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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
ZNF490
Full Name:
Alias:
Type:
Mass (Da):
61340
Number AA:
529
UniProt ID:
Q9ULM2
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S6
_
_
M
R
R
N
S
S
L
S
F
Q
M
E
R
Site 2
S8
M
R
R
N
S
S
L
S
F
Q
M
E
R
P
L
Site 3
S21
P
L
E
E
Q
V
Q
S
K
W
S
S
S
Q
G
Site 4
S25
Q
V
Q
S
K
W
S
S
S
Q
G
R
T
G
T
Site 5
S26
V
Q
S
K
W
S
S
S
Q
G
R
T
G
T
G
Site 6
T30
W
S
S
S
Q
G
R
T
G
T
G
G
S
D
V
Site 7
T32
S
S
Q
G
R
T
G
T
G
G
S
D
V
L
Q
Site 8
S35
G
R
T
G
T
G
G
S
D
V
L
Q
M
Q
N
Site 9
S43
D
V
L
Q
M
Q
N
S
E
H
H
G
Q
S
I
Site 10
T52
H
H
G
Q
S
I
K
T
Q
T
D
S
I
S
L
Site 11
T54
G
Q
S
I
K
T
Q
T
D
S
I
S
L
E
D
Site 12
S56
S
I
K
T
Q
T
D
S
I
S
L
E
D
V
A
Site 13
S58
K
T
Q
T
D
S
I
S
L
E
D
V
A
V
N
Site 14
Y82
D
P
G
Q
R
N
I
Y
R
D
V
M
R
A
T
Site 15
S118
N
Q
G
R
N
L
R
S
P
M
V
E
A
L
C
Site 16
S136
E
D
C
P
C
G
K
S
T
S
Q
I
P
D
L
Site 17
S138
C
P
C
G
K
S
T
S
Q
I
P
D
L
N
T
Site 18
T145
S
Q
I
P
D
L
N
T
N
L
E
T
P
T
G
Site 19
T149
D
L
N
T
N
L
E
T
P
T
G
L
K
P
C
Site 20
T179
N
R
H
M
R
S
H
T
E
Q
K
P
N
E
C
Site 21
Y189
K
P
N
E
C
H
E
Y
G
E
K
P
H
K
C
Site 22
T202
K
C
K
E
C
G
K
T
F
T
R
S
S
S
I
Site 23
T204
K
E
C
G
K
T
F
T
R
S
S
S
I
R
T
Site 24
S206
C
G
K
T
F
T
R
S
S
S
I
R
T
H
E
Site 25
S207
G
K
T
F
T
R
S
S
S
I
R
T
H
E
R
Site 26
S208
K
T
F
T
R
S
S
S
I
R
T
H
E
R
I
Site 27
T211
T
R
S
S
S
I
R
T
H
E
R
I
H
T
G
Site 28
T217
R
T
H
E
R
I
H
T
G
E
K
P
Y
E
C
Site 29
Y222
I
H
T
G
E
K
P
Y
E
C
K
E
C
G
K
Site 30
T245
R
N
H
I
R
I
H
T
G
E
T
P
Y
E
C
Site 31
T248
I
R
I
H
T
G
E
T
P
Y
E
C
K
E
C
Site 32
Y250
I
H
T
G
E
T
P
Y
E
C
K
E
C
G
K
Site 33
Y261
E
C
G
K
A
F
R
Y
L
T
A
L
R
R
H
Site 34
T263
G
K
A
F
R
Y
L
T
A
L
R
R
H
E
K
Site 35
T273
R
R
H
E
K
N
H
T
G
E
K
P
Y
K
C
Site 36
Y289
Q
C
G
K
A
F
I
Y
Y
Q
P
F
L
T
H
Site 37
Y290
C
G
K
A
F
I
Y
Y
Q
P
F
L
T
H
E
Site 38
T295
I
Y
Y
Q
P
F
L
T
H
E
R
T
H
T
G
Site 39
T299
P
F
L
T
H
E
R
T
H
T
G
E
K
P
Y
Site 40
T301
L
T
H
E
R
T
H
T
G
E
K
P
Y
E
C
Site 41
Y306
T
H
T
G
E
K
P
Y
E
C
K
Q
C
G
K
Site 42
S316
K
Q
C
G
K
A
F
S
C
P
T
Y
L
R
S
Site 43
T319
G
K
A
F
S
C
P
T
Y
L
R
S
H
E
K
Site 44
Y320
K
A
F
S
C
P
T
Y
L
R
S
H
E
K
T
Site 45
S323
S
C
P
T
Y
L
R
S
H
E
K
T
H
T
G
Site 46
T327
Y
L
R
S
H
E
K
T
H
T
G
E
K
P
F
Site 47
T329
R
S
H
E
K
T
H
T
G
E
K
P
F
V
C
Site 48
S345
E
C
G
R
A
F
F
S
H
S
S
L
R
K
H
Site 49
S347
G
R
A
F
F
S
H
S
S
L
R
K
H
V
K
Site 50
S348
R
A
F
F
S
H
S
S
L
R
K
H
V
K
T
Site 51
T355
S
L
R
K
H
V
K
T
H
T
G
V
Q
P
Y
Site 52
T363
H
T
G
V
Q
P
Y
T
C
K
K
C
G
E
A
Site 53
S373
K
C
G
E
A
F
K
S
S
S
S
C
E
V
H
Site 54
S375
G
E
A
F
K
S
S
S
S
C
E
V
H
E
R
Site 55
S376
E
A
F
K
S
S
S
S
C
E
V
H
E
R
T
Site 56
Y390
T
H
F
G
E
K
P
Y
E
C
K
Q
C
G
K
Site 57
S401
Q
C
G
K
A
F
N
S
S
S
Y
L
Q
L
H
Site 58
S402
C
G
K
A
F
N
S
S
S
Y
L
Q
L
H
E
Site 59
S403
G
K
A
F
N
S
S
S
Y
L
Q
L
H
E
R
Site 60
T413
Q
L
H
E
R
V
H
T
G
E
K
T
Y
E
C
Site 61
T417
R
V
H
T
G
E
K
T
Y
E
C
K
E
C
G
Site 62
Y418
V
H
T
G
E
K
T
Y
E
C
K
E
C
G
K
Site 63
Y429
E
C
G
K
A
F
L
Y
S
T
H
F
R
I
H
Site 64
T431
G
K
A
F
L
Y
S
T
H
F
R
I
H
E
R
Site 65
T439
H
F
R
I
H
E
R
T
H
T
R
E
K
P
Y
Site 66
T441
R
I
H
E
R
T
H
T
R
E
K
P
Y
E
C
Site 67
Y446
T
H
T
R
E
K
P
Y
E
C
K
Q
C
G
R
Site 68
Y457
Q
C
G
R
V
F
I
Y
F
S
H
L
R
R
H
Site 69
S459
G
R
V
F
I
Y
F
S
H
L
R
R
H
E
R
Site 70
S467
H
L
R
R
H
E
R
S
H
T
G
V
K
P
C
Site 71
T469
R
R
H
E
R
S
H
T
G
V
K
P
C
E
C
Site 72
T484
K
Q
C
G
K
A
F
T
C
L
N
S
L
K
V
Site 73
T497
K
V
H
K
R
I
H
T
G
E
R
P
F
Q
C
Site 74
S512
R
Q
C
G
K
A
F
S
Y
S
K
S
L
H
V
Site 75
S514
C
G
K
A
F
S
Y
S
K
S
L
H
V
H
E
Site 76
S516
K
A
F
S
Y
S
K
S
L
H
V
H
E
R
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation