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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
KIAA1239
Full Name:
Leucine-rich repeat and WD repeat-containing protein KIAA1239
Alias:
LOC57495
Type:
Unknown function
Mass (Da):
197466
Number AA:
1742
UniProt ID:
Q9ULI1
International Prot ID:
IPI00166979
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
Uniprot
OncoNet
Molecular Function:
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
T8
M
W
P
A
G
A
G
T
K
L
P
C
P
R
D
Site 2
S16
K
L
P
C
P
R
D
S
A
L
R
R
A
A
F
Site 3
S24
A
L
R
R
A
A
F
S
G
N
L
T
A
L
P
Site 4
Y64
Q
A
L
R
E
N
V
Y
P
K
L
R
E
F
C
Site 5
Y75
R
E
F
C
R
E
N
Y
G
L
E
F
Q
V
I
Site 6
Y85
E
F
Q
V
I
D
L
Y
W
G
V
E
E
D
E
Site 7
S95
V
E
E
D
E
W
D
S
P
E
L
Q
K
T
R
Site 8
T101
D
S
P
E
L
Q
K
T
R
M
K
L
L
E
N
Site 9
Y161
T
K
L
L
E
E
W
Y
C
R
D
E
N
S
V
Site 10
Y173
N
S
V
P
A
A
Y
Y
L
R
P
K
S
E
M
Site 11
S178
A
Y
Y
L
R
P
K
S
E
M
L
R
S
N
R
Site 12
S183
P
K
S
E
M
L
R
S
N
R
N
A
M
Q
P
Site 13
T199
T
N
A
E
N
E
K
T
W
Q
E
I
S
D
E
Site 14
S227
E
K
G
K
M
K
H
S
Q
A
K
R
Y
L
F
Site 15
T249
D
F
A
L
G
K
Q
T
P
A
F
L
K
K
C
Site 16
Y278
K
I
P
E
M
G
K
Y
M
D
I
T
G
T
E
Site 17
T282
M
G
K
Y
M
D
I
T
G
T
E
P
R
I
I
Site 18
T284
K
Y
M
D
I
T
G
T
E
P
R
I
I
R
D
Site 19
Y318
A
S
S
N
L
R
V
Y
T
S
V
T
H
C
D
Site 20
T319
S
S
N
L
R
V
Y
T
S
V
T
H
C
D
M
Site 21
Y338
S
Q
E
I
E
N
H
Y
I
E
G
L
G
K
Q
Site 22
Y347
E
G
L
G
K
Q
F
Y
E
D
M
I
D
I
I
Site 23
T364
T
I
Q
Q
N
F
D
T
E
T
D
T
L
Y
D
Site 24
T368
N
F
D
T
E
T
D
T
L
Y
D
E
I
L
Q
Site 25
Y370
D
T
E
T
D
T
L
Y
D
E
I
L
Q
H
S
Site 26
S378
D
E
I
L
Q
H
S
S
L
C
K
T
Y
A
S
Site 27
T382
Q
H
S
S
L
C
K
T
Y
A
S
F
Y
E
Y
Site 28
Y389
T
Y
A
S
F
Y
E
Y
K
C
E
S
L
N
I
Site 29
Y415
H
I
N
P
L
I
I
Y
G
G
P
C
T
G
K
Site 30
T441
Y
G
W
L
H
E
D
T
G
P
E
S
D
P
V
Site 31
S445
H
E
D
T
G
P
E
S
D
P
V
V
I
V
R
Site 32
T457
I
V
R
F
L
G
T
T
D
M
S
S
D
L
R
Site 33
Y485
Y
R
C
L
V
Q
S
Y
P
K
K
I
H
D
L
Site 34
S544
R
F
V
R
I
V
L
S
T
L
P
N
K
H
G
Site 35
Y566
L
I
H
E
E
D
N
Y
I
E
L
I
P
R
D
Site 36
S578
P
R
D
R
K
M
C
S
Q
V
L
K
H
Q
L
Site 37
T593
L
R
V
K
R
K
V
T
S
G
Q
Q
I
Y
V
Site 38
S594
R
V
K
R
K
V
T
S
G
Q
Q
I
Y
V
N
Site 39
Y599
V
T
S
G
Q
Q
I
Y
V
N
N
A
L
S
K
Site 40
S633
H
K
D
V
D
E
S
S
L
S
V
T
V
H
E
Site 41
S635
D
V
D
E
S
S
L
S
V
T
V
H
E
S
I
Site 42
T637
D
E
S
S
L
S
V
T
V
H
E
S
I
E
Q
Site 43
S648
S
I
E
Q
L
F
W
S
L
E
K
K
C
G
Q
Site 44
S673
T
M
A
K
M
G
L
S
E
M
E
L
E
D
V
Site 45
S686
D
V
L
A
L
D
N
S
V
M
S
E
L
K
E
Site 46
S698
L
K
E
N
T
R
P
S
N
P
L
R
V
P
Y
Site 47
Y705
S
N
P
L
R
V
P
Y
L
Y
I
A
R
L
K
Site 48
Y707
P
L
R
V
P
Y
L
Y
I
A
R
L
K
E
G
Site 49
S716
A
R
L
K
E
G
L
S
G
Y
L
I
E
R
H
Site 50
Y718
L
K
E
G
L
S
G
Y
L
I
E
R
H
V
K
Site 51
S768
D
Y
F
L
G
V
W
S
G
G
R
R
K
A
F
Site 52
S805
K
H
F
M
E
Q
A
S
F
D
R
Q
A
P
D
Site 53
Y839
R
K
M
S
E
L
L
Y
H
L
T
R
C
G
K
Site 54
T842
S
E
L
L
Y
H
L
T
R
C
G
K
T
D
D
Site 55
S875
G
Q
F
D
K
V
L
S
D
I
E
L
A
Y
N
Site 56
S884
I
E
L
A
Y
N
Y
S
Q
E
K
E
L
K
F
Site 57
T895
E
L
K
F
L
A
N
T
L
R
S
I
K
N
K
Site 58
T904
R
S
I
K
N
K
V
T
A
F
P
G
S
L
S
Site 59
S909
K
V
T
A
F
P
G
S
L
S
A
E
L
Q
Q
Site 60
S923
Q
R
L
L
P
V
V
S
S
L
P
K
L
R
H
Site 61
Y942
C
D
K
D
G
P
K
Y
C
S
I
V
P
L
H
Site 62
S944
K
D
G
P
K
Y
C
S
I
V
P
L
H
S
S
Site 63
S951
S
I
V
P
L
H
S
S
M
D
V
T
Y
S
P
Site 64
T955
L
H
S
S
M
D
V
T
Y
S
P
E
R
L
P
Site 65
Y956
H
S
S
M
D
V
T
Y
S
P
E
R
L
P
L
Site 66
S957
S
S
M
D
V
T
Y
S
P
E
R
L
P
L
S
Site 67
S964
S
P
E
R
L
P
L
S
S
S
H
L
H
V
T
Site 68
S965
P
E
R
L
P
L
S
S
S
H
L
H
V
T
E
Site 69
S966
E
R
L
P
L
S
S
S
H
L
H
V
T
E
I
Site 70
S992
A
L
E
N
G
S
I
S
T
W
D
V
E
T
R
Site 71
Y1023
K
L
T
S
D
E
K
Y
L
V
V
A
T
T
N
Site 72
T1052
S
E
V
E
I
K
G
T
K
H
G
S
S
A
T
Site 73
S1057
K
G
T
K
H
G
S
S
A
T
Y
I
N
G
F
Site 74
Y1060
K
H
G
S
S
A
T
Y
I
N
G
F
T
L
S
Site 75
T1135
G
S
G
E
K
L
C
T
V
T
S
E
F
S
G
Site 76
T1137
G
E
K
L
C
T
V
T
S
E
F
S
G
G
F
Site 77
S1162
Q
E
M
V
M
V
D
S
E
G
S
L
S
V
W
Site 78
S1165
V
M
V
D
S
E
G
S
L
S
V
W
N
T
E
Site 79
S1167
V
D
S
E
G
S
L
S
V
W
N
T
E
D
I
Site 80
T1171
G
S
L
S
V
W
N
T
E
D
I
S
S
P
Q
Site 81
S1176
W
N
T
E
D
I
S
S
P
Q
L
T
D
D
F
Site 82
T1180
D
I
S
S
P
Q
L
T
D
D
F
D
C
R
R
Site 83
S1190
F
D
C
R
R
E
D
S
E
V
V
S
I
E
L
Site 84
S1194
R
E
D
S
E
V
V
S
I
E
L
S
E
D
Q
Site 85
S1236
K
H
N
E
R
F
I
S
A
V
L
S
K
N
G
Site 86
S1269
D
T
G
Q
C
M
A
S
L
Q
E
I
S
G
S
Site 87
T1315
A
M
S
N
I
D
K
T
G
K
P
I
Q
S
L
Site 88
S1321
K
T
G
K
P
I
Q
S
L
L
L
P
A
R
G
Site 89
Y1332
P
A
R
G
E
I
I
Y
S
L
D
G
S
D
C
Site 90
T1374
S
T
G
D
I
M
V
T
S
D
D
K
S
S
Q
Site 91
S1375
T
G
D
I
M
V
T
S
D
D
K
S
S
Q
Y
Site 92
S1380
V
T
S
D
D
K
S
S
Q
Y
V
W
H
T
S
Site 93
Y1382
S
D
D
K
S
S
Q
Y
V
W
H
T
S
S
G
Site 94
T1386
S
S
Q
Y
V
W
H
T
S
S
G
E
N
L
F
Site 95
S1401
R
I
N
G
Q
R
I
S
Q
L
L
I
T
H
N
Site 96
S1414
H
N
D
Q
F
V
V
S
L
C
E
E
N
A
S
Site 97
S1421
S
L
C
E
E
N
A
S
R
V
W
R
L
A
T
Site 98
T1428
S
R
V
W
R
L
A
T
G
H
R
V
C
N
I
Site 99
T1470
S
L
W
T
G
S
I
T
K
K
F
C
C
E
D
Site 100
T1509
T
V
N
I
W
S
L
T
D
E
V
I
C
R
R
Site 101
S1533
N
L
E
D
F
E
I
S
P
N
G
K
L
G
I
Site 102
S1564
K
L
R
V
V
H
A
S
G
I
I
W
R
Q
R
Site 103
S1573
I
I
W
R
Q
R
L
S
R
D
G
R
Y
L
V
Site 104
Y1578
R
L
S
R
D
G
R
Y
L
V
Y
I
C
F
R
Site 105
Y1581
R
D
G
R
Y
L
V
Y
I
C
F
R
N
G
E
Site 106
S1614
G
K
N
I
G
A
C
S
L
Y
K
T
P
T
F
Site 107
T1620
C
S
L
Y
K
T
P
T
F
L
A
L
S
Q
R
Site 108
Y1643
D
D
G
S
I
G
I
Y
T
V
V
D
R
V
D
Site 109
S1660
L
K
I
K
I
A
T
S
N
S
R
Q
I
F
N
Site 110
T1670
R
Q
I
F
N
N
A
T
H
T
S
R
P
K
C
Site 111
T1672
I
F
N
N
A
T
H
T
S
R
P
K
C
N
S
Site 112
S1679
T
S
R
P
K
C
N
S
Y
C
F
K
I
S
V
Site 113
Y1680
S
R
P
K
C
N
S
Y
C
F
K
I
S
V
D
Site 114
S1685
N
S
Y
C
F
K
I
S
V
D
C
L
W
R
E
Site 115
T1694
D
C
L
W
R
E
S
T
E
V
F
A
R
D
S
Site 116
S1701
T
E
V
F
A
R
D
S
P
I
T
V
S
D
S
Site 117
T1704
F
A
R
D
S
P
I
T
V
S
D
S
T
E
S
Site 118
S1706
R
D
S
P
I
T
V
S
D
S
T
E
S
N
E
Site 119
S1708
S
P
I
T
V
S
D
S
T
E
S
N
E
A
T
Site 120
S1711
T
V
S
D
S
T
E
S
N
E
A
T
P
S
K
Site 121
T1715
S
T
E
S
N
E
A
T
P
S
K
K
H
N
S
Site 122
S1717
E
S
N
E
A
T
P
S
K
K
H
N
S
C
Y
Site 123
Y1724
S
K
K
H
N
S
C
Y
E
R
V
C
S
A
L
Site 124
S1729
S
C
Y
E
R
V
C
S
A
L
E
A
R
G
H
Site 125
S1737
A
L
E
A
R
G
H
S
Y
A
P
D
N
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation