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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
TrpC5
Full Name:
Short transient receptor potential channel 5
Alias:
Htrp5; Htrp-5; Transient receptor potential cation channel, subfamily C, member 5; TRP5; TRPC5
Type:
Channel protein
Mass (Da):
111412
Number AA:
973
UniProt ID:
Q9UL62
International Prot ID:
IPI00007836
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005887
Uniprot
OncoNet
Molecular Function:
GO:0005509
GO:0005515
GO:0015279
PhosphoSite+
KinaseNET
Biological Process:
GO:0006816
GO:0007399
GO:0055085
Phosida
TranscriptoNet
STRING
Kinexus Products
Short transient receptor potential channel 5 pan-specific antibody AB-NN350-1#http://www.kinexusproducts.ca/ProductInfo_Antibody.aspx?Product_Number=AB-NN350-1
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S12
Y
Y
K
K
V
N
Y
S
P
Y
R
D
R
I
P
Site 2
Y14
K
K
V
N
Y
S
P
Y
R
D
R
I
P
L
Q
Site 3
T27
L
Q
I
V
R
A
E
T
E
L
S
A
E
E
K
Site 4
S30
V
R
A
E
T
E
L
S
A
E
E
K
A
F
L
Site 5
Y45
N
A
V
E
K
G
D
Y
A
T
V
K
Q
A
L
Site 6
T47
V
E
K
G
D
Y
A
T
V
K
Q
A
L
Q
E
Site 7
Y58
A
L
Q
E
A
E
I
Y
Y
N
V
N
I
N
C
Site 8
Y59
L
Q
E
A
E
I
Y
Y
N
V
N
I
N
C
M
Site 9
S117
G
A
V
E
L
L
L
S
Y
R
R
P
S
G
E
Site 10
Y118
A
V
E
L
L
L
S
Y
R
R
P
S
G
E
K
Site 11
S122
L
L
S
Y
R
R
P
S
G
E
K
Q
V
P
T
Site 12
T134
V
P
T
L
M
M
D
T
Q
F
S
E
F
T
P
Site 13
T140
D
T
Q
F
S
E
F
T
P
D
I
T
P
I
M
Site 14
T167
L
L
V
Q
K
R
V
T
I
P
R
P
H
Q
I
Site 15
S183
C
N
C
V
E
C
V
S
S
S
E
V
D
S
L
Site 16
S184
N
C
V
E
C
V
S
S
S
E
V
D
S
L
R
Site 17
S185
C
V
E
C
V
S
S
S
E
V
D
S
L
R
H
Site 18
S189
V
S
S
S
E
V
D
S
L
R
H
S
R
S
R
Site 19
S193
E
V
D
S
L
R
H
S
R
S
R
L
N
I
Y
Site 20
S195
D
S
L
R
H
S
R
S
R
L
N
I
Y
K
A
Site 21
Y200
S
R
S
R
L
N
I
Y
K
A
L
A
S
P
S
Site 22
T219
S
S
E
D
P
I
L
T
A
F
R
L
G
W
E
Site 23
S231
G
W
E
L
K
E
L
S
K
V
E
N
E
F
K
Site 24
Y241
E
N
E
F
K
A
E
Y
E
E
L
S
Q
Q
C
Site 25
S245
K
A
E
Y
E
E
L
S
Q
Q
C
K
L
F
A
Site 26
S261
D
L
L
D
Q
A
R
S
S
R
E
L
E
I
I
Site 27
S262
L
L
D
Q
A
R
S
S
R
E
L
E
I
I
L
Site 28
S276
L
N
H
R
D
D
H
S
E
E
L
D
P
Q
K
Site 29
Y284
E
E
L
D
P
Q
K
Y
H
D
L
A
K
L
K
Site 30
Y296
K
L
K
V
A
I
K
Y
H
Q
K
E
F
V
A
Site 31
Y316
Q
L
L
A
T
L
W
Y
D
G
F
P
G
W
R
Site 32
Y460
K
I
V
A
Y
V
K
Y
N
G
S
R
P
R
E
Site 33
S463
A
Y
V
K
Y
N
G
S
R
P
R
E
E
W
E
Site 34
T498
L
R
L
I
S
L
F
T
A
N
S
H
L
G
P
Site 35
Y539
A
N
G
L
N
Q
L
Y
F
Y
Y
E
T
R
A
Site 36
Y541
G
L
N
Q
L
Y
F
Y
Y
E
T
R
A
I
D
Site 37
S566
E
K
Q
N
N
A
F
S
T
L
F
E
T
L
Q
Site 38
T567
K
Q
N
N
A
F
S
T
L
F
E
T
L
Q
S
Site 39
Y586
V
F
G
L
L
N
L
Y
V
T
N
V
K
A
R
Site 40
Y628
I
A
M
M
N
N
S
Y
Q
L
I
A
D
H
A
Site 41
S649
A
R
T
K
L
W
M
S
Y
F
D
E
G
G
T
Site 42
Y650
R
T
K
L
W
M
S
Y
F
D
E
G
G
T
L
Site 43
T656
S
Y
F
D
E
G
G
T
L
P
P
P
F
N
I
Site 44
S666
P
P
F
N
I
I
P
S
P
K
S
F
L
Y
L
Site 45
S669
N
I
I
P
S
P
K
S
F
L
Y
L
G
N
W
Site 46
Y672
P
S
P
K
S
F
L
Y
L
G
N
W
F
N
N
Site 47
T680
L
G
N
W
F
N
N
T
F
C
P
K
R
D
P
Site 48
S698
R
R
R
R
N
L
R
S
F
T
E
R
N
A
D
Site 49
T700
R
R
N
L
R
S
F
T
E
R
N
A
D
S
L
Site 50
Y713
S
L
I
Q
N
Q
H
Y
Q
E
V
I
R
N
L
Site 51
S732
V
A
A
M
I
R
N
S
K
T
H
E
G
L
T
Site 52
T734
A
M
I
R
N
S
K
T
H
E
G
L
T
E
E
Site 53
S751
K
E
L
K
Q
D
I
S
S
F
R
Y
E
V
L
Site 54
S752
E
L
K
Q
D
I
S
S
F
R
Y
E
V
L
D
Site 55
Y755
Q
D
I
S
S
F
R
Y
E
V
L
D
L
L
G
Site 56
S769
G
N
R
K
H
P
R
S
F
S
T
S
S
T
E
Site 57
S771
R
K
H
P
R
S
F
S
T
S
S
T
E
L
S
Site 58
S773
H
P
R
S
F
S
T
S
S
T
E
L
S
Q
R
Site 59
S774
P
R
S
F
S
T
S
S
T
E
L
S
Q
R
D
Site 60
T775
R
S
F
S
T
S
S
T
E
L
S
Q
R
D
D
Site 61
S778
S
T
S
S
T
E
L
S
Q
R
D
D
N
N
D
Site 62
S794
S
G
G
A
R
A
K
S
K
S
V
S
F
N
L
Site 63
S796
G
A
R
A
K
S
K
S
V
S
F
N
L
G
C
Site 64
S798
R
A
K
S
K
S
V
S
F
N
L
G
C
K
K
Site 65
T807
N
L
G
C
K
K
K
T
C
H
G
P
P
L
I
Site 66
T816
H
G
P
P
L
I
R
T
M
P
R
S
S
G
A
Site 67
S820
L
I
R
T
M
P
R
S
S
G
A
Q
G
K
S
Site 68
S821
I
R
T
M
P
R
S
S
G
A
Q
G
K
S
K
Site 69
S827
S
S
G
A
Q
G
K
S
K
A
E
S
S
S
K
Site 70
S831
Q
G
K
S
K
A
E
S
S
S
K
R
S
F
M
Site 71
S832
G
K
S
K
A
E
S
S
S
K
R
S
F
M
G
Site 72
S833
K
S
K
A
E
S
S
S
K
R
S
F
M
G
P
Site 73
S836
A
E
S
S
S
K
R
S
F
M
G
P
S
L
K
Site 74
S841
K
R
S
F
M
G
P
S
L
K
K
L
G
L
L
Site 75
S850
K
K
L
G
L
L
F
S
K
F
N
G
H
M
S
Site 76
S857
S
K
F
N
G
H
M
S
E
P
S
S
E
P
M
Site 77
S861
G
H
M
S
E
P
S
S
E
P
M
Y
T
I
S
Site 78
Y865
E
P
S
S
E
P
M
Y
T
I
S
D
G
I
V
Site 79
T866
P
S
S
E
P
M
Y
T
I
S
D
G
I
V
Q
Site 80
S868
S
E
P
M
Y
T
I
S
D
G
I
V
Q
Q
H
Site 81
Y883
C
M
W
Q
D
I
R
Y
S
Q
M
E
K
G
K
Site 82
S895
K
G
K
A
E
A
C
S
Q
S
E
I
N
L
S
Site 83
S897
K
A
E
A
C
S
Q
S
E
I
N
L
S
E
V
Site 84
S902
S
Q
S
E
I
N
L
S
E
V
E
L
G
E
V
Site 85
S930
S
S
S
L
H
C
A
S
S
I
C
S
S
N
S
Site 86
S931
S
S
L
H
C
A
S
S
I
C
S
S
N
S
K
Site 87
S934
H
C
A
S
S
I
C
S
S
N
S
K
L
L
D
Site 88
S935
C
A
S
S
I
C
S
S
N
S
K
L
L
D
S
Site 89
S937
S
S
I
C
S
S
N
S
K
L
L
D
S
S
E
Site 90
S942
S
N
S
K
L
L
D
S
S
E
D
V
F
E
T
Site 91
S943
N
S
K
L
L
D
S
S
E
D
V
F
E
T
W
Site 92
T970
D
G
Q
E
E
Q
V
T
T
R
L
_
_
_
_
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation