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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
EDAR
Full Name:
Tumor necrosis factor receptor superfamily member EDAR precursor
Alias:
Anhidrotic ectodysplasin receptor 1;Downless homolog;EDA-A1 receptor;Ectodermal dysplasia receptor;Ectodysplasin-A receptor
Type:
Receptor
Mass (Da):
48582
Number AA:
448
UniProt ID:
Q9UNE0
International Prot ID:
IPI00007051
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
GO:0005886
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0004888
PhosphoSite+
KinaseNET
Biological Process:
GO:0006915
GO:0030154
GO:0008544
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S153
K
E
C
V
G
A
T
S
G
A
S
A
N
F
P
Site 2
S216
Y
I
L
K
T
K
P
S
A
P
A
C
C
T
S
Site 3
T222
P
S
A
P
A
C
C
T
S
H
P
G
K
S
V
Site 4
S223
S
A
P
A
C
C
T
S
H
P
G
K
S
V
E
Site 5
S228
C
T
S
H
P
G
K
S
V
E
A
Q
V
S
K
Site 6
S234
K
S
V
E
A
Q
V
S
K
D
E
E
K
K
E
Site 7
T259
K
D
E
F
E
K
L
T
A
T
P
A
K
P
T
Site 8
T261
E
F
E
K
L
T
A
T
P
A
K
P
T
K
S
Site 9
S268
T
P
A
K
P
T
K
S
E
N
D
A
S
S
E
Site 10
S273
T
K
S
E
N
D
A
S
S
E
N
E
Q
L
L
Site 11
S274
K
S
E
N
D
A
S
S
E
N
E
Q
L
L
S
Site 12
S281
S
E
N
E
Q
L
L
S
R
S
V
D
S
D
E
Site 13
S283
N
E
Q
L
L
S
R
S
V
D
S
D
E
E
P
Site 14
S286
L
L
S
R
S
V
D
S
D
E
E
P
A
P
D
Site 15
S297
P
A
P
D
K
Q
G
S
P
E
L
C
L
L
S
Site 16
S313
V
H
L
A
R
E
K
S
A
T
S
N
K
S
A
Site 17
T315
L
A
R
E
K
S
A
T
S
N
K
S
A
G
I
Site 18
S316
A
R
E
K
S
A
T
S
N
K
S
A
G
I
Q
Site 19
S319
K
S
A
T
S
N
K
S
A
G
I
Q
S
R
R
Site 20
S324
N
K
S
A
G
I
Q
S
R
R
K
K
I
L
D
Site 21
T356
P
F
D
C
L
E
K
T
S
R
M
L
S
S
T
Site 22
S357
F
D
C
L
E
K
T
S
R
M
L
S
S
T
Y
Site 23
S361
E
K
T
S
R
M
L
S
S
T
Y
N
S
E
K
Site 24
S362
K
T
S
R
M
L
S
S
T
Y
N
S
E
K
A
Site 25
T363
T
S
R
M
L
S
S
T
Y
N
S
E
K
A
V
Site 26
Y364
S
R
M
L
S
S
T
Y
N
S
E
K
A
V
V
Site 27
S366
M
L
S
S
T
Y
N
S
E
K
A
V
V
K
T
Site 28
T373
S
E
K
A
V
V
K
T
W
R
H
L
A
E
S
Site 29
S380
T
W
R
H
L
A
E
S
F
G
L
K
R
D
E
Site 30
T403
Q
L
F
D
R
I
S
T
A
G
Y
S
I
P
E
Site 31
Y406
D
R
I
S
T
A
G
Y
S
I
P
E
L
L
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation