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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
CADPS
Full Name:
Calcium-dependent secretion activator 1
Alias:
Ca++-dependent secretion activator; Ca2+-dependent activator protein for secretion; Ca2+-regulated cytoskeletal protein; Calcium-dependent activator protein for secretion 1; CAPS; CAPS1; CAPS-1; KIAA1121
Type:
Cytoplasmic vesicle membrane, Membrane, Cytosol, Synapse, Cytoplasmic vesicle, Cell junction protein
Mass (Da):
152786
Number AA:
1353
UniProt ID:
Q9ULU8
International Prot ID:
IPI00297412
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0030054
GO:0031410
GO:0005829
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0008289
PhosphoSite+
KinaseNET
Biological Process:
GO:0006887
GO:0015031
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S5
_
_
_
M
L
D
P
S
S
S
E
E
E
S
D
Site 2
S6
_
_
M
L
D
P
S
S
S
E
E
E
S
D
E
Site 3
S7
_
M
L
D
P
S
S
S
E
E
E
S
D
E
I
Site 4
S11
P
S
S
S
E
E
E
S
D
E
I
V
E
E
E
Site 5
S26
S
G
K
E
V
L
G
S
A
P
S
G
A
R
L
Site 6
S29
E
V
L
G
S
A
P
S
G
A
R
L
S
P
S
Site 7
S34
A
P
S
G
A
R
L
S
P
S
R
T
S
E
G
Site 8
S36
S
G
A
R
L
S
P
S
R
T
S
E
G
S
A
Site 9
T38
A
R
L
S
P
S
R
T
S
E
G
S
A
G
S
Site 10
S39
R
L
S
P
S
R
T
S
E
G
S
A
G
S
A
Site 11
S42
P
S
R
T
S
E
G
S
A
G
S
A
G
L
G
Site 12
S45
T
S
E
G
S
A
G
S
A
G
L
G
G
G
G
Site 13
S67
G
A
G
G
G
G
G
S
G
A
S
S
G
G
G
Site 14
S70
G
G
G
G
S
G
A
S
S
G
G
G
A
G
G
Site 15
S71
G
G
G
S
G
A
S
S
G
G
G
A
G
G
L
Site 16
S81
G
A
G
G
L
Q
P
S
S
R
A
G
G
G
R
Site 17
S82
A
G
G
L
Q
P
S
S
R
A
G
G
G
R
P
Site 18
S90
R
A
G
G
G
R
P
S
S
P
S
P
S
V
V
Site 19
S91
A
G
G
G
R
P
S
S
P
S
P
S
V
V
S
Site 20
S93
G
G
R
P
S
S
P
S
P
S
V
V
S
E
K
Site 21
S95
R
P
S
S
P
S
P
S
V
V
S
E
K
E
K
Site 22
S98
S
P
S
P
S
V
V
S
E
K
E
K
E
E
L
Site 23
S149
A
R
R
Q
Q
K
I
S
K
Q
Q
L
Q
T
V
Site 24
Y184
M
N
A
V
Q
S
Y
Y
E
V
F
L
K
S
D
Site 25
S199
R
V
A
R
M
V
Q
S
G
G
C
S
A
N
D
Site 26
S203
M
V
Q
S
G
G
C
S
A
N
D
S
R
E
V
Site 27
S207
G
G
C
S
A
N
D
S
R
E
V
F
K
K
H
Site 28
S221
H
I
E
K
R
V
R
S
L
P
E
I
D
G
L
Site 29
S229
L
P
E
I
D
G
L
S
K
E
T
V
L
S
S
Site 30
S235
L
S
K
E
T
V
L
S
S
W
M
A
K
F
D
Site 31
S236
S
K
E
T
V
L
S
S
W
M
A
K
F
D
A
Site 32
Y245
M
A
K
F
D
A
I
Y
R
G
E
E
D
P
R
Site 33
T259
R
K
Q
Q
A
R
M
T
A
S
A
A
S
E
L
Site 34
S261
Q
Q
A
R
M
T
A
S
A
A
S
E
L
I
L
Site 35
S269
A
A
S
E
L
I
L
S
K
E
Q
L
Y
E
M
Site 36
Y292
K
F
E
H
Q
L
L
Y
N
A
C
Q
L
D
N
Site 37
Y339
S
K
E
M
E
N
M
Y
I
E
E
L
K
S
S
Site 38
S360
N
L
E
S
M
P
V
S
K
G
G
E
F
K
L
Site 39
S373
K
L
Q
K
L
K
R
S
H
N
A
S
I
I
D
Site 40
S377
L
K
R
S
H
N
A
S
I
I
D
M
G
E
E
Site 41
S385
I
I
D
M
G
E
E
S
E
N
Q
L
S
K
S
Site 42
S390
E
E
S
E
N
Q
L
S
K
S
D
V
V
L
S
Site 43
S392
S
E
N
Q
L
S
K
S
D
V
V
L
S
F
S
Site 44
T422
P
N
R
I
V
Y
C
T
M
E
V
E
G
G
E
Site 45
T433
E
G
G
E
K
L
Q
T
D
Q
A
E
A
S
K
Site 46
S450
W
G
T
Q
G
D
F
S
T
T
H
A
L
P
A
Site 47
T451
G
T
Q
G
D
F
S
T
T
H
A
L
P
A
V
Site 48
T485
G
R
V
I
L
H
P
T
P
N
S
P
K
Q
S
Site 49
S488
I
L
H
P
T
P
N
S
P
K
Q
S
E
W
H
Site 50
T498
Q
S
E
W
H
K
M
T
V
S
K
N
C
P
D
Site 51
Y527
Q
N
M
K
H
S
G
Y
L
W
A
I
G
K
N
Site 52
Y575
E
L
L
Q
L
D
G
Y
T
V
D
Y
T
D
P
Site 53
T576
L
L
Q
L
D
G
Y
T
V
D
Y
T
D
P
Q
Site 54
Y579
L
D
G
Y
T
V
D
Y
T
D
P
Q
P
G
L
Site 55
T580
D
G
Y
T
V
D
Y
T
D
P
Q
P
G
L
E
Site 56
T601
N
A
V
K
E
G
D
T
V
I
F
A
S
D
D
Site 57
S606
G
D
T
V
I
F
A
S
D
D
E
Q
D
R
I
Site 58
Y620
I
L
W
V
Q
A
M
Y
R
A
T
G
Q
S
H
Site 59
T623
V
Q
A
M
Y
R
A
T
G
Q
S
H
K
P
V
Site 60
S626
M
Y
R
A
T
G
Q
S
H
K
P
V
P
P
T
Site 61
T633
S
H
K
P
V
P
P
T
Q
V
Q
K
L
N
A
Site 62
S653
P
Q
L
D
A
P
I
S
Q
F
Y
A
D
R
A
Site 63
S671
G
M
D
E
F
I
S
S
N
P
C
N
F
D
H
Site 64
T689
F
E
M
V
Q
R
L
T
L
D
H
R
L
N
D
Site 65
Y698
D
H
R
L
N
D
S
Y
S
C
L
G
W
F
S
Site 66
Y715
Q
V
F
V
L
D
E
Y
C
A
R
N
G
V
R
Site 67
Y730
G
C
H
R
H
L
C
Y
L
R
D
L
L
E
R
Site 68
T770
N
R
P
D
G
I
G
T
V
T
V
E
E
K
E
Site 69
T772
P
D
G
I
G
T
V
T
V
E
E
K
E
R
F
Site 70
T836
V
P
Q
E
E
V
K
T
V
I
R
K
C
L
E
Site 71
Y850
E
Q
A
A
L
V
N
Y
S
R
L
S
E
Y
A
Site 72
S854
L
V
N
Y
S
R
L
S
E
Y
A
K
I
E
E
Site 73
T874
E
N
V
G
R
L
I
T
P
A
K
K
L
E
D
Site 74
T882
P
A
K
K
L
E
D
T
I
R
L
A
E
L
V
Site 75
T944
L
E
V
Q
P
P
D
T
W
D
S
F
P
L
F
Site 76
S947
Q
P
P
D
T
W
D
S
F
P
L
F
Q
L
L
Site 77
Y962
N
D
F
L
R
T
D
Y
N
L
C
N
G
K
F
Site 78
S991
Y
V
D
L
M
E
S
S
I
A
Q
S
I
H
R
Site 79
S995
M
E
S
S
I
A
Q
S
I
H
R
G
F
E
R
Site 80
S1004
H
R
G
F
E
R
E
S
W
E
P
V
K
S
L
Site 81
S1010
E
S
W
E
P
V
K
S
L
T
S
N
L
P
N
Site 82
Y1055
P
S
W
M
A
A
I
Y
D
A
D
N
G
S
G
Site 83
T1122
F
E
V
K
L
Q
K
T
S
R
S
T
D
F
R
Site 84
T1126
L
Q
K
T
S
R
S
T
D
F
R
V
P
Q
S
Site 85
Y1162
E
M
G
Q
E
H
Q
Y
H
S
K
I
D
E
L
Site 86
S1197
E
G
V
L
A
K
L
S
R
Y
D
E
G
T
L
Site 87
Y1199
V
L
A
K
L
S
R
Y
D
E
G
T
L
F
S
Site 88
T1203
L
S
R
Y
D
E
G
T
L
F
S
S
F
L
S
Site 89
S1217
S
F
T
V
K
A
A
S
K
Y
V
D
V
P
K
Site 90
Y1219
T
V
K
A
A
S
K
Y
V
D
V
P
K
P
G
Site 91
T1235
D
V
A
D
A
Y
V
T
F
V
R
H
S
Q
D
Site 92
S1240
Y
V
T
F
V
R
H
S
Q
D
V
L
R
D
K
Site 93
Y1253
D
K
V
N
E
E
M
Y
I
E
R
L
F
D
Q
Site 94
Y1262
E
R
L
F
D
Q
W
Y
N
S
S
M
N
V
I
Site 95
T1296
L
I
R
M
V
K
K
T
Y
R
D
F
R
L
Q
Site 96
S1308
R
L
Q
G
V
L
D
S
T
L
N
S
K
T
Y
Site 97
T1309
L
Q
G
V
L
D
S
T
L
N
S
K
T
Y
E
Site 98
S1312
V
L
D
S
T
L
N
S
K
T
Y
E
T
I
R
Site 99
Y1315
S
T
L
N
S
K
T
Y
E
T
I
R
N
R
L
Site 100
T1317
L
N
S
K
T
Y
E
T
I
R
N
R
L
T
V
Site 101
T1323
E
T
I
R
N
R
L
T
V
E
E
A
T
A
S
Site 102
S1330
T
V
E
E
A
T
A
S
V
S
E
G
G
G
L
Site 103
S1332
E
E
A
T
A
S
V
S
E
G
G
G
L
Q
G
Site 104
S1341
G
G
G
L
Q
G
I
S
M
K
D
S
D
E
E
Site 105
S1345
Q
G
I
S
M
K
D
S
D
E
E
D
E
E
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation