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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
OGDHL
Full Name:
2-oxoglutarate dehydrogenase E1 component-like, mitochondrial
Alias:
Alpha-ketoglutarate dehydrogenase-like; EC 1.2.4.-; Oxoglutarate dehydrogenase-like
Type:
Enzyme - Dehydrogenase; Mitochondria, mitochondrial matrix
Mass (Da):
114481
Number AA:
1010
UniProt ID:
Q9ULD0
International Prot ID:
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005759
Uniprot
OncoNet
Molecular Function:
GO:0004591
GO:0030976
PhosphoSite+
KinaseNET
Biological Process:
GO:0006096
GO:0055114
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S31
V
P
V
F
G
W
R
S
R
S
S
G
P
P
A
Site 2
S33
V
F
G
W
R
S
R
S
S
G
P
P
A
T
F
Site 3
S34
F
G
W
R
S
R
S
S
G
P
P
A
T
F
P
Site 4
T39
R
S
S
G
P
P
A
T
F
P
S
S
K
G
G
Site 5
S42
G
P
P
A
T
F
P
S
S
K
G
G
G
G
S
Site 6
S43
P
P
A
T
F
P
S
S
K
G
G
G
G
S
S
Site 7
S49
S
S
K
G
G
G
G
S
S
Y
M
E
E
M
Y
Site 8
S50
S
K
G
G
G
G
S
S
Y
M
E
E
M
Y
F
Site 9
Y51
K
G
G
G
G
S
S
Y
M
E
E
M
Y
F
A
Site 10
Y56
S
S
Y
M
E
E
M
Y
F
A
W
L
E
N
P
Site 11
S65
A
W
L
E
N
P
Q
S
V
H
K
S
W
D
S
Site 12
S69
N
P
Q
S
V
H
K
S
W
D
S
F
F
R
E
Site 13
S72
S
V
H
K
S
W
D
S
F
F
R
E
A
S
E
Site 14
S78
D
S
F
F
R
E
A
S
E
E
A
F
S
G
S
Site 15
S83
E
A
S
E
E
A
F
S
G
S
A
Q
P
R
P
Site 16
S85
S
E
E
A
F
S
G
S
A
Q
P
R
P
P
S
Site 17
S92
S
A
Q
P
R
P
P
S
V
V
H
E
S
R
S
Site 18
S97
P
P
S
V
V
H
E
S
R
S
A
V
S
S
R
Site 19
S99
S
V
V
H
E
S
R
S
A
V
S
S
R
T
K
Site 20
S102
H
E
S
R
S
A
V
S
S
R
T
K
T
S
K
Site 21
S103
E
S
R
S
A
V
S
S
R
T
K
T
S
K
L
Site 22
T107
A
V
S
S
R
T
K
T
S
K
L
V
E
D
H
Site 23
S119
E
D
H
L
A
V
Q
S
L
I
R
A
Y
Q
I
Site 24
Y124
V
Q
S
L
I
R
A
Y
Q
I
R
G
H
H
V
Site 25
Y162
T
I
D
K
L
A
F
Y
D
L
Q
E
A
D
L
Site 26
T178
K
E
F
Q
L
P
T
T
T
F
I
G
G
S
E
Site 27
T179
E
F
Q
L
P
T
T
T
F
I
G
G
S
E
N
Site 28
S189
G
G
S
E
N
T
L
S
L
R
E
I
I
R
R
Site 29
Y201
I
R
R
L
E
N
T
Y
C
Q
H
I
G
L
E
Site 30
T227
W
I
R
Q
K
F
E
T
P
G
V
M
Q
F
S
Site 31
S235
P
G
V
M
Q
F
S
S
E
E
K
R
T
L
L
Site 32
T240
F
S
S
E
E
K
R
T
L
L
A
R
L
V
R
Site 33
S260
D
F
L
A
R
K
W
S
S
E
K
R
F
G
L
Site 34
S261
F
L
A
R
K
W
S
S
E
K
R
F
G
L
E
Site 35
S284
L
K
T
I
I
D
K
S
S
E
M
G
I
E
N
Site 36
S285
K
T
I
I
D
K
S
S
E
M
G
I
E
N
V
Site 37
Y336
E
G
S
G
D
V
K
Y
H
L
G
M
Y
H
E
Site 38
Y341
V
K
Y
H
L
G
M
Y
H
E
R
I
N
R
V
Site 39
T349
H
E
R
I
N
R
V
T
N
R
N
I
T
L
S
Site 40
T354
R
V
T
N
R
N
I
T
L
S
L
V
A
N
P
Site 41
S356
T
N
R
N
I
T
L
S
L
V
A
N
P
S
H
Site 42
T410
G
Q
G
V
V
Y
E
T
F
H
L
S
D
L
P
Site 43
S414
V
Y
E
T
F
H
L
S
D
L
P
S
Y
T
T
Site 44
S418
F
H
L
S
D
L
P
S
Y
T
T
N
G
T
V
Site 45
Y419
H
L
S
D
L
P
S
Y
T
T
N
G
T
V
H
Site 46
T420
L
S
D
L
P
S
Y
T
T
N
G
T
V
H
V
Site 47
T424
P
S
Y
T
T
N
G
T
V
H
V
V
V
N
N
Site 48
S445
D
P
R
M
A
R
S
S
P
Y
P
T
D
V
A
Site 49
Y447
R
M
A
R
S
S
P
Y
P
T
D
V
A
R
V
Site 50
T449
A
R
S
S
P
Y
P
T
D
V
A
R
V
V
N
Site 51
T483
V
A
A
E
W
R
N
T
F
N
K
D
V
V
V
Site 52
Y495
V
V
V
D
L
V
C
Y
R
R
R
G
H
N
E
Site 53
T509
E
M
D
E
P
M
F
T
Q
P
L
M
Y
K
Q
Site 54
Y514
M
F
T
Q
P
L
M
Y
K
Q
I
H
R
Q
V
Site 55
T538
L
I
A
E
G
T
V
T
L
Q
E
F
E
E
E
Site 56
Y549
F
E
E
E
I
A
K
Y
D
R
I
C
E
E
A
Site 57
Y557
D
R
I
C
E
E
A
Y
G
R
S
K
D
K
K
Site 58
S588
N
V
D
G
E
P
K
S
M
T
C
P
A
T
G
Site 59
T590
D
G
E
P
K
S
M
T
C
P
A
T
G
I
P
Site 60
T594
K
S
M
T
C
P
A
T
G
I
P
E
D
M
L
Site 61
S610
H
I
G
S
V
A
S
S
V
P
L
E
D
F
K
Site 62
T633
L
R
G
R
A
D
M
T
K
N
R
T
V
D
W
Site 63
T637
A
D
M
T
K
N
R
T
V
D
W
A
L
A
E
Site 64
S661
E
G
I
H
V
R
L
S
G
Q
D
V
E
R
G
Site 65
T669
G
Q
D
V
E
R
G
T
F
S
H
R
H
H
V
Site 66
T686
D
Q
E
V
D
R
R
T
C
V
P
M
N
H
L
Site 67
Y700
L
W
P
D
Q
A
P
Y
T
V
C
N
S
S
L
Site 68
T701
W
P
D
Q
A
P
Y
T
V
C
N
S
S
L
S
Site 69
S778
E
G
M
G
P
E
H
S
S
A
R
P
E
R
F
Site 70
S779
G
M
G
P
E
H
S
S
A
R
P
E
R
F
L
Site 71
S789
P
E
R
F
L
Q
M
S
N
D
D
S
D
A
Y
Site 72
S793
L
Q
M
S
N
D
D
S
D
A
Y
P
A
F
T
Site 73
Y796
S
N
D
D
S
D
A
Y
P
A
F
T
K
D
F
Site 74
Y824
N
C
S
T
P
A
N
Y
F
H
V
L
R
R
Q
Site 75
T844
R
K
P
L
I
I
F
T
P
K
S
L
L
R
H
Site 76
S856
L
R
H
P
E
A
K
S
S
F
D
Q
M
V
S
Site 77
S857
R
H
P
E
A
K
S
S
F
D
Q
M
V
S
G
Site 78
S863
S
S
F
D
Q
M
V
S
G
T
S
F
Q
R
V
Site 79
S866
D
Q
M
V
S
G
T
S
F
Q
R
V
I
P
E
Site 80
Y896
F
C
T
G
K
V
Y
Y
D
L
V
K
E
R
S
Site 81
S904
D
L
V
K
E
R
S
S
Q
D
L
E
E
K
V
Site 82
Y934
I
K
Q
E
A
E
K
Y
P
G
A
E
L
A
W
Site 83
Y951
E
E
H
K
N
M
G
Y
Y
D
Y
I
S
P
R
Site 84
Y952
E
H
K
N
M
G
Y
Y
D
Y
I
S
P
R
F
Site 85
Y954
K
N
M
G
Y
Y
D
Y
I
S
P
R
F
M
T
Site 86
T961
Y
I
S
P
R
F
M
T
I
L
R
R
A
R
P
Site 87
Y971
R
R
A
R
P
I
W
Y
V
G
R
D
P
A
A
Site 88
T982
D
P
A
A
A
P
A
T
G
N
R
N
T
H
L
Site 89
T987
P
A
T
G
N
R
N
T
H
L
V
S
L
K
K
Site 90
S991
N
R
N
T
H
L
V
S
L
K
K
F
L
D
T
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation