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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
MYO5B
Full Name:
Myosin-Vb
Alias:
KIAA1119; myosin Vb; myosin-5B
Type:
Motor protein
Mass (Da):
213756
Number AA:
1849
UniProt ID:
Q9ULV0
International Prot ID:
IPI00479962
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0016459
Uniprot
OncoNet
Molecular Function:
GO:0005524
GO:0003779
GO:0005516
PhosphoSite+
KinaseNET
Biological Process:
GO:0015031
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S24
D
P
D
E
V
W
R
S
A
E
L
T
K
D
Y
Site 2
T28
V
W
R
S
A
E
L
T
K
D
Y
K
E
G
D
Site 3
Y31
S
A
E
L
T
K
D
Y
K
E
G
D
K
S
L
Site 4
S37
D
Y
K
E
G
D
K
S
L
Q
L
R
L
E
D
Site 5
T46
Q
L
R
L
E
D
E
T
I
L
E
Y
P
I
D
Site 6
Y50
E
D
E
T
I
L
E
Y
P
I
D
V
Q
R
N
Site 7
T75
L
V
G
E
N
D
L
T
A
L
S
Y
L
H
E
Site 8
S78
E
N
D
L
T
A
L
S
Y
L
H
E
P
A
V
Site 9
Y119
P
Y
E
Q
L
P
I
Y
G
Q
D
V
I
Y
A
Site 10
Y125
I
Y
G
Q
D
V
I
Y
A
Y
S
G
Q
N
M
Site 11
S158
A
R
D
E
K
N
Q
S
I
I
V
S
G
E
S
Site 12
S162
K
N
Q
S
I
I
V
S
G
E
S
G
A
G
K
Site 13
T170
G
E
S
G
A
G
K
T
V
S
A
K
Y
A
M
Site 14
S172
S
G
A
G
K
T
V
S
A
K
Y
A
M
R
Y
Site 15
Y175
G
K
T
V
S
A
K
Y
A
M
R
Y
F
A
T
Site 16
Y179
S
A
K
Y
A
M
R
Y
F
A
T
V
G
G
S
Site 17
T182
Y
A
M
R
Y
F
A
T
V
G
G
S
A
S
E
Site 18
S188
A
T
V
G
G
S
A
S
E
T
N
I
E
E
K
Site 19
T190
V
G
G
S
A
S
E
T
N
I
E
E
K
V
L
Site 20
T211
E
A
I
G
N
A
K
T
T
R
N
D
N
S
S
Site 21
T212
A
I
G
N
A
K
T
T
R
N
D
N
S
S
R
Site 22
S217
K
T
T
R
N
D
N
S
S
R
F
G
K
Y
I
Site 23
S218
T
T
R
N
D
N
S
S
R
F
G
K
Y
I
Q
Site 24
Y223
N
S
S
R
F
G
K
Y
I
Q
I
G
F
D
K
Site 25
Y232
Q
I
G
F
D
K
R
Y
H
I
I
G
A
N
M
Site 26
Y242
I
G
A
N
M
R
T
Y
L
L
E
K
S
R
V
Site 27
S247
R
T
Y
L
L
E
K
S
R
V
V
F
Q
A
D
Site 28
Y259
Q
A
D
D
E
R
N
Y
H
I
F
Y
Q
L
C
Site 29
T280
E
F
K
E
L
A
L
T
S
A
E
D
F
F
Y
Site 30
Y287
T
S
A
E
D
F
F
Y
T
S
Q
G
G
D
T
Site 31
S289
A
E
D
F
F
Y
T
S
Q
G
G
D
T
S
I
Site 32
S295
T
S
Q
G
G
D
T
S
I
E
G
V
D
D
A
Site 33
S320
T
L
L
G
V
K
E
S
H
Q
M
S
I
F
K
Site 34
S348
Q
A
E
R
D
G
D
S
C
S
I
S
P
Q
D
Site 35
S350
E
R
D
G
D
S
C
S
I
S
P
Q
D
V
Y
Site 36
S352
D
G
D
S
C
S
I
S
P
Q
D
V
Y
L
S
Site 37
Y357
S
I
S
P
Q
D
V
Y
L
S
N
F
C
R
L
Site 38
S359
S
P
Q
D
V
Y
L
S
N
F
C
R
L
L
G
Site 39
T383
L
C
H
R
K
L
V
T
T
S
E
T
Y
V
K
Site 40
S385
H
R
K
L
V
T
T
S
E
T
Y
V
K
T
M
Site 41
Y388
L
V
T
T
S
E
T
Y
V
K
T
M
S
L
Q
Site 42
T444
L
D
I
Y
G
F
E
T
F
E
V
N
S
F
E
Site 43
Y478
F
K
L
E
Q
E
E
Y
M
K
E
Q
I
P
W
Site 44
Y491
P
W
T
L
I
D
F
Y
D
N
Q
P
C
I
D
Site 45
Y529
Q
N
W
A
Q
K
L
Y
D
R
H
S
S
S
Q
Site 46
S533
Q
K
L
Y
D
R
H
S
S
S
Q
H
F
Q
K
Site 47
S534
K
L
Y
D
R
H
S
S
S
Q
H
F
Q
K
P
Site 48
S535
L
Y
D
R
H
S
S
S
Q
H
F
Q
K
P
R
Site 49
T546
Q
K
P
R
M
S
N
T
A
F
I
I
V
H
F
Site 50
Y559
H
F
A
D
K
V
E
Y
L
S
D
G
F
L
E
Site 51
S561
A
D
K
V
E
Y
L
S
D
G
F
L
E
K
N
Site 52
T571
F
L
E
K
N
R
D
T
V
Y
E
E
Q
I
N
Site 53
Y573
E
K
N
R
D
T
V
Y
E
E
Q
I
N
I
L
Site 54
T602
D
K
D
P
V
P
A
T
T
P
G
K
G
S
S
Site 55
T603
K
D
P
V
P
A
T
T
P
G
K
G
S
S
S
Site 56
S608
A
T
T
P
G
K
G
S
S
S
K
I
S
V
R
Site 57
S609
T
T
P
G
K
G
S
S
S
K
I
S
V
R
S
Site 58
S610
T
P
G
K
G
S
S
S
K
I
S
V
R
S
A
Site 59
S613
K
G
S
S
S
K
I
S
V
R
S
A
R
P
P
Site 60
S616
S
S
K
I
S
V
R
S
A
R
P
P
M
K
V
Site 61
T631
S
N
K
E
H
K
K
T
V
G
H
Q
F
R
T
Site 62
S639
V
G
H
Q
F
R
T
S
L
H
L
L
M
E
T
Site 63
T646
S
L
H
L
L
M
E
T
L
N
A
T
T
P
H
Site 64
Y654
L
N
A
T
T
P
H
Y
V
R
C
I
K
P
N
Site 65
Y694
I
R
I
S
A
A
G
Y
P
S
R
W
A
Y
H
Site 66
T719
K
K
R
E
L
A
N
T
D
K
K
A
I
C
R
Site 67
S727
D
K
K
A
I
C
R
S
V
L
E
N
L
I
K
Site 68
Y755
F
R
A
G
Q
V
A
Y
L
E
K
L
R
A
D
Site 69
T768
A
D
K
F
R
T
A
T
I
M
I
Q
K
T
V
Site 70
T774
A
T
I
M
I
Q
K
T
V
R
G
W
L
Q
K
Site 71
Y784
G
W
L
Q
K
V
K
Y
H
R
L
K
G
A
T
Site 72
T791
Y
H
R
L
K
G
A
T
L
T
L
Q
R
Y
C
Site 73
T793
R
L
K
G
A
T
L
T
L
Q
R
Y
C
R
G
Site 74
Y797
A
T
L
T
L
Q
R
Y
C
R
G
H
L
A
R
Site 75
Y832
M
Q
R
A
R
Q
A
Y
Q
R
V
R
R
A
A
Site 76
T854
R
A
M
F
V
R
R
T
Y
R
Q
V
L
M
E
Site 77
Y855
A
M
F
V
R
R
T
Y
R
Q
V
L
M
E
H
Site 78
T865
V
L
M
E
H
K
A
T
T
I
Q
K
H
V
R
Site 79
S912
A
L
R
I
E
A
R
S
A
E
H
L
K
R
L
Site 80
T943
E
Q
N
K
E
F
K
T
L
S
E
Q
L
S
V
Site 81
S945
N
K
E
F
K
T
L
S
E
Q
L
S
V
T
T
Site 82
S949
K
T
L
S
E
Q
L
S
V
T
T
S
T
Y
T
Site 83
S953
E
Q
L
S
V
T
T
S
T
Y
T
M
E
V
E
Site 84
T956
S
V
T
T
S
T
Y
T
M
E
V
E
R
L
K
Site 85
Y969
L
K
K
E
L
V
H
Y
Q
Q
S
P
G
E
D
Site 86
S972
E
L
V
H
Y
Q
Q
S
P
G
E
D
T
S
L
Site 87
S978
Q
S
P
G
E
D
T
S
L
R
L
Q
E
E
V
Site 88
S987
R
L
Q
E
E
V
E
S
L
R
T
E
L
Q
R
Site 89
T990
E
E
V
E
S
L
R
T
E
L
Q
R
A
H
S
Site 90
S997
T
E
L
Q
R
A
H
S
E
R
K
I
L
E
D
Site 91
S1007
K
I
L
E
D
A
H
S
R
E
K
D
E
L
R
Site 92
S1050
K
D
E
F
A
Q
N
S
V
K
E
N
L
L
M
Site 93
S1106
R
R
N
P
S
N
Q
S
S
L
E
S
D
S
N
Site 94
S1233
D
Q
A
T
Q
N
N
S
S
H
G
S
P
D
S
Site 95
S1290
E
P
N
I
N
A
R
S
S
W
P
N
S
E
K
Site 96
S1643
P
T
G
Y
R
K
R
S
S
S
M
A
D
G
D
Site 97
S1644
T
G
Y
R
K
R
S
S
S
M
A
D
G
D
N
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation