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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated November 2019
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Protein Info
Short Name:
PCOLCE2
Full Name:
Procollagen C-endopeptidase enhancer 2
Alias:
Pcoc2; Pcolce2; Pcpe2; Pcpe-2; Procollagen c-endopeptidase enhancer 2; Procollagen cooh-terminal proteinase enhancer 2; Procollagen c-proteinase enhancer 2; Procollagen c-terminal proteinase enhancer protein 2
Type:
Mass (Da):
45717
Number AA:
415
UniProt ID:
Q9UKZ9
International Prot ID:
IPI00002543
Sequence:
Retrieve full protein sequence
GO Terms
External Links
Internal Links
Cellular Component:
GO:0005576
Uniprot
OncoNet
Molecular Function:
GO:0008201
GO:0005515
PhosphoSite+
KinaseNET
Biological Process:
Phosida
TranscriptoNet
STRING
Kinexus Products
Info Box
A variety of parameters were considered in the selection of putative P-sites. Confirmed P-Sites have lower Hydrophobicity Scores. The P-site Similarity Score is lower the more that it resembles typical confirmed corresponding P-Ser, P-Thr or P-Tyr sites. The Maximum KInase Score provides the calculated score for highest match of 500 human protein kinases for the amino acid sequence surrounding the target P-site as determined with Kinase Substrate Predictor V2. The Sum KInase Score provides the additive sum of the positive individual Kinase Substrate Predictor V2 scores from 500 human protein kinases. The Conservation Score is the average of the percent similarity of the human P-site with the equivalent P-site in 20 other diverse species. Click the coloured buttons below to retrieve this and other information in the Info Box, or click the orange buttons for relevant links.
Phosphosites
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Expt. conf.
Effect
Kinase
PPase
Kinexus Products
Ref.
Evol.
Kinase Pred.
P-site Match
Site 1
S21
L
A
A
A
T
Q
L
S
R
Q
Q
S
P
E
R
Site 2
S25
T
Q
L
S
R
Q
Q
S
P
E
R
P
V
F
T
Site 3
S46
G
E
S
G
F
I
G
S
E
G
F
P
G
V
Y
Site 4
Y53
S
E
G
F
P
G
V
Y
P
P
N
S
K
C
T
Site 5
T64
S
K
C
T
W
K
I
T
V
P
E
G
K
V
V
Site 6
S82
F
R
F
I
D
L
E
S
D
N
L
C
R
Y
D
Site 7
Y88
E
S
D
N
L
C
R
Y
D
F
V
D
V
Y
N
Site 8
Y94
R
Y
D
F
V
D
V
Y
N
G
H
A
N
G
Q
Site 9
T132
Q
M
I
S
D
A
N
T
A
G
N
G
F
M
A
Site 10
Y153
P
N
E
R
G
D
Q
Y
C
G
G
L
L
D
R
Site 11
S162
G
G
L
L
D
R
P
S
G
S
F
K
T
P
N
Site 12
S164
L
L
D
R
P
S
G
S
F
K
T
P
N
W
P
Site 13
T167
R
P
S
G
S
F
K
T
P
N
W
P
D
R
D
Site 14
Y175
P
N
W
P
D
R
D
Y
P
A
G
V
T
C
V
Site 15
Y207
F
D
V
E
R
D
N
Y
C
R
Y
D
Y
V
A
Site 16
Y210
E
R
D
N
Y
C
R
Y
D
Y
V
A
V
F
N
Site 17
Y212
D
N
Y
C
R
Y
D
Y
V
A
V
F
N
G
G
Site 18
Y230
D
A
R
R
I
G
K
Y
C
G
D
S
P
P
A
Site 19
S234
I
G
K
Y
C
G
D
S
P
P
A
P
I
V
S
Site 20
S241
S
P
P
A
P
I
V
S
E
R
N
E
L
L
I
Site 21
Y265
A
D
G
F
I
G
H
Y
I
F
R
P
K
K
L
Site 22
T276
P
K
K
L
P
T
T
T
E
Q
P
V
T
T
T
Site 23
T281
T
T
T
E
Q
P
V
T
T
T
F
P
V
T
T
Site 24
T283
T
E
Q
P
V
T
T
T
F
P
V
T
T
G
L
Site 25
T304
C
Q
Q
K
C
R
R
T
G
T
L
E
G
N
Y
Site 26
T306
Q
K
C
R
R
T
G
T
L
E
G
N
Y
C
S
Site 27
Y311
T
G
T
L
E
G
N
Y
C
S
S
D
F
V
L
Site 28
S331
T
T
I
T
R
D
G
S
L
H
A
T
V
S
I
Site 29
S337
G
S
L
H
A
T
V
S
I
I
N
I
Y
K
E
Site 30
S357
Q
Q
A
G
K
N
M
S
A
R
L
T
V
V
C
Site 31
T361
K
N
M
S
A
R
L
T
V
V
C
K
Q
C
P
Site 32
T401
S
F
I
M
M
F
K
T
K
N
Q
K
L
L
D
Legend
Confirmed in mammals
Confirmed in related proteins or other species
Predicted by Kinexus P-Site Prediction algorithm
No data/link available
Link available
Products available
2019 Kinexus Bioinformatics Corporation