KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
DrugProNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
Home
|
Kinexus
|
Contact
|
Credits
Protein Info
Short Name:
CIZ1
Full Name:
CDKN1A INTERACTING ZINC FINGER PROTEIN 1.
Alias:
CDKN1A interacting zinc finger protein 1; LSFR1; NP94; Nuclear protein NP94; Zinc finger protein 356; ZNF356
Type:
Intracellular, Nucleus protein
Mass (Da):
100031
Number AA:
898
UniProt ID:
Q9ULV3
International Prot ID:
IPI00329602
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
Uniprot
OncoNet
Molecular Function:
GO:0003676
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S45
L
Q
Q
L
L
Q
Q
S
P
P
Q
A
P
L
P
Site 2
S56
A
P
L
P
M
A
V
S
R
G
L
P
P
Q
Q
Site 3
S76
L
N
L
Q
G
T
N
S
A
S
L
L
N
G
S
Site 4
Y125
T
L
G
N
L
R
G
Y
G
M
A
S
P
G
L
Site 5
T144
L
T
P
P
Q
L
A
T
P
N
L
Q
Q
F
F
Site 6
S158
F
P
Q
A
T
R
Q
S
L
L
G
P
P
P
V
Site 7
S172
V
G
V
P
M
N
P
S
Q
F
N
L
S
G
R
Site 8
S177
N
P
S
Q
F
N
L
S
G
R
N
P
Q
K
Q
Site 9
S188
P
Q
K
Q
A
R
T
S
S
S
T
T
P
N
R
Site 10
S189
Q
K
Q
A
R
T
S
S
S
T
T
P
N
R
K
Site 11
S190
K
Q
A
R
T
S
S
S
T
T
P
N
R
K
D
Site 12
T191
Q
A
R
T
S
S
S
T
T
P
N
R
K
D
S
Site 13
T192
A
R
T
S
S
S
T
T
P
N
R
K
D
S
S
Site 14
S198
T
T
P
N
R
K
D
S
S
S
Q
T
M
P
V
Site 15
S200
P
N
R
K
D
S
S
S
Q
T
M
P
V
E
D
Site 16
T202
R
K
D
S
S
S
Q
T
M
P
V
E
D
K
S
Site 17
S209
T
M
P
V
E
D
K
S
D
P
P
E
G
S
E
Site 18
S215
K
S
D
P
P
E
G
S
E
E
A
A
E
P
R
Site 19
T225
A
A
E
P
R
M
D
T
P
E
D
Q
D
L
L
Site 20
T244
D
I
A
K
E
K
R
T
P
A
P
E
P
E
P
Site 21
S264
L
P
A
K
R
L
R
S
S
E
E
P
T
E
K
Site 22
S265
P
A
K
R
L
R
S
S
E
E
P
T
E
K
E
Site 23
T269
L
R
S
S
E
E
P
T
E
K
E
P
P
G
Q
Site 24
T288
A
Q
P
Q
A
R
M
T
V
P
K
Q
T
Q
T
Site 25
T293
R
M
T
V
P
K
Q
T
Q
T
P
D
L
L
P
Site 26
T295
T
V
P
K
Q
T
Q
T
P
D
L
L
P
E
A
Site 27
T326
Q
A
Q
V
Q
S
Q
T
Q
P
R
I
P
S
T
Site 28
S332
Q
T
Q
P
R
I
P
S
T
D
T
Q
V
Q
P
Site 29
T333
T
Q
P
R
I
P
S
T
D
T
Q
V
Q
P
K
Site 30
T335
P
R
I
P
S
T
D
T
Q
V
Q
P
K
L
Q
Site 31
T347
K
L
Q
K
Q
A
Q
T
Q
T
S
P
E
H
L
Site 32
S350
K
Q
A
Q
T
Q
T
S
P
E
H
L
V
L
Q
Site 33
S385
Q
V
Q
P
Q
A
H
S
Q
G
P
R
Q
V
Q
Site 34
S413
Q
V
Q
P
Q
A
H
S
Q
P
P
R
Q
V
Q
Site 35
Y432
K
Q
V
Q
T
Q
T
Y
P
Q
V
H
T
Q
A
Site 36
S442
V
H
T
Q
A
Q
P
S
V
Q
P
Q
E
H
P
Site 37
S454
E
H
P
P
A
Q
V
S
V
Q
P
P
E
Q
T
Site 38
T467
Q
T
H
E
Q
P
H
T
Q
P
Q
V
S
L
L
Site 39
T504
A
G
G
G
M
E
K
T
L
P
E
P
V
G
T
Site 40
T511
T
L
P
E
P
V
G
T
Q
V
S
M
E
E
I
Site 41
S514
E
P
V
G
T
Q
V
S
M
E
E
I
Q
N
E
Site 42
T551
A
G
G
S
L
K
V
T
I
L
Q
G
S
D
S
Site 43
S558
T
I
L
Q
G
S
D
S
R
A
F
S
T
V
P
Site 44
S562
G
S
D
S
R
A
F
S
T
V
P
L
T
P
V
Site 45
T563
S
D
S
R
A
F
S
T
V
P
L
T
P
V
P
Site 46
T567
A
F
S
T
V
P
L
T
P
V
P
R
P
S
D
Site 47
S573
L
T
P
V
P
R
P
S
D
S
V
S
S
T
P
Site 48
S575
P
V
P
R
P
S
D
S
V
S
S
T
P
A
A
Site 49
S577
P
R
P
S
D
S
V
S
S
T
P
A
A
T
S
Site 50
S578
R
P
S
D
S
V
S
S
T
P
A
A
T
S
T
Site 51
T579
P
S
D
S
V
S
S
T
P
A
A
T
S
T
P
Site 52
T583
V
S
S
T
P
A
A
T
S
T
P
S
K
Q
A
Site 53
S584
S
S
T
P
A
A
T
S
T
P
S
K
Q
A
L
Site 54
T585
S
T
P
A
A
T
S
T
P
S
K
Q
A
L
Q
Site 55
S587
P
A
A
T
S
T
P
S
K
Q
A
L
Q
F
F
Site 56
T645
V
P
R
D
V
L
E
T
E
D
E
E
P
P
P
Site 57
T673
D
L
I
Q
H
R
R
T
Q
D
H
K
I
A
K
Site 58
S682
D
H
K
I
A
K
Q
S
L
R
P
F
C
T
V
Site 59
T688
Q
S
L
R
P
F
C
T
V
C
N
R
Y
F
K
Site 60
Y693
F
C
T
V
C
N
R
Y
F
K
T
P
R
K
F
Site 61
T696
V
C
N
R
Y
F
K
T
P
R
K
F
V
E
H
Site 62
S706
K
F
V
E
H
V
K
S
Q
G
H
K
D
K
A
Site 63
S718
D
K
A
K
E
L
K
S
L
E
K
E
I
A
G
Site 64
S772
Q
V
R
S
R
D
I
S
R
E
E
W
K
G
S
Site 65
S779
S
R
E
E
W
K
G
S
E
T
Y
S
P
N
T
Site 66
T781
E
E
W
K
G
S
E
T
Y
S
P
N
T
A
Y
Site 67
Y782
E
W
K
G
S
E
T
Y
S
P
N
T
A
Y
G
Site 68
S783
W
K
G
S
E
T
Y
S
P
N
T
A
Y
G
V
Site 69
T786
S
E
T
Y
S
P
N
T
A
Y
G
V
D
F
L
Site 70
Y788
T
Y
S
P
N
T
A
Y
G
V
D
F
L
V
P
Site 71
Y799
F
L
V
P
V
M
G
Y
I
C
R
I
C
H
K
Site 72
S817
S
N
S
G
A
Q
L
S
H
C
K
S
L
G
H
Site 73
S821
A
Q
L
S
H
C
K
S
L
G
H
F
E
N
L
Site 74
Y831
H
F
E
N
L
Q
K
Y
K
A
A
K
N
P
S
Site 75
S838
Y
K
A
A
K
N
P
S
P
T
T
R
P
V
S
Site 76
T840
A
A
K
N
P
S
P
T
T
R
P
V
S
R
R
Site 77
T841
A
K
N
P
S
P
T
T
R
P
V
S
R
R
C
Site 78
S845
S
P
T
T
R
P
V
S
R
R
C
A
I
N
A
Site 79
T861
N
A
L
T
A
L
F
T
S
S
G
R
P
P
S
Site 80
S863
L
T
A
L
F
T
S
S
G
R
P
P
S
Q
P
Site 81
S868
T
S
S
G
R
P
P
S
Q
P
N
T
Q
D
K
Site 82
T872
R
P
P
S
Q
P
N
T
Q
D
K
T
P
S
K
Site 83
T876
Q
P
N
T
Q
D
K
T
P
S
K
V
T
A
R
Site 84
T881
D
K
T
P
S
K
V
T
A
R
P
S
Q
P
P
Site 85
S885
S
K
V
T
A
R
P
S
Q
P
P
L
P
R
R
Site 86
S893
Q
P
P
L
P
R
R
S
T
R
L
K
T
_
_
Site 87
T894
P
P
L
P
R
R
S
T
R
L
K
T
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation