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Updated November 2019
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Protein Info
Short Name:
YEATS2
Full Name:
ISOFORM 1 OF YEATS DOMAIN-CONTAINING PROTEIN 2.
Alias:
CDNA FLJ13308 fis, clone OVARC1001436, weakly similar to ENL PROTEIN; FLJ10201; FLJ12841; FLJ13308; KIAA1197; YEATS domain containing 2; YETS2
Type:
Uncharacterized protein
Mass (Da):
150782
Number AA:
1422
UniProt ID:
Q9ULM3
International Prot ID:
IPI00008200
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005634
GO:0043226
GO:0043227
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
GO:0006355
GO:0009889
GO:0010468
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T11
I
K
R
T
I
K
E
T
D
P
D
Y
E
D
V
Site 2
Y15
I
K
E
T
D
P
D
Y
E
D
V
S
V
A
L
Site 3
S19
D
P
D
Y
E
D
V
S
V
A
L
P
N
K
R
Site 4
S33
R
H
K
A
I
E
N
S
A
R
D
A
A
V
Q
Site 5
S96
S
A
G
L
L
K
V
S
E
G
S
K
T
C
D
Site 6
T101
K
V
S
E
G
S
K
T
C
D
T
M
V
F
N
Site 7
T104
E
G
S
K
T
C
D
T
M
V
F
N
H
P
A
Site 8
S118
A
I
K
K
F
L
E
S
P
S
R
S
S
S
P
Site 9
S120
K
K
F
L
E
S
P
S
R
S
S
S
P
A
N
Site 10
S122
F
L
E
S
P
S
R
S
S
S
P
A
N
Q
R
Site 11
S123
L
E
S
P
S
R
S
S
S
P
A
N
Q
R
A
Site 12
S124
E
S
P
S
R
S
S
S
P
A
N
Q
R
A
E
Site 13
T132
P
A
N
Q
R
A
E
T
P
S
A
N
H
S
E
Site 14
S134
N
Q
R
A
E
T
P
S
A
N
H
S
E
S
D
Site 15
S138
E
T
P
S
A
N
H
S
E
S
D
S
L
S
Q
Site 16
S140
P
S
A
N
H
S
E
S
D
S
L
S
Q
H
N
Site 17
S142
A
N
H
S
E
S
D
S
L
S
Q
H
N
D
F
Site 18
S144
H
S
E
S
D
S
L
S
Q
H
N
D
F
L
S
Site 19
S151
S
Q
H
N
D
F
L
S
D
K
D
N
N
S
N
Site 20
S157
L
S
D
K
D
N
N
S
N
M
D
I
E
E
R
Site 21
S166
M
D
I
E
E
R
L
S
N
N
M
E
Q
R
P
Site 22
S174
N
N
M
E
Q
R
P
S
R
N
T
G
R
D
T
Site 23
T177
E
Q
R
P
S
R
N
T
G
R
D
T
S
R
I
Site 24
T181
S
R
N
T
G
R
D
T
S
R
I
T
G
S
H
Site 25
S182
R
N
T
G
R
D
T
S
R
I
T
G
S
H
K
Site 26
T185
G
R
D
T
S
R
I
T
G
S
H
K
T
E
Q
Site 27
T198
E
Q
R
N
A
D
L
T
D
E
T
S
R
L
F
Site 28
T201
N
A
D
L
T
D
E
T
S
R
L
F
V
K
K
Site 29
T209
S
R
L
F
V
K
K
T
I
V
V
G
N
V
S
Site 30
Y218
V
V
G
N
V
S
K
Y
I
P
P
D
K
R
E
Site 31
Y237
S
T
H
K
W
M
V
Y
V
R
G
S
R
R
E
Site 32
S241
W
M
V
Y
V
R
G
S
R
R
E
P
S
I
N
Site 33
S246
R
G
S
R
R
E
P
S
I
N
H
F
V
K
K
Site 34
T278
R
E
P
P
F
H
L
T
R
R
G
W
G
E
F
Site 35
T312
H
N
L
K
L
D
R
T
Y
T
G
L
Q
T
L
Site 36
Y313
N
L
K
L
D
R
T
Y
T
G
L
Q
T
L
G
Site 37
T314
L
K
L
D
R
T
Y
T
G
L
Q
T
L
G
A
Site 38
S333
D
V
E
L
H
R
H
S
L
G
E
D
C
I
Y
Site 39
Y340
S
L
G
E
D
C
I
Y
P
Q
S
S
E
S
D
Site 40
S343
E
D
C
I
Y
P
Q
S
S
E
S
D
I
S
D
Site 41
S344
D
C
I
Y
P
Q
S
S
E
S
D
I
S
D
A
Site 42
S349
Q
S
S
E
S
D
I
S
D
A
P
P
S
L
P
Site 43
S367
P
A
P
V
K
A
S
S
P
I
K
Q
S
H
E
Site 44
S372
A
S
S
P
I
K
Q
S
H
E
P
V
P
D
T
Site 45
T379
S
H
E
P
V
P
D
T
S
V
E
K
G
F
P
Site 46
S380
H
E
P
V
P
D
T
S
V
E
K
G
F
P
A
Site 47
S388
V
E
K
G
F
P
A
S
T
E
A
E
R
H
T
Site 48
T395
S
T
E
A
E
R
H
T
P
F
Y
A
L
P
S
Site 49
Y398
A
E
R
H
T
P
F
Y
A
L
P
S
S
L
E
Site 50
S402
T
P
F
Y
A
L
P
S
S
L
E
R
T
P
T
Site 51
S403
P
F
Y
A
L
P
S
S
L
E
R
T
P
T
K
Site 52
T407
L
P
S
S
L
E
R
T
P
T
K
M
T
T
S
Site 53
T409
S
S
L
E
R
T
P
T
K
M
T
T
S
Q
K
Site 54
S414
T
P
T
K
M
T
T
S
Q
K
V
T
F
C
S
Site 55
T418
M
T
T
S
Q
K
V
T
F
C
S
H
G
N
S
Site 56
S421
S
Q
K
V
T
F
C
S
H
G
N
S
A
F
Q
Site 57
S425
T
F
C
S
H
G
N
S
A
F
Q
P
I
A
S
Site 58
S440
S
C
K
I
V
P
Q
S
Q
V
P
N
P
E
S
Site 59
S447
S
Q
V
P
N
P
E
S
P
G
K
S
F
Q
P
Site 60
S451
N
P
E
S
P
G
K
S
F
Q
P
I
T
M
S
Site 61
S463
T
M
S
C
K
I
V
S
G
S
P
I
S
T
P
Site 62
S465
S
C
K
I
V
S
G
S
P
I
S
T
P
S
P
Site 63
S468
I
V
S
G
S
P
I
S
T
P
S
P
S
P
L
Site 64
T469
V
S
G
S
P
I
S
T
P
S
P
S
P
L
P
Site 65
S471
G
S
P
I
S
T
P
S
P
S
P
L
P
R
T
Site 66
S473
P
I
S
T
P
S
P
S
P
L
P
R
T
P
T
Site 67
T478
S
P
S
P
L
P
R
T
P
T
S
T
P
V
H
Site 68
T480
S
P
L
P
R
T
P
T
S
T
P
V
H
V
K
Site 69
S481
P
L
P
R
T
P
T
S
T
P
V
H
V
K
Q
Site 70
T482
L
P
R
T
P
T
S
T
P
V
H
V
K
Q
G
Site 71
S493
V
K
Q
G
T
A
G
S
V
I
N
N
P
Y
V
Site 72
Y499
G
S
V
I
N
N
P
Y
V
I
M
D
K
Q
P
Site 73
T513
P
G
Q
V
I
G
A
T
T
P
S
T
G
S
P
Site 74
T514
G
Q
V
I
G
A
T
T
P
S
T
G
S
P
T
Site 75
S516
V
I
G
A
T
T
P
S
T
G
S
P
T
N
K
Site 76
T517
I
G
A
T
T
P
S
T
G
S
P
T
N
K
I
Site 77
S519
A
T
T
P
S
T
G
S
P
T
N
K
I
S
T
Site 78
T521
T
P
S
T
G
S
P
T
N
K
I
S
T
A
S
Site 79
S525
G
S
P
T
N
K
I
S
T
A
S
Q
V
S
Q
Site 80
S528
T
N
K
I
S
T
A
S
Q
V
S
Q
G
T
G
Site 81
S531
I
S
T
A
S
Q
V
S
Q
G
T
G
S
P
V
Site 82
T534
A
S
Q
V
S
Q
G
T
G
S
P
V
P
K
I
Site 83
S536
Q
V
S
Q
G
T
G
S
P
V
P
K
I
H
G
Site 84
T548
I
H
G
S
S
F
V
T
S
T
V
K
Q
E
D
Site 85
S549
H
G
S
S
F
V
T
S
T
V
K
Q
E
D
S
Site 86
T550
G
S
S
F
V
T
S
T
V
K
Q
E
D
S
L
Site 87
S556
S
T
V
K
Q
E
D
S
L
F
A
S
M
P
P
Site 88
S569
P
P
L
C
P
I
G
S
H
P
K
V
Q
S
P
Site 89
S575
G
S
H
P
K
V
Q
S
P
K
P
I
T
G
G
Site 90
T604
E
A
P
H
V
P
A
T
G
A
A
S
Q
S
P
Site 91
S608
V
P
A
T
G
A
A
S
Q
S
P
L
P
Q
Y
Site 92
S610
A
T
G
A
A
S
Q
S
P
L
P
Q
Y
V
T
Site 93
Y615
S
Q
S
P
L
P
Q
Y
V
T
V
K
G
G
H
Site 94
T617
S
P
L
P
Q
Y
V
T
V
K
G
G
H
M
I
Site 95
S627
G
G
H
M
I
A
V
S
P
Q
K
Q
V
I
T
Site 96
T634
S
P
Q
K
Q
V
I
T
P
G
E
G
I
A
Q
Site 97
S642
P
G
E
G
I
A
Q
S
A
K
V
Q
P
S
K
Site 98
S657
V
V
G
V
P
V
G
S
A
L
P
S
T
V
K
Site 99
S684
A
K
A
S
S
S
V
S
K
A
V
G
P
K
Q
Site 100
S730
T
A
A
G
P
Q
K
S
G
S
Q
G
S
V
M
Site 101
S732
A
G
P
Q
K
S
G
S
Q
G
S
V
M
A
T
Site 102
S735
Q
K
S
G
S
Q
G
S
V
M
A
T
L
Q
L
Site 103
T739
S
Q
G
S
V
M
A
T
L
Q
L
P
A
T
N
Site 104
Y760
L
P
P
G
T
K
L
Y
L
T
T
N
S
K
N
Site 105
T762
P
G
T
K
L
Y
L
T
T
N
S
K
N
P
S
Site 106
T763
G
T
K
L
Y
L
T
T
N
S
K
N
P
S
G
Site 107
S765
K
L
Y
L
T
T
N
S
K
N
P
S
G
K
G
Site 108
S769
T
T
N
S
K
N
P
S
G
K
G
K
L
L
L
Site 109
T786
Q
G
A
I
L
R
A
T
N
N
A
N
L
Q
S
Site 110
S793
T
N
N
A
N
L
Q
S
G
S
A
A
S
G
G
Site 111
S795
N
A
N
L
Q
S
G
S
A
A
S
G
G
S
G
Site 112
S815
G
G
G
G
G
G
G
S
G
S
G
G
G
G
S
Site 113
S817
G
G
G
G
G
S
G
S
G
G
G
G
S
T
G
Site 114
S822
S
G
S
G
G
G
G
S
T
G
G
G
G
G
T
Site 115
S836
T
A
G
G
G
T
Q
S
T
A
G
P
G
G
I
Site 116
T837
A
G
G
G
T
Q
S
T
A
G
P
G
G
I
S
Site 117
S844
T
A
G
P
G
G
I
S
Q
H
L
T
Y
T
S
Site 118
T848
G
G
I
S
Q
H
L
T
Y
T
S
Y
I
L
K
Site 119
Y849
G
I
S
Q
H
L
T
Y
T
S
Y
I
L
K
Q
Site 120
T861
L
K
Q
T
P
Q
G
T
F
L
V
G
Q
P
S
Site 121
S868
T
F
L
V
G
Q
P
S
P
Q
T
S
G
K
Q
Site 122
S872
G
Q
P
S
P
Q
T
S
G
K
Q
L
T
T
G
Site 123
S880
G
K
Q
L
T
T
G
S
V
V
Q
G
T
L
G
Site 124
S889
V
Q
G
T
L
G
V
S
T
S
S
A
Q
G
Q
Site 125
S891
G
T
L
G
V
S
T
S
S
A
Q
G
Q
Q
T
Site 126
T898
S
S
A
Q
G
Q
Q
T
L
K
V
I
S
G
Q
Site 127
T907
K
V
I
S
G
Q
K
T
T
L
F
T
Q
A
A
Site 128
S920
A
A
H
G
G
Q
A
S
L
M
K
I
S
D
S
Site 129
S925
Q
A
S
L
M
K
I
S
D
S
T
L
K
T
V
Site 130
T931
I
S
D
S
T
L
K
T
V
P
A
T
S
Q
L
Site 131
S936
L
K
T
V
P
A
T
S
Q
L
S
K
P
G
T
Site 132
S939
V
P
A
T
S
Q
L
S
K
P
G
T
T
M
L
Site 133
T943
S
Q
L
S
K
P
G
T
T
M
L
R
V
A
G
Site 134
S964
T
S
P
A
V
A
L
S
A
N
G
P
A
Q
Q
Site 135
S979
S
E
G
M
A
P
V
S
S
S
T
V
S
S
V
Site 136
S984
P
V
S
S
S
T
V
S
S
V
T
K
T
S
G
Site 137
S985
V
S
S
S
T
V
S
S
V
T
K
T
S
G
Q
Site 138
T989
T
V
S
S
V
T
K
T
S
G
Q
Q
Q
V
C
Site 139
T1021
S
A
T
S
L
V
P
T
P
N
P
I
S
G
K
Site 140
S1026
V
P
T
P
N
P
I
S
G
K
A
T
V
S
G
Site 141
S1039
S
G
L
L
K
I
H
S
S
Q
S
S
P
Q
Q
Site 142
S1040
G
L
L
K
I
H
S
S
Q
S
S
P
Q
Q
A
Site 143
S1043
K
I
H
S
S
Q
S
S
P
Q
Q
A
V
L
T
Site 144
T1050
S
P
Q
Q
A
V
L
T
I
P
S
Q
L
K
P
Site 145
S1059
P
S
Q
L
K
P
L
S
V
N
T
S
G
G
V
Site 146
T1068
N
T
S
G
G
V
Q
T
I
L
M
P
V
N
K
Site 147
S1079
P
V
N
K
V
V
Q
S
F
S
T
S
K
P
P
Site 148
S1081
N
K
V
V
Q
S
F
S
T
S
K
P
P
A
I
Site 149
T1111
A
A
V
A
K
V
K
T
E
P
E
T
P
G
P
Site 150
T1115
K
V
K
T
E
P
E
T
P
G
P
S
C
L
S
Site 151
S1122
T
P
G
P
S
C
L
S
Q
E
G
Q
T
A
V
Site 152
T1131
E
G
Q
T
A
V
K
T
E
E
S
S
E
L
G
Site 153
S1134
T
A
V
K
T
E
E
S
S
E
L
G
N
Y
V
Site 154
S1135
A
V
K
T
E
E
S
S
E
L
G
N
Y
V
I
Site 155
Y1140
E
S
S
E
L
G
N
Y
V
I
K
I
D
H
L
Site 156
S1168
I
P
L
I
T
A
K
S
E
D
A
S
C
F
S
Site 157
S1172
T
A
K
S
E
D
A
S
C
F
S
A
K
S
V
Site 158
S1175
S
E
D
A
S
C
F
S
A
K
S
V
E
Q
Y
Site 159
Y1182
S
A
K
S
V
E
Q
Y
Y
G
W
N
I
G
K
Site 160
Y1183
A
K
S
V
E
Q
Y
Y
G
W
N
I
G
K
R
Site 161
T1200
A
E
W
Q
R
A
M
T
M
R
K
V
L
Q
E
Site 162
T1219
N
P
R
F
H
H
L
T
P
L
K
T
K
H
I
Site 163
T1236
W
C
R
C
H
G
Y
T
P
P
D
P
E
S
L
Site 164
S1242
Y
T
P
P
D
P
E
S
L
R
N
D
G
D
S
Site 165
S1249
S
L
R
N
D
G
D
S
I
E
D
V
L
T
Q
Site 166
T1255
D
S
I
E
D
V
L
T
Q
I
D
S
E
P
E
Site 167
S1259
D
V
L
T
Q
I
D
S
E
P
E
C
P
S
S
Site 168
S1265
D
S
E
P
E
C
P
S
S
F
S
S
A
D
N
Site 169
S1266
S
E
P
E
C
P
S
S
F
S
S
A
D
N
L
Site 170
S1268
P
E
C
P
S
S
F
S
S
A
D
N
L
C
R
Site 171
S1269
E
C
P
S
S
F
S
S
A
D
N
L
C
R
K
Site 172
S1298
E
E
E
V
D
I
L
S
L
S
E
P
V
K
I
Site 173
Y1321
K
Q
E
E
V
K
F
Y
L
P
P
T
P
G
S
Site 174
S1328
Y
L
P
P
T
P
G
S
E
F
I
G
D
V
T
Site 175
Y1352
V
A
L
H
R
N
V
Y
A
S
V
V
E
D
M
Site 176
Y1380
R
Q
A
L
A
V
G
Y
Q
T
A
S
H
N
R
Site 177
S1384
A
V
G
Y
Q
T
A
S
H
N
R
I
P
K
E
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation