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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
NAP1L2
Full Name:
Alias:
Brain-specific protein, X-linked
Type:
Mass (Da):
52542
Number AA:
460
UniProt ID:
Q9ULW6
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S11
S
E
N
R
K
E
L
S
E
S
S
Q
E
E
A
Site 2
S13
N
R
K
E
L
S
E
S
S
Q
E
E
A
G
N
Site 3
S14
R
K
E
L
S
E
S
S
Q
E
E
A
G
N
Q
Site 4
T65
E
G
E
N
G
E
D
T
A
A
G
S
G
E
D
Site 5
T79
D
G
K
K
G
G
D
T
D
E
D
S
E
A
D
Site 6
S83
G
G
D
T
D
E
D
S
E
A
D
R
P
K
G
Site 7
S103
L
D
T
D
F
V
E
S
L
P
V
K
V
K
Y
Site 8
S127
T
R
A
A
N
L
E
S
K
F
L
R
E
F
H
Site 9
Y144
E
R
K
F
A
E
M
Y
Q
P
L
L
E
K
R
Site 10
Y159
R
Q
I
I
N
A
I
Y
E
P
T
E
E
E
C
Site 11
Y168
P
T
E
E
E
C
E
Y
K
S
D
S
E
D
C
Site 12
S170
E
E
E
C
E
Y
K
S
D
S
E
D
C
D
D
Site 13
S172
E
C
E
Y
K
S
D
S
E
D
C
D
D
E
E
Site 14
Y186
E
M
C
H
E
E
M
Y
G
N
E
E
G
M
V
Site 15
Y196
E
E
G
M
V
H
E
Y
V
D
E
D
D
G
Y
Site 16
Y203
Y
V
D
E
D
D
G
Y
E
D
Y
Y
Y
D
Y
Site 17
Y206
E
D
D
G
Y
E
D
Y
Y
Y
D
Y
A
V
E
Site 18
Y207
D
D
G
Y
E
D
Y
Y
Y
D
Y
A
V
E
E
Site 19
Y208
D
G
Y
E
D
Y
Y
Y
D
Y
A
V
E
E
E
Site 20
Y210
Y
E
D
Y
Y
Y
D
Y
A
V
E
E
E
E
E
Site 21
T255
L
K
N
V
D
T
L
T
P
L
I
K
K
Y
D
Site 22
Y261
L
T
P
L
I
K
K
Y
D
E
P
I
L
K
L
Site 23
S277
T
D
I
K
V
K
L
S
D
P
G
E
P
L
S
Site 24
S284
S
D
P
G
E
P
L
S
F
T
L
E
F
H
F
Site 25
Y296
F
H
F
K
P
N
E
Y
F
K
N
E
L
L
T
Site 26
T305
K
N
E
L
L
T
K
T
Y
V
L
K
S
K
L
Site 27
Y306
N
E
L
L
T
K
T
Y
V
L
K
S
K
L
A
Site 28
S310
T
K
T
Y
V
L
K
S
K
L
A
Y
Y
D
P
Site 29
Y314
V
L
K
S
K
L
A
Y
Y
D
P
H
P
Y
R
Site 30
Y315
L
K
S
K
L
A
Y
Y
D
P
H
P
Y
R
G
Site 31
T323
D
P
H
P
Y
R
G
T
A
I
E
Y
S
T
G
Site 32
T342
W
N
E
G
K
N
V
T
L
K
T
I
K
K
K
Site 33
T345
G
K
N
V
T
L
K
T
I
K
K
K
Q
K
H
Site 34
T357
Q
K
H
R
I
W
G
T
I
R
T
V
T
E
D
Site 35
T360
R
I
W
G
T
I
R
T
V
T
E
D
F
P
K
Site 36
T362
W
G
T
I
R
T
V
T
E
D
F
P
K
D
S
Site 37
S369
T
E
D
F
P
K
D
S
F
F
N
F
F
S
P
Site 38
S375
D
S
F
F
N
F
F
S
P
H
G
I
T
S
N
Site 39
Y429
R
E
V
N
D
A
I
Y
D
K
I
I
Y
D
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation