S
S
E
G
S
I
N
K
I
L
S
G
Site 35
S363
L
S
G
L
D
D
M
S
I
G
G
N
L
S
K
Site 36
S369
M
S
I
G
G
N
L
S
K
T
Q
N
M
E
R
Site 37
T371
I
G
G
N
L
S
K
T
Q
N
M
E
R
F
G
Site 38
S404
D
K
L
R
A
L
K
S
Q
R
Q
P
R
T
S
Site 39
T410
K
S
Q
R
Q
P
R
T
S
P
S
C
A
F
R
Site 40
S411
S
Q
R
Q
P
R
T
S
P
S
C
A
F
R
S
Site 41
S413
R
Q
P
R
T
S
P
S
C
A
F
R
S
D
D
Site 42
S418
S
P
S
C
A
F
R
S
D
D
T
K
G
H
P
Site 43
T421
C
A
F
R
S
D
D
T
K
G
H
P
R
A
V
Site 44
S429
K
G
H
P
R
A
V
S
Q
P
F
R
L
S
S
Site 45
S435
V
S
Q
P
F
R
L
S
S
S
L
Q
G
S
A
Site 46
S436
S
Q
P
F
R
L
S
S
S
L
Q
G
S
A
V
Site 47
S437
Q
P
F
R
L
S
S
S
L
Q
G
S
A
V
T
Site 48
S441
L
S
S
S
L
Q
G
S
A
V
T
L
K
T
S
Site 49
T444
S
L
Q
G
S
A
V
T
L
K
T
S
K
M
A
Site 50
T447
G
S
A
V
T
L
K
T
S
K
M
A
L
S
P
Site 51
S453
K
T
S
K
M
A
L
S
P
S
A
T
A
K
R
Site 52
S455
S
K
M
A
L
S
P
S
A
T
A
K
R
I
N
Site 53
T457
M
A
L
S
P
S
A
T
A
K
R
I
N
R
T
Site 54
S465
A
K
R
I
N
R
T
S
L
S
S
G
A
T
V
Site 55
S467
R
I
N
R
T
S
L
S
S
G
A
T
V
R
S
Site 56
S468
I
N
R
T
S
L
S
S
G
A
T
V
R
S
F
Site 57
T471
T
S
L
S
S
G
A
T
V
R
S
F
S
I
N
Site 58
S474
S
S
G
A
T
V
R
S
F
S
I
N
S
R
L
Site 59
S476
G
A
T
V
R
S
F
S
I
N
S
R
L
A
S
Site 60
S479
V
R
S
F
S
I
N
S
R
L
A
S
S
L
G
Site 61
S483
S
I
N
S
R
L
A
S
S
L
G
N
L
N
A
Site 62
T492
L
G
N
L
N
A
A
T
D
D
P
E
N
K
K
Site 63
T500
D
D
P
E
N
K
K
T
S
S
S
S
K
A
G
Site 64
S501
D
P
E
N
K
K
T
S
S
S
S
K
A
G
F
Site 65
S502
P
E
N
K
K
T
S
S
S
S
K
A
G
F
T
Site 66
S504
N
K
K
T
S
S
S
S
K
A
G
F
T
A
S
Site 67
T509
S
S
S
K
A
G
F
T
A
S
P
F
T
N
L
Site 68
S511
S
K
A
G
F
T
A
S
P
F
T
N
L
L
N
Site 69
S521
T
N
L
L
N
G
S
S
Q
P
T
T
R
N
Y
Site 70
T524
L
N
G
S
S
Q
P
T
T
R
N
Y
P
E
L
Site 71
T525
N
G
S
S
Q
P
T
T
R
N
Y
P
E
L
N
Site 72
Y528
S
Q
P
T
T
R
N
Y
P
E
L
N
N
N
Q
Site 73
Y536
P
E
L
N
N
N
Q
Y
N
R
S
S
N
S
N
Site 74
S539
N
N
N
Q
Y
N
R
S
S
N
S
N
G
G
N
Site 75
S540
N
N
Q
Y
N
R
S
S
N
S
N
G
G
N
L
Site 76
S549
S
N
G
G
N
L
N
S
P
P
G
P
H
S
A
Site 77
S555
N
S
P
P
G
P
H
S
A
K
T
E
E
H
T
Site 78
T558
P
G
P
H
S
A
K
T
E
E
H
T
T
I
L
Site 79
T563
A
K
T
E
E
H
T
T
I
L
R
P
S
Y
T
Site 80
S568
H
T
T
I
L
R
P
S
Y
T
G
L
S
S
S
Site 81
Y569
T
T
I
L
R
P
S
Y
T
G
L
S
S
S
S
Site 82
T570
T
I
L
R
P
S
Y
T
G
L
S
S
S
S
A
Site 83
S573
R
P
S
Y
T
G
L
S
S
S
S
A
R
F
L
Site 84
S574
P
S
Y
T
G
L
S
S
S
S
A
R
F
L
S
Site 85
S575
S
Y
T
G
L
S
S
S
S
A
R
F
L
S
R
Site 86
S576
Y
T
G
L
S
S
S
S
A
R
F
L
S
R
S
Site 87
S581
S
S
S
A
R
F
L
S
R
S
I
P
S
L
Q
Site 88
S583
S
A
R
F
L
S
R
S
I
P
S
L
Q
S
E
Site 89
S586
F
L
S
R
S
I
P
S
L
Q
S
E
Y
V
H
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation