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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
SUFU
Full Name:
Suppressor of fused homolog
Alias:
PRO1280; SUFUH; SUFUXL; suppressor of fused; suppressor of fused homolog (Drosophila)
Type:
Adaptor/scaffold; Transcription, coactivator/corepressor
Mass (Da):
53947
Number AA:
484
UniProt ID:
Q9UMX1
International Prot ID:
IPI00099179
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005737
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0042802
GO:0004871
GO:0003714
PhosphoSite+
KinaseNET
Biological Process:
GO:0006508
GO:0006355
GO:0007165
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S7
_
M
A
E
L
R
P
S
G
A
P
G
P
T
A
Site 2
T13
P
S
G
A
P
G
P
T
A
P
P
A
P
G
P
Site 3
Y38
P
P
G
L
H
A
I
Y
G
E
C
R
R
L
Y
Site 4
Y45
Y
G
E
C
R
R
L
Y
P
D
Q
P
N
P
L
Site 5
Y60
Q
V
T
A
I
V
K
Y
W
L
G
G
P
D
P
Site 6
Y70
G
G
P
D
P
L
D
Y
V
S
M
Y
R
N
V
Site 7
S72
P
D
P
L
D
Y
V
S
M
Y
R
N
V
G
S
Site 8
Y74
P
L
D
Y
V
S
M
Y
R
N
V
G
S
P
S
Site 9
S79
S
M
Y
R
N
V
G
S
P
S
A
N
I
P
E
Site 10
Y90
N
I
P
E
H
W
H
Y
I
S
F
G
L
S
D
Site 11
S96
H
Y
I
S
F
G
L
S
D
L
Y
G
D
N
R
Site 12
Y99
S
F
G
L
S
D
L
Y
G
D
N
R
V
H
E
Site 13
T108
D
N
R
V
H
E
F
T
G
T
D
G
P
S
G
Site 14
T110
R
V
H
E
F
T
G
T
D
G
P
S
G
F
G
Site 15
S114
F
T
G
T
D
G
P
S
G
F
G
F
E
L
T
Site 16
T121
S
G
F
G
F
E
L
T
F
R
L
K
R
E
T
Site 17
T128
T
F
R
L
K
R
E
T
G
E
S
A
P
P
T
Site 18
S131
L
K
R
E
T
G
E
S
A
P
P
T
W
P
A
Site 19
T135
T
G
E
S
A
P
P
T
W
P
A
E
L
M
Q
Site 20
Y147
L
M
Q
G
L
A
R
Y
V
F
Q
S
E
N
T
Site 21
S151
L
A
R
Y
V
F
Q
S
E
N
T
F
C
S
G
Site 22
S165
G
D
H
V
S
W
H
S
P
L
D
N
S
E
S
Site 23
S172
S
P
L
D
N
S
E
S
R
I
Q
H
M
L
L
Site 24
T180
R
I
Q
H
M
L
L
T
E
D
P
Q
M
Q
P
Site 25
T236
A
G
G
P
W
L
I
T
D
M
R
R
G
E
T
Site 26
T243
T
D
M
R
R
G
E
T
I
F
E
I
D
P
H
Site 27
T261
R
V
D
K
G
I
E
T
D
G
S
N
L
S
G
Site 28
S264
K
G
I
E
T
D
G
S
N
L
S
G
V
S
A
Site 29
S267
E
T
D
G
S
N
L
S
G
V
S
A
K
C
A
Site 30
S279
K
C
A
W
D
D
L
S
R
P
P
E
D
D
E
Site 31
S288
P
P
E
D
D
E
D
S
R
S
I
C
I
G
T
Site 32
S290
E
D
D
E
D
S
R
S
I
C
I
G
T
Q
P
Site 33
T295
S
R
S
I
C
I
G
T
Q
P
R
R
L
S
G
Site 34
S301
G
T
Q
P
R
R
L
S
G
K
D
T
E
Q
I
Site 35
T305
R
R
L
S
G
K
D
T
E
Q
I
R
E
T
L
Site 36
T311
D
T
E
Q
I
R
E
T
L
R
R
G
L
E
I
Site 37
S320
R
R
G
L
E
I
N
S
K
P
V
L
P
P
I
Site 38
S342
L
A
H
D
R
A
P
S
R
K
D
S
L
E
S
Site 39
S346
R
A
P
S
R
K
D
S
L
E
S
D
S
S
T
Site 40
S349
S
R
K
D
S
L
E
S
D
S
S
T
A
I
I
Site 41
S351
K
D
S
L
E
S
D
S
S
T
A
I
I
P
H
Site 42
S352
D
S
L
E
S
D
S
S
T
A
I
I
P
H
E
Site 43
T353
S
L
E
S
D
S
S
T
A
I
I
P
H
E
L
Site 44
T363
I
P
H
E
L
I
R
T
R
Q
L
E
S
V
H
Site 45
T396
L
L
H
G
R
H
F
T
Y
K
S
I
T
G
D
Site 46
Y397
L
H
G
R
H
F
T
Y
K
S
I
T
G
D
M
Site 47
Y424
F
A
T
E
E
H
P
Y
A
A
H
G
P
W
L
Site 48
T451
L
E
D
L
E
D
L
T
S
P
E
E
F
K
L
Site 49
S452
E
D
L
E
D
L
T
S
P
E
E
F
K
L
P
Site 50
Y462
E
F
K
L
P
K
E
Y
S
W
P
E
K
K
L
Site 51
S463
F
K
L
P
K
E
Y
S
W
P
E
K
K
L
K
Site 52
S481
L
P
D
V
V
F
D
S
P
L
H
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation