KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
PLAGL1
Full Name:
Alias:
Lost on transformation 1;Pleiomorphic adenoma-like protein 1;Tumor supressor ZAC
Type:
Mass (Da):
50819
Number AA:
463
UniProt ID:
Q9UM63
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S25
K
F
T
I
H
N
Y
S
H
S
R
E
R
P
Y
Site 2
Y32
S
H
S
R
E
R
P
Y
K
C
V
Q
P
D
C
Site 3
T55
K
L
M
R
H
M
A
T
H
S
P
Q
K
S
H
Site 4
Y100
C
E
E
C
G
K
K
Y
N
T
M
L
G
Y
K
Site 5
Y106
K
Y
N
T
M
L
G
Y
K
R
H
L
A
L
H
Site 6
S149
H
A
E
E
K
P
P
S
G
T
K
E
K
K
H
Site 7
Y166
D
H
C
E
R
C
F
Y
T
R
K
D
V
R
R
Site 8
T200
F
G
R
K
D
H
L
T
R
H
T
K
K
T
H
Site 9
T203
K
D
H
L
T
R
H
T
K
K
T
H
S
Q
E
Site 10
T206
L
T
R
H
T
K
K
T
H
S
Q
E
L
M
K
Site 11
S208
R
H
T
K
K
T
H
S
Q
E
L
M
K
E
S
Site 12
S215
S
Q
E
L
M
K
E
S
L
Q
T
G
D
L
L
Site 13
T218
L
M
K
E
S
L
Q
T
G
D
L
L
S
T
F
Site 14
T224
Q
T
G
D
L
L
S
T
F
H
T
I
S
P
S
Site 15
S255
A
Q
N
G
L
A
S
S
L
P
A
E
V
H
S
Site 16
S262
S
L
P
A
E
V
H
S
L
T
L
S
P
P
E
Site 17
T264
P
A
E
V
H
S
L
T
L
S
P
P
E
Q
A
Site 18
S266
E
V
H
S
L
T
L
S
P
P
E
Q
A
A
Q
Site 19
S281
P
M
Q
P
L
P
E
S
L
A
S
L
H
P
S
Site 20
S284
P
L
P
E
S
L
A
S
L
H
P
S
V
S
P
Site 21
S288
S
L
A
S
L
H
P
S
V
S
P
G
S
P
P
Site 22
S290
A
S
L
H
P
S
V
S
P
G
S
P
P
P
P
Site 23
S293
H
P
S
V
S
P
G
S
P
P
P
P
L
P
N
Site 24
Y303
P
P
L
P
N
H
K
Y
N
T
T
S
T
S
Y
Site 25
T305
L
P
N
H
K
Y
N
T
T
S
T
S
Y
S
P
Site 26
S307
N
H
K
Y
N
T
T
S
T
S
Y
S
P
L
A
Site 27
S309
K
Y
N
T
T
S
T
S
Y
S
P
L
A
S
L
Site 28
Y310
Y
N
T
T
S
T
S
Y
S
P
L
A
S
L
P
Site 29
S311
N
T
T
S
T
S
Y
S
P
L
A
S
L
P
L
Site 30
S315
T
S
Y
S
P
L
A
S
L
P
L
K
A
D
T
Site 31
T322
S
L
P
L
K
A
D
T
K
G
F
C
N
I
S
Site 32
S341
L
P
L
Q
E
P
Q
S
P
Q
K
L
N
P
G
Site 33
T394
W
Q
L
P
P
P
A
T
Q
N
T
F
G
N
S
Site 34
T397
P
P
P
A
T
Q
N
T
F
G
N
S
T
L
A
Site 35
S416
E
S
L
P
H
R
L
S
C
L
G
Q
Q
Q
Q
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation