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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SCML1
Full Name:
Sex comb on midleg-like protein 1
Alias:
sex comb on midleg-like 1
Type:
Mass (Da):
37450
Number AA:
208
UniProt ID:
Q9UN30
International Prot ID:
IPI00186157
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003700
PhosphoSite+
KinaseNET
Biological Process:
GO:0009653
GO:0045449
GO:0006350
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
M
S
N
S
S
S
E
I
D
V
I
K
T
Site 2
T14
S
E
I
D
V
I
K
T
R
I
P
T
Y
D
E
Site 3
T18
V
I
K
T
R
I
P
T
Y
D
E
D
D
N
T
Site 4
Y19
I
K
T
R
I
P
T
Y
D
E
D
D
N
T
I
Site 5
T25
T
Y
D
E
D
D
N
T
I
L
Y
A
Y
E
T
Site 6
Y28
E
D
D
N
T
I
L
Y
A
Y
E
T
K
P
E
Site 7
T57
N
T
E
E
Q
L
K
T
V
D
D
V
L
I
H
Site 8
S87
D
V
I
R
R
K
V
S
K
I
Q
R
F
H
A
Site 9
Y104
L
W
T
N
H
K
R
Y
G
Y
K
K
H
S
Y
Site 10
Y106
T
N
H
K
R
Y
G
Y
K
K
H
S
Y
R
L
Site 11
S110
R
Y
G
Y
K
K
H
S
Y
R
L
V
K
K
L
Site 12
Y111
Y
G
Y
K
K
H
S
Y
R
L
V
K
K
L
K
Site 13
Y128
K
M
K
K
N
E
V
Y
E
T
F
S
Y
P
E
Site 14
T130
K
K
N
E
V
Y
E
T
F
S
Y
P
E
S
Y
Site 15
S132
N
E
V
Y
E
T
F
S
Y
P
E
S
Y
S
P
Site 16
Y133
E
V
Y
E
T
F
S
Y
P
E
S
Y
S
P
T
Site 17
S136
E
T
F
S
Y
P
E
S
Y
S
P
T
L
P
V
Site 18
S138
F
S
Y
P
E
S
Y
S
P
T
L
P
V
S
R
Site 19
T140
Y
P
E
S
Y
S
P
T
L
P
V
S
R
R
E
Site 20
S144
Y
S
P
T
L
P
V
S
R
R
E
N
N
S
P
Site 21
S150
V
S
R
R
E
N
N
S
P
S
N
L
P
R
P
Site 22
S152
R
R
E
N
N
S
P
S
N
L
P
R
P
S
F
Site 23
S158
P
S
N
L
P
R
P
S
F
C
M
E
E
Y
Q
Site 24
Y164
P
S
F
C
M
E
E
Y
Q
R
A
E
L
E
E
Site 25
S176
L
E
E
D
P
I
L
S
R
T
P
S
P
V
H
Site 26
T178
E
D
P
I
L
S
R
T
P
S
P
V
H
P
S
Site 27
S180
P
I
L
S
R
T
P
S
P
V
H
P
S
D
F
Site 28
S185
T
P
S
P
V
H
P
S
D
F
S
E
H
N
C
Site 29
Y195
S
E
H
N
C
Q
P
Y
Y
A
S
D
G
A
T
Site 30
Y196
E
H
N
C
Q
P
Y
Y
A
S
D
G
A
T
Y
Site 31
S198
N
C
Q
P
Y
Y
A
S
D
G
A
T
Y
G
S
Site 32
T202
Y
Y
A
S
D
G
A
T
Y
G
S
S
S
G
L
Site 33
Y203
Y
A
S
D
G
A
T
Y
G
S
S
S
G
L
C
Site 34
S205
S
D
G
A
T
Y
G
S
S
S
G
L
C
L
G
Site 35
S206
D
G
A
T
Y
G
S
S
S
G
L
C
L
G
N
Site 36
S207
G
A
T
Y
G
S
S
S
G
L
C
L
G
N
P
Site 37
S218
L
G
N
P
R
A
D
S
I
H
N
T
Y
S
T
Site 38
T222
R
A
D
S
I
H
N
T
Y
S
T
D
H
A
S
Site 39
S224
D
S
I
H
N
T
Y
S
T
D
H
A
S
A
A
Site 40
T225
S
I
H
N
T
Y
S
T
D
H
A
S
A
A
P
Site 41
S229
T
Y
S
T
D
H
A
S
A
A
P
P
S
V
T
Site 42
S234
H
A
S
A
A
P
P
S
V
T
R
S
P
V
E
Site 43
S238
A
P
P
S
V
T
R
S
P
V
E
N
D
G
Y
Site 44
Y245
S
P
V
E
N
D
G
Y
I
E
E
G
S
I
T
Site 45
T252
Y
I
E
E
G
S
I
T
K
H
P
S
T
W
S
Site 46
S256
G
S
I
T
K
H
P
S
T
W
S
V
E
A
V
Site 47
T257
S
I
T
K
H
P
S
T
W
S
V
E
A
V
V
Site 48
S259
T
K
H
P
S
T
W
S
V
E
A
V
V
L
F
Site 49
Y316
G
T
A
V
K
L
C
Y
Y
I
D
R
L
K
Q
Site 50
Y317
T
A
V
K
L
C
Y
Y
I
D
R
L
K
Q
G
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation