KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
PTPRQ
Full Name:
Receptor-type tyrosine-protein phosphatase Q
Alias:
EC 3.1.3.48
Type:
Protein-tyrosine phosphatase, receptor
Mass (Da):
260924
Number AA:
2332
UniProt ID:
Q9UMZ3
International Prot ID:
not found
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016021
Uniprot
OncoNet
Molecular Function:
GO:0004725
GO:0004872
PhosphoSite+
KinaseNET
Biological Process:
GO:0006470
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S20
K
L
R
A
F
N
I
S
T
H
S
F
S
L
H
Site 2
T21
L
R
A
F
N
I
S
T
H
S
F
S
L
H
W
Site 3
S25
N
I
S
T
H
S
F
S
L
H
W
S
L
P
S
Site 4
S29
H
S
F
S
L
H
W
S
L
P
S
G
H
V
E
Site 5
S85
S
I
S
T
T
Y
T
S
P
V
T
R
I
V
T
Site 6
S111
L
A
G
E
R
V
G
S
A
G
I
L
L
S
W
Site 7
S117
G
S
A
G
I
L
L
S
W
N
T
P
P
N
P
Site 8
T120
G
I
L
L
S
W
N
T
P
P
N
P
N
G
R
Site 9
S239
I
S
V
K
H
A
R
S
G
I
V
V
K
D
V
Site 10
S363
T
G
N
I
T
G
K
S
F
S
I
L
W
D
P
Site 11
T849
S
N
G
N
E
E
R
T
I
N
T
T
S
L
T
Site 12
S1370
V
G
N
G
N
Q
F
S
N
V
V
K
F
T
T
Site 13
Y1415
A
N
G
I
I
T
Q
Y
M
V
T
V
E
R
N
Site 14
S1619
C
Y
L
I
D
V
K
S
V
D
N
D
E
F
N
Site 15
T1953
V
E
I
I
L
S
V
T
L
C
I
L
S
I
I
Site 16
Y1982
K
Q
K
E
G
G
T
Y
S
P
Q
D
A
E
I
Site 17
S1983
Q
K
E
G
G
T
Y
S
P
Q
D
A
E
I
I
Site 18
T1992
Q
D
A
E
I
I
D
T
K
L
K
L
D
Q
L
Site 19
T2001
L
K
L
D
Q
L
I
T
V
A
D
L
E
L
K
Site 20
T2013
E
L
K
D
E
R
L
T
R
P
I
S
K
K
S
Site 21
S2017
E
R
L
T
R
P
I
S
K
K
S
F
L
Q
H
Site 22
S2020
T
R
P
I
S
K
K
S
F
L
Q
H
V
E
E
Site 23
S2051
P
K
F
L
Q
D
L
S
S
T
D
A
D
L
P
Site 24
S2052
K
F
L
Q
D
L
S
S
T
D
A
D
L
P
W
Site 25
Y2072
R
F
P
N
I
K
P
Y
N
N
N
R
V
K
L
Site 26
S2088
A
D
A
S
V
P
G
S
D
Y
I
N
A
S
Y
Site 27
Y2090
A
S
V
P
G
S
D
Y
I
N
A
S
Y
I
S
Site 28
Y2095
S
D
Y
I
N
A
S
Y
I
S
G
Y
L
C
P
Site 29
T2108
C
P
N
E
F
I
A
T
Q
G
P
L
P
G
T
Site 30
T2115
T
Q
G
P
L
P
G
T
V
G
D
F
W
R
M
Site 31
T2135
A
K
T
L
V
M
L
T
Q
C
F
E
K
G
R
Site 32
T2176
E
D
V
Q
I
D
W
T
I
R
D
L
K
I
E
Site 33
S2221
F
V
K
L
V
R
A
S
R
A
H
D
T
T
P
Site 34
T2226
R
A
S
R
A
H
D
T
T
P
M
I
V
H
C
Site 35
T2227
A
S
R
A
H
D
T
T
P
M
I
V
H
C
S
Site 36
S2294
Q
C
I
L
D
L
L
S
N
K
G
S
N
Q
P
Site 37
S2298
D
L
L
S
N
K
G
S
N
Q
P
I
C
F
V
Site 38
S2315
S
A
L
Q
K
M
D
S
L
D
A
M
E
G
D
Site 39
T2330
V
E
L
E
W
E
E
T
T
M
_
_
_
_
_
Site 40
T2331
E
L
E
W
E
E
T
T
M
_
_
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation