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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
BRPF3
Full Name:
Bromodomain and PHD finger-containing protein 3
Alias:
Bromodomain and PHD finger containing, 3; KIAA1286
Type:
Zinc finger protein
Mass (Da):
135745
Number AA:
1205
UniProt ID:
Q9ULD4
International Prot ID:
IPI00008054
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0070776
GO:0005829
GO:0005576
Uniprot
OncoNet
Molecular Function:
GO:0005515
GO:0008270
PhosphoSite+
KinaseNET
Biological Process:
GO:0043966
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S8
M
R
K
P
R
R
K
S
R
Q
N
A
E
G
R
Site 2
S17
Q
N
A
E
G
R
R
S
P
S
P
Y
S
L
K
Site 3
S19
A
E
G
R
R
S
P
S
P
Y
S
L
K
C
S
Site 4
Y21
G
R
R
S
P
S
P
Y
S
L
K
C
S
P
T
Site 5
S22
R
R
S
P
S
P
Y
S
L
K
C
S
P
T
R
Site 6
S26
S
P
Y
S
L
K
C
S
P
T
R
E
T
L
T
Site 7
T31
K
C
S
P
T
R
E
T
L
T
Y
A
Q
A
Q
Site 8
Y34
P
T
R
E
T
L
T
Y
A
Q
A
Q
R
I
V
Site 9
S53
D
G
R
L
H
R
I
S
I
Y
D
P
L
K
I
Site 10
T67
I
I
T
E
D
E
L
T
A
Q
D
I
T
E
C
Site 11
T72
E
L
T
A
Q
D
I
T
E
C
N
S
N
K
E
Site 12
S90
Q
P
Q
F
P
G
K
S
K
K
P
S
S
K
G
Site 13
S94
P
G
K
S
K
K
P
S
S
K
G
K
K
K
E
Site 14
S95
G
K
S
K
K
P
S
S
K
G
K
K
K
E
S
Site 15
S102
S
K
G
K
K
K
E
S
C
S
K
H
A
S
G
Site 16
S104
G
K
K
K
E
S
C
S
K
H
A
S
G
T
S
Site 17
S108
E
S
C
S
K
H
A
S
G
T
S
F
H
L
P
Site 18
S111
S
K
H
A
S
G
T
S
F
H
L
P
Q
P
S
Site 19
S118
S
F
H
L
P
Q
P
S
F
R
M
V
D
S
G
Site 20
Y137
A
P
P
L
P
A
A
Y
Y
R
Y
I
E
K
P
Site 21
Y138
P
P
L
P
A
A
Y
Y
R
Y
I
E
K
P
P
Site 22
Y154
D
L
D
A
E
V
E
Y
D
M
D
E
E
D
L
Site 23
S177
K
R
R
V
D
G
H
S
L
V
S
A
D
T
F
Site 24
S195
V
D
R
L
E
K
E
S
Y
L
E
S
R
S
S
Site 25
Y196
D
R
L
E
K
E
S
Y
L
E
S
R
S
S
G
Site 26
S199
E
K
E
S
Y
L
E
S
R
S
S
G
A
Q
Q
Site 27
S201
E
S
Y
L
E
S
R
S
S
G
A
Q
Q
S
L
Site 28
S202
S
Y
L
E
S
R
S
S
G
A
Q
Q
S
L
I
Site 29
S207
R
S
S
G
A
Q
Q
S
L
I
D
E
D
A
F
Site 30
Y248
Q
E
C
Y
G
V
P
Y
I
P
E
G
Q
W
L
Site 31
S262
L
C
R
C
C
L
Q
S
P
S
R
P
V
D
C
Site 32
Y326
A
R
W
K
L
T
C
Y
I
C
K
Q
K
G
L
Site 33
T368
K
I
E
P
M
R
E
T
S
L
N
G
T
I
F
Site 34
S369
I
E
P
M
R
E
T
S
L
N
G
T
I
F
T
Site 35
T380
T
I
F
T
V
R
K
T
A
Y
C
E
A
H
S
Site 36
S387
T
A
Y
C
E
A
H
S
P
P
G
A
A
T
A
Site 37
T393
H
S
P
P
G
A
A
T
A
R
R
K
G
D
S
Site 38
S400
T
A
R
R
K
G
D
S
P
R
S
I
S
E
T
Site 39
S403
R
K
G
D
S
P
R
S
I
S
E
T
G
D
E
Site 40
S405
G
D
S
P
R
S
I
S
E
T
G
D
E
E
G
Site 41
T407
S
P
R
S
I
S
E
T
G
D
E
E
G
L
K
Site 42
S440
A
Q
G
G
V
S
G
S
L
K
G
V
P
K
K
Site 43
S448
L
K
G
V
P
K
K
S
K
M
S
L
K
Q
K
Site 44
T467
P
E
E
A
G
Q
D
T
P
S
T
L
P
M
L
Site 45
S469
E
A
G
Q
D
T
P
S
T
L
P
M
L
A
V
Site 46
Y482
A
V
P
Q
I
P
S
Y
R
L
N
K
I
C
S
Site 47
S489
Y
R
L
N
K
I
C
S
G
L
S
F
Q
R
K
Site 48
S492
N
K
I
C
S
G
L
S
F
Q
R
K
N
Q
F
Site 49
S525
P
L
I
R
R
L
H
S
H
L
Q
S
Q
R
N
Site 50
S529
R
L
H
S
H
L
Q
S
Q
R
N
A
E
Q
R
Site 51
T542
Q
R
E
Q
D
E
K
T
S
A
V
K
E
E
L
Site 52
Y551
A
V
K
E
E
L
K
Y
W
Q
K
L
R
H
D
Site 53
S621
F
A
E
P
V
N
L
S
E
V
P
D
Y
L
E
Site 54
Y626
N
L
S
E
V
P
D
Y
L
E
F
I
S
K
P
Site 55
S637
I
S
K
P
M
D
F
S
T
M
R
R
K
L
E
Site 56
T638
S
K
P
M
D
F
S
T
M
R
R
K
L
E
S
Site 57
S645
T
M
R
R
K
L
E
S
H
L
Y
R
T
L
E
Site 58
Y648
R
K
L
E
S
H
L
Y
R
T
L
E
E
F
E
Site 59
Y702
R
Q
A
E
N
I
G
Y
D
P
E
R
G
T
H
Site 60
T708
G
Y
D
P
E
R
G
T
H
L
P
E
S
P
K
Site 61
S713
R
G
T
H
L
P
E
S
P
K
L
E
D
F
Y
Site 62
Y720
S
P
K
L
E
D
F
Y
R
F
S
W
E
D
V
Site 63
S740
P
E
N
R
A
H
L
S
P
E
V
Q
L
K
E
Site 64
S756
L
E
K
L
D
L
V
S
A
M
R
S
S
G
A
Site 65
S760
D
L
V
S
A
M
R
S
S
G
A
R
T
R
R
Site 66
S761
L
V
S
A
M
R
S
S
G
A
R
T
R
R
V
Site 67
T765
M
R
S
S
G
A
R
T
R
R
V
R
L
L
R
Site 68
S792
P
P
P
P
Q
P
P
S
L
N
K
T
V
S
N
Site 69
T796
Q
P
P
S
L
N
K
T
V
S
N
G
E
L
P
Site 70
S798
P
S
L
N
K
T
V
S
N
G
E
L
P
A
G
Site 71
S830
D
D
G
D
R
D
D
S
K
L
P
P
P
P
T
Site 72
T837
S
K
L
P
P
P
P
T
L
E
P
T
G
P
A
Site 73
S846
E
P
T
G
P
A
P
S
L
S
E
Q
E
S
P
Site 74
S848
T
G
P
A
P
S
L
S
E
Q
E
S
P
P
E
Site 75
S852
P
S
L
S
E
Q
E
S
P
P
E
P
P
T
L
Site 76
T858
E
S
P
P
E
P
P
T
L
K
P
I
N
D
S
Site 77
S865
T
L
K
P
I
N
D
S
K
P
P
S
R
F
L
Site 78
S869
I
N
D
S
K
P
P
S
R
F
L
K
P
R
K
Site 79
S886
E
D
E
L
L
E
K
S
P
L
Q
L
G
N
E
Site 80
S900
E
P
L
Q
R
L
L
S
D
N
G
I
N
R
L
Site 81
S908
D
N
G
I
N
R
L
S
L
M
A
P
D
T
P
Site 82
T918
A
P
D
T
P
A
G
T
P
L
S
G
V
G
R
Site 83
S921
T
P
A
G
T
P
L
S
G
V
G
R
R
T
S
Site 84
T927
L
S
G
V
G
R
R
T
S
V
L
F
K
K
A
Site 85
S928
S
G
V
G
R
R
T
S
V
L
F
K
K
A
K
Site 86
S943
N
G
V
K
L
Q
R
S
P
D
R
V
L
E
N
Site 87
S959
E
D
H
G
V
A
G
S
P
A
S
P
A
S
I
Site 88
S962
G
V
A
G
S
P
A
S
P
A
S
I
E
E
E
Site 89
S965
G
S
P
A
S
P
A
S
I
E
E
E
R
H
S
Site 90
S972
S
I
E
E
E
R
H
S
R
K
R
P
R
S
R
Site 91
S978
H
S
R
K
R
P
R
S
R
S
C
S
E
S
E
Site 92
S980
R
K
R
P
R
S
R
S
C
S
E
S
E
G
E
Site 93
S982
R
P
R
S
R
S
C
S
E
S
E
G
E
R
S
Site 94
S984
R
S
R
S
C
S
E
S
E
G
E
R
S
P
Q
Site 95
S989
S
E
S
E
G
E
R
S
P
Q
Q
E
E
E
T
Site 96
T999
Q
E
E
E
T
G
M
T
N
G
F
G
K
H
T
Site 97
T1006
T
N
G
F
G
K
H
T
E
S
G
S
D
S
E
Site 98
S1008
G
F
G
K
H
T
E
S
G
S
D
S
E
C
S
Site 99
S1010
G
K
H
T
E
S
G
S
D
S
E
C
S
L
G
Site 100
S1012
H
T
E
S
G
S
D
S
E
C
S
L
G
L
S
Site 101
S1015
S
G
S
D
S
E
C
S
L
G
L
S
G
G
L
Site 102
T1031
F
E
A
C
S
G
L
T
P
P
K
R
S
R
G
Site 103
S1043
S
R
G
K
P
A
L
S
R
V
P
F
L
E
G
Site 104
S1055
L
E
G
V
N
G
D
S
D
Y
N
G
S
G
R
Site 105
Y1057
G
V
N
G
D
S
D
Y
N
G
S
G
R
S
L
Site 106
S1060
G
D
S
D
Y
N
G
S
G
R
S
L
L
L
P
Site 107
S1089
A
K
C
R
G
Y
P
S
Y
P
A
L
I
I
D
Site 108
Y1090
K
C
R
G
Y
P
S
Y
P
A
L
I
I
D
P
Site 109
T1173
K
M
L
E
G
R
K
T
S
I
R
K
S
V
Q
Site 110
S1174
M
L
E
G
R
K
T
S
I
R
K
S
V
Q
V
Site 111
S1178
R
K
T
S
I
R
K
S
V
Q
V
A
Y
D
R
Site 112
Y1183
R
K
S
V
Q
V
A
Y
D
R
A
M
I
H
L
Site 113
S1191
D
R
A
M
I
H
L
S
R
V
R
G
P
H
S
Site 114
S1198
S
R
V
R
G
P
H
S
F
V
T
S
S
Y
L
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation