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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PHTF1
Full Name:
Putative homeodomain transcription factor 1
Alias:
Type:
Mass (Da):
87252
Number AA:
762
UniProt ID:
Q9UMS5
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S10
S
N
E
R
D
A
I
S
W
Y
Q
K
K
I
G
Site 2
Y12
E
R
D
A
I
S
W
Y
Q
K
K
I
G
A
Y
Site 3
T31
W
E
K
S
I
E
Q
T
Q
I
K
G
L
K
N
Site 4
S59
D
V
D
L
I
R
G
S
T
F
A
K
A
K
P
Site 5
T60
V
D
L
I
R
G
S
T
F
A
K
A
K
P
E
Site 6
T71
A
K
P
E
I
P
W
T
S
L
T
R
K
G
L
Site 7
S72
K
P
E
I
P
W
T
S
L
T
R
K
G
L
V
Site 8
T148
V
H
C
Q
I
V
S
T
Q
I
T
R
P
S
G
Site 9
T151
Q
I
V
S
T
Q
I
T
R
P
S
G
N
N
G
Site 10
S154
S
T
Q
I
T
R
P
S
G
N
N
G
N
R
R
Site 11
T168
R
R
R
K
L
R
K
T
V
N
G
D
G
S
R
Site 12
S174
K
T
V
N
G
D
G
S
R
E
N
G
N
N
S
Site 13
S182
R
E
N
G
N
N
S
S
D
K
V
R
G
I
E
Site 14
T190
D
K
V
R
G
I
E
T
L
E
S
V
P
I
I
Site 15
S193
R
G
I
E
T
L
E
S
V
P
I
I
G
G
F
Site 16
S216
I
K
R
V
K
L
I
S
N
K
G
T
E
T
D
Site 17
T220
K
L
I
S
N
K
G
T
E
T
D
N
D
P
S
Site 18
S227
T
E
T
D
N
D
P
S
C
V
H
P
I
I
K
Site 19
S254
T
R
E
K
A
K
F
S
D
G
E
K
C
R
R
Site 20
S272
R
R
L
G
N
G
V
S
D
D
L
S
S
E
E
Site 21
S276
N
G
V
S
D
D
L
S
S
E
E
D
G
E
A
Site 22
S277
G
V
S
D
D
L
S
S
E
E
D
G
E
A
R
Site 23
S293
Q
M
I
L
L
R
R
S
V
E
G
A
S
S
D
Site 24
S298
R
R
S
V
E
G
A
S
S
D
N
G
C
E
V
Site 25
S299
R
S
V
E
G
A
S
S
D
N
G
C
E
V
K
Site 26
S310
C
E
V
K
N
R
K
S
I
L
S
R
H
L
N
Site 27
S313
K
N
R
K
S
I
L
S
R
H
L
N
S
Q
V
Site 28
S318
I
L
S
R
H
L
N
S
Q
V
K
K
T
T
T
Site 29
S334
W
C
H
I
V
R
D
S
D
S
L
A
E
S
E
Site 30
S336
H
I
V
R
D
S
D
S
L
A
E
S
E
F
E
Site 31
S340
D
S
D
S
L
A
E
S
E
F
E
S
A
A
F
Site 32
S344
L
A
E
S
E
F
E
S
A
A
F
S
Q
G
S
Site 33
S348
E
F
E
S
A
A
F
S
Q
G
S
R
S
G
V
Site 34
S351
S
A
A
F
S
Q
G
S
R
S
G
V
S
G
G
Site 35
S353
A
F
S
Q
G
S
R
S
G
V
S
G
G
S
R
Site 36
S356
Q
G
S
R
S
G
V
S
G
G
S
R
S
L
N
Site 37
S359
R
S
G
V
S
G
G
S
R
S
L
N
M
S
R
Site 38
S361
G
V
S
G
G
S
R
S
L
N
M
S
R
R
D
Site 39
S365
G
S
R
S
L
N
M
S
R
R
D
S
E
S
T
Site 40
S369
L
N
M
S
R
R
D
S
E
S
T
R
H
D
S
Site 41
S371
M
S
R
R
D
S
E
S
T
R
H
D
S
E
T
Site 42
T372
S
R
R
D
S
E
S
T
R
H
D
S
E
T
E
Site 43
S376
S
E
S
T
R
H
D
S
E
T
E
D
M
L
W
Site 44
T378
S
T
R
H
D
S
E
T
E
D
M
L
W
D
D
Site 45
S395
H
G
P
E
C
R
S
S
V
T
S
D
S
E
G
Site 46
S398
E
C
R
S
S
V
T
S
D
S
E
G
A
H
V
Site 47
S400
R
S
S
V
T
S
D
S
E
G
A
H
V
N
T
Site 48
T407
S
E
G
A
H
V
N
T
L
H
S
G
T
K
R
Site 49
S432
H
L
F
W
L
Q
N
S
S
P
S
S
D
R
V
Site 50
S433
L
F
W
L
Q
N
S
S
P
S
S
D
R
V
S
Site 51
S435
W
L
Q
N
S
S
P
S
S
D
R
V
S
A
I
Site 52
S436
L
Q
N
S
S
P
S
S
D
R
V
S
A
I
I
Site 53
S440
S
P
S
S
D
R
V
S
A
I
I
W
E
G
N
Site 54
S465
E
I
S
G
I
I
M
S
R
V
N
A
Y
Q
Q
Site 55
Y470
I
M
S
R
V
N
A
Y
Q
Q
G
V
G
Y
Q
Site 56
S501
H
R
L
F
R
E
K
S
L
D
Q
L
K
S
I
Site 57
S507
K
S
L
D
Q
L
K
S
I
S
A
E
E
I
L
Site 58
Y555
M
C
V
A
E
R
T
Y
K
Q
R
F
L
F
A
Site 59
T569
A
K
L
F
S
H
I
T
S
A
R
K
A
R
K
Site 60
S570
K
L
F
S
H
I
T
S
A
R
K
A
R
K
Y
Site 61
Y577
S
A
R
K
A
R
K
Y
E
I
P
H
F
R
L
Site 62
S595
E
N
I
K
I
W
L
S
L
R
S
Y
L
K
R
Site 63
Y599
I
W
L
S
L
R
S
Y
L
K
R
R
G
P
Q
Site 64
S608
K
R
R
G
P
Q
R
S
V
D
V
V
V
S
S
Site 65
T637
Q
V
L
Q
G
H
K
T
F
L
N
D
A
Y
N
Site 66
S666
L
R
L
A
S
L
G
S
E
T
N
K
K
Y
S
Site 67
T668
L
A
S
L
G
S
E
T
N
K
K
Y
S
N
V
Site 68
Y672
G
S
E
T
N
K
K
Y
S
N
V
S
I
L
L
Site 69
S673
S
E
T
N
K
K
Y
S
N
V
S
I
L
L
T
Site 70
Y686
L
T
E
Q
I
N
L
Y
L
K
M
E
K
K
P
Site 71
T718
K
L
L
K
E
L
D
T
P
F
R
L
Y
G
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation